Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | BRENTANI_DEATH |
| Enrichment Score (ES) | -0.5523414 |
| Normalized Enrichment Score (NES) | -1.7586477 |
| Nominal p-value | 0.011764706 |
| FDR q-value | 0.049343295 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 719 | 0.111 | -0.0173 | No |
| 2 | CASP1 | CASP1 Entrez, Source | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 809 | 0.106 | 0.0114 | No |
| 3 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 1853 | 0.071 | -0.0434 | No |
| 4 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.0232 | No |
| 5 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 4295 | 0.033 | -0.1927 | No |
| 6 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4328 | 0.032 | -0.1844 | No |
| 7 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 4610 | 0.029 | -0.1960 | No |
| 8 | BNIP1 | BNIP1 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 1 | 5150 | 0.022 | -0.2292 | No |
| 9 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 5394 | 0.019 | -0.2410 | No |
| 10 | DAP3 | DAP3 Entrez, Source | death associated protein 3 | 5411 | 0.019 | -0.2359 | No |
| 11 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6778 | 0.004 | -0.3371 | No |
| 12 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 6841 | 0.004 | -0.3405 | No |
| 13 | BCL2L2 | BCL2L2 Entrez, Source | BCL2-like 2 | 7256 | -0.001 | -0.3714 | No |
| 14 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 8465 | -0.015 | -0.4572 | No |
| 15 | LTA | LTA Entrez, Source | lymphotoxin alpha (TNF superfamily, member 1) | 8598 | -0.017 | -0.4615 | No |
| 16 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.4624 | No |
| 17 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8710 | -0.018 | -0.4578 | No |
| 18 | TFPT | TFPT Entrez, Source | TCF3 (E2A) fusion partner (in childhood Leukemia) | 9000 | -0.022 | -0.4723 | No |
| 19 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5081 | No |
| 20 | MYD88 | MYD88 Entrez, Source | myeloid differentiation primary response gene (88) | 10202 | -0.040 | -0.5390 | Yes |
| 21 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10281 | -0.041 | -0.5313 | Yes |
| 22 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 10437 | -0.044 | -0.5283 | Yes |
| 23 | MAX | MAX Entrez, Source | MYC associated factor X | 10590 | -0.047 | -0.5242 | Yes |
| 24 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10657 | -0.048 | -0.5131 | Yes |
| 25 | BAG4 | BAG4 Entrez, Source | BCL2-associated athanogene 4 | 10691 | -0.049 | -0.4993 | Yes |
| 26 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10778 | -0.051 | -0.4887 | Yes |
| 27 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 10848 | -0.053 | -0.4764 | Yes |
| 28 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 10973 | -0.055 | -0.4674 | Yes |
| 29 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 11038 | -0.057 | -0.4533 | Yes |
| 30 | BFAR | BFAR Entrez, Source | bifunctional apoptosis regulator | 11056 | -0.057 | -0.4356 | Yes |
| 31 | BIK | BIK Entrez, Source | BCL2-interacting killer (apoptosis-inducing) | 11095 | -0.058 | -0.4193 | Yes |
| 32 | PLAGL1 | PLAGL1 Entrez, Source | pleiomorphic adenoma gene-like 1 | 11247 | -0.061 | -0.4103 | Yes |
| 33 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 11376 | -0.064 | -0.3985 | Yes |
| 34 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 11387 | -0.065 | -0.3777 | Yes |
| 35 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11428 | -0.066 | -0.3587 | Yes |
| 36 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 11446 | -0.066 | -0.3379 | Yes |
| 37 | DAPK3 | DAPK3 Entrez, Source | death-associated protein kinase 3 | 11659 | -0.074 | -0.3292 | Yes |
| 38 | DAP | DAP Entrez, Source | death-associated protein | 11879 | -0.082 | -0.3183 | Yes |
| 39 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.2986 | Yes |
| 40 | PAWR | PAWR Entrez, Source | PRKC, apoptosis, WT1, regulator | 12073 | -0.090 | -0.2738 | Yes |
| 41 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 12519 | -0.119 | -0.2676 | Yes |
| 42 | NME3 | NME3 Entrez, Source | non-metastatic cells 3, protein expressed in | 12646 | -0.129 | -0.2340 | Yes |
| 43 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 12946 | -0.175 | -0.1984 | Yes |
| 44 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13224 | -0.321 | -0.1126 | Yes |
| 45 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13256 | -0.365 | 0.0065 | Yes |
