Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | BRENTANI_CELL_CYCLE |
| Enrichment Score (ES) | -0.65061724 |
| Normalized Enrichment Score (NES) | -2.1314876 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.002750866 |
| FWER p-Value | 0.026 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.1225 | No |
| 2 | POLR3D | POLR3D Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa | 3876 | 0.038 | -0.2604 | No |
| 3 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 3927 | 0.037 | -0.2534 | No |
| 4 | CDC2L1 | CDC2L1 Entrez, Source | cell division cycle 2-like 1 (PITSLRE proteins) | 4002 | 0.036 | -0.2485 | No |
| 5 | CCNH | CCNH Entrez, Source | cyclin H | 4088 | 0.035 | -0.2448 | No |
| 6 | CCNF | CCNF Entrez, Source | cyclin F | 4467 | 0.030 | -0.2645 | No |
| 7 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.2866 | No |
| 8 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 4979 | 0.024 | -0.2886 | No |
| 9 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.2848 | No |
| 10 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 5085 | 0.023 | -0.2831 | No |
| 11 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 5568 | 0.017 | -0.3143 | No |
| 12 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.3251 | No |
| 13 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.3231 | No |
| 14 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 5981 | 0.013 | -0.3328 | No |
| 15 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 6706 | 0.005 | -0.3857 | No |
| 16 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6894 | 0.003 | -0.3989 | No |
| 17 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 7275 | -0.001 | -0.4272 | No |
| 18 | SKP1A | SKP1A Entrez, Source | S-phase kinase-associated protein 1A (p19A) | 7360 | -0.002 | -0.4329 | No |
| 19 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 7453 | -0.003 | -0.4389 | No |
| 20 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7469 | -0.003 | -0.4391 | No |
| 21 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 8030 | -0.010 | -0.4784 | No |
| 22 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 8604 | -0.017 | -0.5166 | No |
| 23 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 9024 | -0.022 | -0.5418 | No |
| 24 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5772 | No |
| 25 | MAX | MAX Entrez, Source | MYC associated factor X | 10590 | -0.047 | -0.6372 | Yes |
| 26 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 10614 | -0.047 | -0.6254 | Yes |
| 27 | CDC25B | CDC25B Entrez, Source | cell division cycle 25B | 10619 | -0.047 | -0.6121 | Yes |
| 28 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 10703 | -0.049 | -0.6041 | Yes |
| 29 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 10848 | -0.053 | -0.5998 | Yes |
| 30 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 10979 | -0.055 | -0.5937 | Yes |
| 31 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 11022 | -0.056 | -0.5807 | Yes |
| 32 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 11046 | -0.057 | -0.5661 | Yes |
| 33 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 11337 | -0.063 | -0.5697 | Yes |
| 34 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.5557 | Yes |
| 35 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.5532 | Yes |
| 36 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 11760 | -0.077 | -0.5391 | Yes |
| 37 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 11803 | -0.079 | -0.5195 | Yes |
| 38 | CDC37 | CDC37 Entrez, Source | CDC37 cell division cycle 37 homolog (S. cerevisiae) | 11983 | -0.086 | -0.5082 | Yes |
| 39 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12064 | -0.090 | -0.4884 | Yes |
| 40 | MOS | MOS Entrez, Source | v-mos Moloney murine sarcoma viral oncogene homolog | 12201 | -0.097 | -0.4709 | Yes |
| 41 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12294 | -0.103 | -0.4482 | Yes |
| 42 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12579 | -0.124 | -0.4339 | Yes |
| 43 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12915 | -0.168 | -0.4108 | Yes |
| 44 | FOSL1 | FOSL1 Entrez, Source | FOS-like antigen 1 | 12919 | -0.170 | -0.3622 | Yes |
| 45 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 13022 | -0.195 | -0.3138 | Yes |
| 46 | FRK | FRK Entrez, Source | fyn-related kinase | 13059 | -0.212 | -0.2556 | Yes |
| 47 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | -0.1902 | Yes |
| 48 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13250 | -0.352 | -0.0985 | Yes |
| 49 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13257 | -0.367 | 0.0064 | Yes |
