Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ATRIA_UP |
| Enrichment Score (ES) | -0.51243585 |
| Normalized Enrichment Score (NES) | -1.9491371 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.014650031 |
| FWER p-Value | 0.414 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HYOU1 | HYOU1 Entrez, Source | hypoxia up-regulated 1 | 68 | 0.255 | 0.0200 | No |
| 2 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 381 | 0.138 | 0.0100 | No |
| 3 | FGFR2 | FGFR2 Entrez, Source | ffer syndrome, Jackson-Weiss syndrome) | 419 | 0.133 | 0.0203 | No |
| 4 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 681 | 0.113 | 0.0117 | No |
| 5 | CALR | CALR Entrez, Source | calreticulin | 768 | 0.108 | 0.0158 | No |
| 6 | POLD4 | POLD4 Entrez, Source | polymerase (DNA-directed), delta 4 | 869 | 0.104 | 0.0185 | No |
| 7 | FGL2 | FGL2 Entrez, Source | fibrinogen-like 2 | 897 | 0.103 | 0.0266 | No |
| 8 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | -0.0106 | No |
| 9 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 1622 | 0.077 | -0.0128 | No |
| 10 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 1957 | 0.069 | -0.0313 | No |
| 11 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 2269 | 0.063 | -0.0486 | No |
| 12 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 2381 | 0.061 | -0.0511 | No |
| 13 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2418 | 0.060 | -0.0479 | No |
| 14 | FBLN2 | FBLN2 Entrez, Source | fibulin 2 | 2463 | 0.059 | -0.0454 | No |
| 15 | CREB3L2 | CREB3L2 Entrez, Source | cAMP responsive element binding protein 3-like 2 | 2599 | 0.057 | -0.0500 | No |
| 16 | FMOD | FMOD Entrez, Source | fibromodulin | 2602 | 0.057 | -0.0445 | No |
| 17 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 2696 | 0.055 | -0.0461 | No |
| 18 | PLA2G5 | PLA2G5 Entrez, Source | phospholipase A2, group V | 2764 | 0.054 | -0.0459 | No |
| 19 | SLN | SLN Entrez, Source | sarcolipin | 2805 | 0.053 | -0.0437 | No |
| 20 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 2896 | 0.052 | -0.0454 | No |
| 21 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 3166 | 0.048 | -0.0611 | No |
| 22 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 3666 | 0.041 | -0.0948 | No |
| 23 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 3777 | 0.040 | -0.0992 | No |
| 24 | VSNL1 | VSNL1 Entrez, Source | visinin-like 1 | 3879 | 0.038 | -0.1031 | No |
| 25 | KDELR2 | KDELR2 Entrez, Source | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 4041 | 0.036 | -0.1118 | No |
| 26 | CACNA1B | CACNA1B Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1B subunit | 4117 | 0.035 | -0.1140 | No |
| 27 | RARRES2 | RARRES2 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 2 | 4262 | 0.033 | -0.1217 | No |
| 28 | DGKZ | DGKZ Entrez, Source | diacylglycerol kinase, zeta 104kDa | 4311 | 0.032 | -0.1221 | No |
| 29 | KCNA5 | KCNA5 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 5 | 4364 | 0.032 | -0.1229 | No |
| 30 | CELSR2 | CELSR2 Entrez, Source | cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) | 4367 | 0.032 | -0.1199 | No |
| 31 | SYNPO | SYNPO Entrez, Source | synaptopodin | 4486 | 0.030 | -0.1259 | No |
| 32 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 4499 | 0.030 | -0.1239 | No |
