Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | CARBOHYDRATE_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.39976138 |
| Normalized Enrichment Score (NES) | 1.6899117 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06057469 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FBP1 | FBP1 Entrez, Source | fructose-1,6-bisphosphatase 1 | 67 | 0.255 | 0.0372 | Yes |
| 2 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 127 | 0.202 | 0.0663 | Yes |
| 3 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 207 | 0.172 | 0.0887 | Yes |
| 4 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 218 | 0.170 | 0.1161 | Yes |
| 5 | MIOX | MIOX Entrez, Source | myo-inositol oxygenase | 289 | 0.151 | 0.1358 | Yes |
| 6 | HPSE | HPSE Entrez, Source | heparanase | 311 | 0.148 | 0.1587 | Yes |
| 7 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 370 | 0.139 | 0.1773 | Yes |
| 8 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 476 | 0.127 | 0.1904 | Yes |
| 9 | CARKL | CARKL Entrez, Source | carbohydrate kinase-like | 529 | 0.123 | 0.2069 | Yes |
| 10 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 712 | 0.111 | 0.2115 | Yes |
| 11 | EPM2A | EPM2A Entrez, Source | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 756 | 0.109 | 0.2263 | Yes |
| 12 | INSR | INSR Entrez, Source | insulin receptor | 772 | 0.108 | 0.2430 | Yes |
| 13 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 790 | 0.107 | 0.2595 | Yes |
| 14 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 900 | 0.102 | 0.2682 | Yes |
| 15 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 941 | 0.100 | 0.2817 | Yes |
| 16 | SLC2A5 | SLC2A5 Entrez, Source | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 1059 | 0.095 | 0.2886 | Yes |
| 17 | PDHB | PDHB Entrez, Source | pyruvate dehydrogenase (lipoamide) beta | 1159 | 0.091 | 0.2962 | Yes |
| 18 | B3GAT1 | B3GAT1 Entrez, Source | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | 1172 | 0.090 | 0.3102 | Yes |
| 19 | NDST1 | NDST1 Entrez, Source | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 1207 | 0.089 | 0.3225 | Yes |
| 20 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 1212 | 0.089 | 0.3370 | Yes |
| 21 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 1441 | 0.081 | 0.3332 | Yes |
| 22 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | 0.3425 | Yes |
| 23 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1562 | 0.078 | 0.3503 | Yes |
| 24 | CHST3 | CHST3 Entrez, Source | carbohydrate (chondroitin 6) sulfotransferase 3 | 1564 | 0.078 | 0.3631 | Yes |
| 25 | FUT1 | FUT1 Entrez, Source | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 1575 | 0.078 | 0.3752 | Yes |
| 26 | TFF1 | TFF1 Entrez, Source | trefoil factor 1 (breast cancer, estrogen-inducible sequence expressed in) | 1667 | 0.075 | 0.3808 | Yes |
| 27 | NANP | NANP Entrez, Source | N-acetylneuraminic acid phosphatase | 1668 | 0.075 | 0.3932 | Yes |
| 28 | ACN9 | ACN9 Entrez, Source | ACN9 homolog (S. cerevisiae) | 1743 | 0.073 | 0.3998 | Yes |
| 29 | LALBA | LALBA Entrez, Source | lactalbumin, alpha- | 1989 | 0.068 | 0.3926 | No |
| 30 | GALNT7 | GALNT7 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) | 2182 | 0.064 | 0.3887 | No |
| 31 | ST6GALNAC6 | ST6GALNAC6 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 | 2360 | 0.061 | 0.3854 | No |
| 32 | LECT1 | LECT1 Entrez, Source | leukocyte cell derived chemotaxin 1 | 2642 | 0.056 | 0.3735 | No |
| 33 | GMDS | GMDS Entrez, Source | GDP-mannose 4,6-dehydratase | 2826 | 0.053 | 0.3684 | No |
| 34 | ST6GAL1 | ST6GAL1 Entrez, Source | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 2963 | 0.051 | 0.3665 | No |
| 35 | B4GALNT1 | B4GALNT1 Entrez, Source | beta-1,4-N-acetyl-galactosaminyl transferase 1 | 2969 | 0.051 | 0.3745 | No |
| 36 | FPGT | FPGT Entrez, Source | fucose-1-phosphate guanylyltransferase | 3376 | 0.045 | 0.3512 | No |
| 37 | GFPT1 | GFPT1 Entrez, Source | glutamine-fructose-6-phosphate transaminase 1 | 3414 | 0.044 | 0.3558 | No |
| 38 | SLC5A2 | SLC5A2 Entrez, Source | solute carrier family 5 (sodium/glucose cotransporter), member 2 | 3530 | 0.043 | 0.3541 | No |
