Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | BRCA_PROGNOSIS_NEG |
| Enrichment Score (ES) | -0.646166 |
| Normalized Enrichment Score (NES) | -2.0097744 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0071265176 |
| FWER p-Value | 0.196 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 439 | 0.131 | -0.0009 | No |
| 2 | NMU | NMU Entrez, Source | neuromedin U | 1515 | 0.079 | -0.0623 | No |
| 3 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 1883 | 0.070 | -0.0726 | No |
| 4 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2629 | 0.056 | -0.1148 | No |
| 5 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 2997 | 0.050 | -0.1301 | No |
| 6 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 3532 | 0.042 | -0.1599 | No |
| 7 | MGAT4A | MGAT4A Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A | 4171 | 0.034 | -0.1994 | No |
| 8 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 4217 | 0.034 | -0.1946 | No |
| 9 | UCHL5 | UCHL5 Entrez, Source | ubiquitin carboxyl-terminal hydrolase L5 | 4937 | 0.025 | -0.2426 | No |
| 10 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 5075 | 0.023 | -0.2473 | No |
| 11 | MCCC1 | MCCC1 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) | 5123 | 0.022 | -0.2453 | No |
| 12 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 5319 | 0.020 | -0.2550 | No |
| 13 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 5619 | 0.017 | -0.2734 | No |
| 14 | PTDSS1 | PTDSS1 Entrez, Source | phosphatidylserine synthase 1 | 6320 | 0.009 | -0.3237 | No |
| 15 | SLC7A1 | SLC7A1 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 6719 | 0.005 | -0.3523 | No |
| 16 | GNAZ | GNAZ Entrez, Source | guanine nucleotide binding protein (G protein), alpha z polypeptide | 7248 | -0.001 | -0.3918 | No |
| 17 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 7426 | -0.003 | -0.4044 | No |
| 18 | ASNS | ASNS Entrez, Source | asparagine synthetase | 7614 | -0.005 | -0.4173 | No |
| 19 | MTDH | MTDH Entrez, Source | metadherin | 7951 | -0.009 | -0.4403 | No |
| 20 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8388 | -0.014 | -0.4697 | No |
| 21 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.4879 | No |
| 22 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9333 | -0.026 | -0.5297 | No |
| 23 | AURKA | AURKA Entrez, Source | aurora kinase A | 9722 | -0.032 | -0.5509 | No |
| 24 | CDC42BPA | CDC42BPA Entrez, Source | CDC42 binding protein kinase alpha (DMPK-like) | 9898 | -0.035 | -0.5555 | No |
| 25 | MRPL13 | MRPL13 Entrez, Source | mitochondrial ribosomal protein L13 | 9905 | -0.035 | -0.5474 | No |
| 26 | DCK | DCK Entrez, Source | deoxycytidine kinase | 10358 | -0.043 | -0.5709 | No |
| 27 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 10619 | -0.047 | -0.5789 | No |
| 28 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 10702 | -0.049 | -0.5729 | No |
| 29 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 11526 | -0.069 | -0.6178 | No |
| 30 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 11904 | -0.084 | -0.6257 | Yes |
| 31 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 11999 | -0.087 | -0.6114 | Yes |
| 32 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 12105 | -0.092 | -0.5969 | Yes |
| 33 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12243 | -0.099 | -0.5829 | Yes |
| 34 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12396 | -0.111 | -0.5672 | Yes |
| 35 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12798 | -0.147 | -0.5612 | Yes |
| 36 | SPBC25 | SPBC25 Entrez, Source | spindle pole body component 25 homolog (S. cerevisiae) | 13182 | -0.282 | -0.5208 | Yes |
| 37 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13242 | -0.345 | -0.4407 | Yes |
| 38 | ADM | ADM Entrez, Source | adrenomedullin | 13274 | -0.393 | -0.3465 | Yes |
| 39 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | -0.2382 | Yes |
| 40 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.1236 | Yes |
| 41 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | 0.0018 | Yes |