| 33 | RBP1 | RBP1 Entrez, Source | retinol binding protein 1, cellular | 4518 | 0.030 | -0.1223 | No |
| 34 | SOD3 | SOD3 Entrez, Source | superoxide dismutase 3, extracellular | 4541 | 0.030 | -0.1210 | No |
| 35 | TBX5 | TBX5 Entrez, Source | T-box 5 | 4682 | 0.028 | -0.1289 | No |
| 36 | PTHR1 | PTHR1 Entrez, Source | parathyroid hormone receptor 1 | 4833 | 0.026 | -0.1377 | No |
| 37 | CHRNE | CHRNE Entrez, Source | cholinergic receptor, nicotinic, epsilon | 5036 | 0.023 | -0.1507 | No |
| 38 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 5065 | 0.023 | -0.1505 | No |
| 39 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 5085 | 0.023 | -0.1497 | No |
| 40 | MIPEP | MIPEP Entrez, Source | mitochondrial intermediate peptidase | 5270 | 0.021 | -0.1616 | No |
| 41 | AFAP | AFAP Entrez, Source | - | 5277 | 0.021 | -0.1601 | No |
| 42 | PDE8B | PDE8B Entrez, Source | phosphodiesterase 8B | 5598 | 0.017 | -0.1826 | No |
| 43 | SLIT3 | SLIT3 Entrez, Source | slit homolog 3 (Drosophila) | 5618 | 0.017 | -0.1824 | No |
| 44 | NTRK2 | NTRK2 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 2 | 5630 | 0.017 | -0.1816 | No |
| 45 | C10ORF7 | C10ORF7 Entrez, Source | chromosome 10 open reading frame 7 | 5783 | 0.015 | -0.1916 | No |
| 46 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 5874 | 0.014 | -0.1970 | No |
| 47 | KCNK3 | KCNK3 Entrez, Source | potassium channel, subfamily K, member 3 | 5875 | 0.014 | -0.1956 | No |
| 48 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 5884 | 0.014 | -0.1948 | No |
| 49 | CADPS | CADPS Entrez, Source | Ca2+-dependent secretion activator | 6133 | 0.012 | -0.2125 | No |
| 50 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 6263 | 0.010 | -0.2212 | No |
| 51 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 6360 | 0.009 | -0.2276 | No |
| 52 | PPIB | PPIB Entrez, Source | peptidylprolyl isomerase B (cyclophilin B) | 6516 | 0.007 | -0.2386 | No |
| 53 | SLC39A8 | SLC39A8 Entrez, Source | solute carrier family 39 (zinc transporter), member 8 | 6573 | 0.007 | -0.2422 | No |
| 54 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 6869 | 0.003 | -0.2642 | No |
| 55 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 6986 | 0.002 | -0.2728 | No |
| 56 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7012 | 0.002 | -0.2745 | No |
| 57 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 7053 | 0.001 | -0.2774 | No |
| 58 | TGFB1I1 | TGFB1I1 Entrez, Source | transforming growth factor beta 1 induced transcript 1 | 7121 | 0.001 | -0.2824 | No |
| 59 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 7124 | 0.001 | -0.2825 | No |
| 60 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 7179 | 0.000 | -0.2865 | No |
| 61 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 7242 | -0.001 | -0.2912 | No |
| 62 | FEV | FEV Entrez, Source | FEV (ETS oncogene family) | 7265 | -0.001 | -0.2927 | No |
| 63 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 7275 | -0.001 | -0.2933 | No |
| 64 | GNB5 | GNB5 Entrez, Source | guanine nucleotide binding protein (G protein), beta 5 | 7364 | -0.002 | -0.2998 | No |
| 65 | KCNK1 | KCNK1 Entrez, Source | potassium channel, subfamily K, member 1 | 7451 | -0.003 | -0.3060 | No |
| 66 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 7563 | -0.004 | -0.3139 | No |
