Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | BUTANOATE_METABOLISM |
| Enrichment Score (ES) | 0.70703137 |
| Normalized Enrichment Score (NES) | 2.0899656 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0022870044 |
| FWER p-Value | 0.059 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 6 | 0.447 | 0.1940 | Yes |
| 2 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 14 | 0.377 | 0.3576 | Yes |
| 3 | AACS | AACS Entrez, Source | acetoacetyl-CoA synthetase | 51 | 0.282 | 0.4776 | Yes |
| 4 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 271 | 0.155 | 0.5283 | Yes |
| 5 | PDHA2 | PDHA2 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 2 | 332 | 0.144 | 0.5867 | Yes |
| 6 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 1159 | 0.091 | 0.5642 | Yes |
| 7 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 1212 | 0.089 | 0.5992 | Yes |
| 8 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 1295 | 0.086 | 0.6305 | Yes |
| 9 | HMGCL | HMGCL Entrez, Source | 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria) | 1394 | 0.083 | 0.6592 | Yes |
| 10 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 1528 | 0.079 | 0.6834 | Yes |
| 11 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.7070 | Yes |
| 12 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 2896 | 0.052 | 0.6363 | No |
| 13 | SDS | SDS Entrez, Source | serine dehydratase | 3684 | 0.041 | 0.5949 | No |
| 14 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 4114 | 0.035 | 0.5779 | No |
| 15 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 5156 | 0.022 | 0.5093 | No |
| 16 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5455 | 0.019 | 0.4951 | No |
| 17 | PDHA1 | PDHA1 Entrez, Source | pyruvate dehydrogenase (lipoamide) alpha 1 | 6772 | 0.004 | 0.3982 | No |
| 18 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 7461 | -0.003 | 0.3480 | No |
| 19 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 7949 | -0.009 | 0.3153 | No |
| 20 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 8630 | -0.017 | 0.2717 | No |
| 21 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 9309 | -0.026 | 0.2321 | No |
| 22 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 9511 | -0.029 | 0.2297 | No |
| 23 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 12682 | -0.133 | 0.0495 | No |
