Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | BRCA1_MES_UP |
| Enrichment Score (ES) | -0.6886015 |
| Normalized Enrichment Score (NES) | -2.0290434 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006366678 |
| FWER p-Value | 0.149 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FGFBP1 | FGFBP1 Entrez, Source | fibroblast growth factor binding protein 1 | 202 | 0.172 | 0.0339 | No |
| 2 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 873 | 0.104 | 0.0131 | No |
| 3 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 1544 | 0.078 | -0.0149 | No |
| 4 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2076 | 0.066 | -0.0359 | No |
| 5 | DDX3X | DDX3X Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked | 4329 | 0.032 | -0.1959 | No |
| 6 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 4387 | 0.031 | -0.1912 | No |
| 7 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 4657 | 0.028 | -0.2035 | No |
| 8 | EIF3S8 | EIF3S8 Entrez, Source | eukaryotic translation initiation factor 3, subunit 8, 110kDa | 4984 | 0.024 | -0.2211 | No |
| 9 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 5084 | 0.023 | -0.2221 | No |
| 10 | ARF1 | ARF1 Entrez, Source | ADP-ribosylation factor 1 | 6593 | 0.007 | -0.3335 | No |
| 11 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 7034 | 0.002 | -0.3661 | No |
| 12 | LXN | LXN Entrez, Source | latexin | 7537 | -0.004 | -0.4026 | No |
| 13 | PSMC1 | PSMC1 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 7772 | -0.007 | -0.4183 | No |
| 14 | DDX24 | DDX24 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 24 | 7882 | -0.008 | -0.4242 | No |
| 15 | DLG1 | DLG1 Entrez, Source | discs, large homolog 1 (Drosophila) | 8290 | -0.013 | -0.4511 | No |
| 16 | PSMC2 | PSMC2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 8416 | -0.014 | -0.4563 | No |
| 17 | ATP6AP1 | ATP6AP1 Entrez, Source | ATPase, H+ transporting, lysosomal accessory protein 1 | 9190 | -0.024 | -0.5075 | No |
| 18 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 9406 | -0.028 | -0.5158 | No |
| 19 | NUMB | NUMB Entrez, Source | numb homolog (Drosophila) | 9714 | -0.032 | -0.5296 | No |
| 20 | APP | APP Entrez, Source | amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease) | 11831 | -0.081 | -0.6657 | Yes |
| 21 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12081 | -0.091 | -0.6585 | Yes |
| 22 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12271 | -0.101 | -0.6440 | Yes |
| 23 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 12514 | -0.118 | -0.6285 | Yes |
| 24 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12599 | -0.125 | -0.5992 | Yes |
| 25 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 12741 | -0.140 | -0.5700 | Yes |
| 26 | ANXA5 | ANXA5 Entrez, Source | annexin A5 | 12886 | -0.162 | -0.5347 | Yes |
| 27 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.4891 | Yes |
| 28 | VIM | VIM Entrez, Source | vimentin | 13040 | -0.204 | -0.4356 | Yes |
| 29 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13112 | -0.236 | -0.3737 | Yes |
| 30 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.2923 | Yes |
| 31 | TAGLN | TAGLN Entrez, Source | transgelin | 13341 | -1.059 | 0.0001 | Yes |