| 67 | FEZ1 | FEZ1 Entrez, Source | fasciculation and elongation protein zeta 1 (zygin I) | 7687 | -0.006 | -0.3227 | No |
| 68 | SFRP1 | SFRP1 Entrez, Source | secreted frizzled-related protein 1 | 7830 | -0.007 | -0.3327 | No |
| 69 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 7919 | -0.009 | -0.3385 | No |
| 70 | TMEM106C | TMEM106C Entrez, Source | transmembrane protein 106C | 8042 | -0.010 | -0.3468 | No |
| 71 | PRDX1 | PRDX1 Entrez, Source | peroxiredoxin 1 | 8062 | -0.010 | -0.3472 | No |
| 72 | TMED3 | TMED3 Entrez, Source | transmembrane emp24 protein transport domain containing 3 | 8135 | -0.011 | -0.3516 | No |
| 73 | GRIN2C | GRIN2C Entrez, Source | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 8212 | -0.012 | -0.3562 | No |
| 74 | SLC22A18 | SLC22A18 Entrez, Source | solute carrier family 22 (organic cation transporter), member 18 | 8447 | -0.015 | -0.3724 | No |
| 75 | NRTN | NRTN Entrez, Source | neurturin | 9082 | -0.023 | -0.4181 | No |
| 76 | TOR1A | TOR1A Entrez, Source | torsin family 1, member A (torsin A) | 9104 | -0.023 | -0.4174 | No |
| 77 | INPP1 | INPP1 Entrez, Source | inositol polyphosphate-1-phosphatase | 9155 | -0.024 | -0.4189 | No |
| 78 | PLOD3 | PLOD3 Entrez, Source | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | 9156 | -0.024 | -0.4165 | No |
| 79 | FRMD4B | FRMD4B Entrez, Source | FERM domain containing 4B | 9173 | -0.024 | -0.4154 | No |
| 80 | DHODH | DHODH Entrez, Source | dihydroorotate dehydrogenase | 9238 | -0.025 | -0.4178 | No |
| 81 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 9246 | -0.025 | -0.4158 | No |
| 82 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 9384 | -0.027 | -0.4235 | No |
| 83 | PIP5K2B | PIP5K2B Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type II, beta | 9494 | -0.029 | -0.4289 | No |
| 84 | PDE2A | PDE2A Entrez, Source | phosphodiesterase 2A, cGMP-stimulated | 9739 | -0.033 | -0.4442 | No |
| 85 | PLXNB2 | PLXNB2 Entrez, Source | plexin B2 | 9766 | -0.033 | -0.4429 | No |
| 86 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 9838 | -0.034 | -0.4450 | No |
| 87 | AGTR1 | AGTR1 Entrez, Source | angiotensin II receptor, type 1 | 9880 | -0.035 | -0.4447 | No |
| 88 | PDLIM4 | PDLIM4 Entrez, Source | PDZ and LIM domain 4 | 9887 | -0.035 | -0.4417 | No |
| 89 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 10292 | -0.041 | -0.4682 | No |
| 90 | SMARCD2 | SMARCD2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 10300 | -0.041 | -0.4647 | No |
| 91 | ZFP36L2 | ZFP36L2 Entrez, Source | zinc finger protein 36, C3H type-like 2 | 10449 | -0.044 | -0.4715 | No |
| 92 | USP11 | USP11 Entrez, Source | ubiquitin specific peptidase 11 | 10587 | -0.047 | -0.4773 | No |
| 93 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 10845 | -0.053 | -0.4916 | No |
| 94 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 10906 | -0.054 | -0.4908 | No |
| 95 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 11098 | -0.058 | -0.4996 | No |
| 96 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11206 | -0.060 | -0.5017 | No |
| 97 | TNK2 | TNK2 Entrez, Source | tyrosine kinase, non-receptor, 2 | 11220 | -0.061 | -0.4967 | No |
| 98 | COMP | COMP Entrez, Source | cartilage oligomeric matrix protein | 11234 | -0.061 | -0.4917 | No |
| 99 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11428 | -0.066 | -0.4998 | No |
