Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CANCER_UNDIFFERENTIATED_META_UP |
| Enrichment Score (ES) | -0.67290837 |
| Normalized Enrichment Score (NES) | -2.0486214 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0051724277 |
| FWER p-Value | 0.108 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 376 | 0.138 | 0.0108 | No |
| 2 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 2001 | 0.068 | -0.0920 | No |
| 3 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 2396 | 0.060 | -0.1046 | No |
| 4 | SSBP1 | SSBP1 Entrez, Source | single-stranded DNA binding protein 1 | 3588 | 0.042 | -0.1823 | No |
| 5 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.2233 | No |
| 6 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4303 | 0.033 | -0.2174 | No |
| 7 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 5403 | 0.019 | -0.2945 | No |
| 8 | ADRM1 | ADRM1 Entrez, Source | adhesion regulating molecule 1 | 5818 | 0.015 | -0.3215 | No |
| 9 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5929 | 0.014 | -0.3259 | No |
| 10 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 6039 | 0.012 | -0.3306 | No |
| 11 | EIF2S2 | EIF2S2 Entrez, Source | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 6160 | 0.011 | -0.3364 | No |
| 12 | CCT6A | CCT6A Entrez, Source | chaperonin containing TCP1, subunit 6A (zeta 1) | 6251 | 0.010 | -0.3403 | No |
| 13 | PSMB7 | PSMB7 Entrez, Source | proteasome (prosome, macropain) subunit, beta type, 7 | 6790 | 0.004 | -0.3795 | No |
| 14 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6894 | 0.003 | -0.3864 | No |
| 15 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 7056 | 0.001 | -0.3981 | No |
| 16 | CTSL | CTSL Entrez, Source | cathepsin L | 8194 | -0.012 | -0.4802 | No |
| 17 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8388 | -0.014 | -0.4908 | No |
| 18 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 9257 | -0.025 | -0.5489 | No |
| 19 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | -0.6035 | No |
| 20 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 10696 | -0.049 | -0.6320 | No |
| 21 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 11241 | -0.061 | -0.6557 | Yes |
| 22 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11253 | -0.061 | -0.6392 | Yes |
| 23 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11267 | -0.062 | -0.6228 | Yes |
| 24 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11780 | -0.078 | -0.6392 | Yes |
| 25 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11841 | -0.081 | -0.6209 | Yes |
| 26 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 11957 | -0.085 | -0.6055 | Yes |
| 27 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12243 | -0.099 | -0.5990 | Yes |
| 28 | TUBB | TUBB Entrez, Source | tubulin, beta | 12364 | -0.108 | -0.5775 | Yes |
| 29 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 12400 | -0.111 | -0.5488 | Yes |
| 30 | GAS6 | GAS6 Entrez, Source | growth arrest-specific 6 | 12538 | -0.120 | -0.5251 | Yes |
| 31 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12798 | -0.147 | -0.5030 | Yes |
| 32 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12895 | -0.164 | -0.4640 | Yes |
| 33 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 12918 | -0.169 | -0.4179 | Yes |
| 34 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | -0.3644 | Yes |
| 35 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13257 | -0.367 | -0.2707 | Yes |
| 36 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | -0.1414 | Yes |
| 37 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13316 | -0.512 | 0.0020 | Yes |