| 100 | IGFBP6 | IGFBP6 Entrez, Source | insulin-like growth factor binding protein 6 | 11430 | -0.066 | -0.4934 | No |
| 101 | CD81 | CD81 Entrez, Source | CD81 molecule | 11591 | -0.072 | -0.4985 | No |
| 102 | DPYSL3 | DPYSL3 Entrez, Source | dihydropyrimidinase-like 3 | 11772 | -0.078 | -0.5044 | Yes |
| 103 | DAP | DAP Entrez, Source | death-associated protein | 11879 | -0.082 | -0.5043 | Yes |
| 104 | RABAC1 | RABAC1 Entrez, Source | Rab acceptor 1 (prenylated) | 11913 | -0.084 | -0.4986 | Yes |
| 105 | RELN | RELN Entrez, Source | reelin | 12016 | -0.088 | -0.4976 | Yes |
| 106 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12081 | -0.091 | -0.4935 | Yes |
| 107 | CRMP1 | CRMP1 Entrez, Source | collapsin response mediator protein 1 | 12101 | -0.091 | -0.4860 | Yes |
| 108 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 12235 | -0.099 | -0.4863 | Yes |
| 109 | VAMP5 | VAMP5 Entrez, Source | vesicle-associated membrane protein 5 (myobrevin) | 12296 | -0.103 | -0.4807 | Yes |
| 110 | WISP2 | WISP2 Entrez, Source | WNT1 inducible signaling pathway protein 2 | 12345 | -0.107 | -0.4738 | Yes |
| 111 | PLCB1 | PLCB1 Entrez, Source | phospholipase C, beta 1 (phosphoinositide-specific) | 12348 | -0.107 | -0.4634 | Yes |
| 112 | SGCE | SGCE Entrez, Source | sarcoglycan, epsilon | 12384 | -0.110 | -0.4552 | Yes |
| 113 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 12535 | -0.120 | -0.4547 | Yes |
| 114 | MAGED1 | MAGED1 Entrez, Source | melanoma antigen family D, 1 | 12552 | -0.121 | -0.4440 | Yes |
| 115 | VAT1 | VAT1 Entrez, Source | vesicle amine transport protein 1 homolog (T californica) | 12596 | -0.125 | -0.4349 | Yes |
| 116 | DAPK2 | DAPK2 Entrez, Source | death-associated protein kinase 2 | 12720 | -0.137 | -0.4307 | Yes |
| 117 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12745 | -0.140 | -0.4187 | Yes |
| 118 | CTSF | CTSF Entrez, Source | cathepsin F | 12816 | -0.150 | -0.4092 | Yes |
| 119 | CSRP1 | CSRP1 Entrez, Source | cysteine and glycine-rich protein 1 | 12832 | -0.153 | -0.3953 | Yes |
| 120 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 12954 | -0.177 | -0.3871 | Yes |
| 121 | CD47 | CD47 Entrez, Source | CD47 molecule | 12956 | -0.177 | -0.3697 | Yes |
| 122 | GRN | GRN Entrez, Source | granulin | 12971 | -0.181 | -0.3529 | Yes |
| 123 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 13121 | -0.240 | -0.3406 | Yes |
| 124 | BASP1 | BASP1 Entrez, Source | brain abundant, membrane attached signal protein 1 | 13161 | -0.265 | -0.3174 | Yes |
| 125 | RTN4 | RTN4 Entrez, Source | reticulon 4 | 13167 | -0.269 | -0.2913 | Yes |
| 126 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 13175 | -0.275 | -0.2647 | Yes |
| 127 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 13213 | -0.306 | -0.2374 | Yes |
| 128 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13242 | -0.345 | -0.2056 | Yes |
| 129 | IL1RL1 | IL1RL1 Entrez, Source | interleukin 1 receptor-like 1 | 13263 | -0.378 | -0.1699 | Yes |
| 130 | ADM | ADM Entrez, Source | adrenomedullin | 13274 | -0.393 | -0.1319 | Yes |
| 131 | CPE | CPE Entrez, Source | carboxypeptidase E | 13284 | -0.413 | -0.0919 | Yes |
| 132 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.0467 | Yes |
| 133 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13313 | -0.503 | 0.0022 | Yes |