| 39 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3579 | 0.042 | 0.3574 | No |
| 40 | PYGM | PYGM Entrez, Source | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | 3629 | 0.041 | 0.3606 | No |
| 41 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 3630 | 0.041 | 0.3674 | No |
| 42 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 3799 | 0.039 | 0.3612 | No |
| 43 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 3953 | 0.037 | 0.3558 | No |
| 44 | ST8SIA5 | ST8SIA5 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 | 4130 | 0.035 | 0.3483 | No |
| 45 | SLC2A8 | SLC2A8 Entrez, Source | solute carrier family 2, (facilitated glucose transporter) member 8 | 4352 | 0.032 | 0.3369 | No |
| 46 | GFPT2 | GFPT2 Entrez, Source | glutamine-fructose-6-phosphate transaminase 2 | 4497 | 0.030 | 0.3310 | No |
| 47 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 4526 | 0.030 | 0.3338 | No |
| 48 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 4559 | 0.029 | 0.3362 | No |
| 49 | PTEN | PTEN Entrez, Source | phosphatase and tensin homolog (mutated in multiple advanced cancers 1) | 4572 | 0.029 | 0.3401 | No |
| 50 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 4655 | 0.028 | 0.3386 | No |
| 51 | ST8SIA1 | ST8SIA1 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 4799 | 0.026 | 0.3321 | No |
| 52 | NEU3 | NEU3 Entrez, Source | sialidase 3 (membrane sialidase) | 4971 | 0.024 | 0.3232 | No |
| 53 | XYLT1 | XYLT1 Entrez, Source | xylosyltransferase I | 5029 | 0.023 | 0.3228 | No |
| 54 | ADRB3 | ADRB3 Entrez, Source | adrenergic, beta-3-, receptor | 5128 | 0.022 | 0.3191 | No |
| 55 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 5418 | 0.019 | 0.3004 | No |
| 56 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5455 | 0.019 | 0.3008 | No |
| 57 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 5522 | 0.018 | 0.2988 | No |
| 58 | TALDO1 | TALDO1 Entrez, Source | transaldolase 1 | 5840 | 0.014 | 0.2772 | No |
| 59 | HK1 | HK1 Entrez, Source | hexokinase 1 | 5904 | 0.014 | 0.2748 | No |
| 60 | TREH | TREH Entrez, Source | trehalase (brush-border membrane glycoprotein) | 5920 | 0.014 | 0.2759 | No |
| 61 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 6092 | 0.012 | 0.2650 | No |
| 62 | B3GAT2 | B3GAT2 Entrez, Source | beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) | 6194 | 0.011 | 0.2591 | No |
| 63 | MPDU1 | MPDU1 Entrez, Source | mannose-P-dolichol utilization defect 1 | 6280 | 0.010 | 0.2544 | No |
| 64 | CHST12 | CHST12 Entrez, Source | carbohydrate (chondroitin 4) sulfotransferase 12 | 6349 | 0.009 | 0.2507 | No |
| 65 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 6404 | 0.008 | 0.2481 | No |
| 66 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 6549 | 0.007 | 0.2383 | No |
| 67 | ST8SIA2 | ST8SIA2 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 6554 | 0.007 | 0.2392 | No |
| 68 | IPPK | IPPK Entrez, Source | inositol 1,3,4,5,6-pentakisphosphate 2-kinase | 6623 | 0.006 | 0.2351 | No |
| 69 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 6630 | 0.006 | 0.2356 | No |
| 70 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 6701 | 0.005 | 0.2313 | No |
| 71 | FUT2 | FUT2 Entrez, Source | fucosyltransferase 2 (secretor status included) | 6734 | 0.005 | 0.2297 | No |
| 72 | PIGQ | PIGQ Entrez, Source | phosphatidylinositol glycan anchor biosynthesis, class Q | 6749 | 0.005 | 0.2294 | No |
| 73 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 6869 | 0.003 | 0.2210 | No |
| 74 | ST8SIA4 | ST8SIA4 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 7141 | 0.000 | 0.2006 | No |
| 75 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 7313 | -0.002 | 0.1879 | No |
| 76 | ST3GAL5 | ST3GAL5 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 7369 | -0.002 | 0.1841 | No |
| 77 | FUT8 | FUT8 Entrez, Source | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 7725 | -0.006 | 0.1583 | No |
| 78 | XYLB | XYLB Entrez, Source | xylulokinase homolog (H. influenzae) | 7766 | -0.007 | 0.1564 | No |
| 79 | GALNT5 | GALNT5 Entrez, Source | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5) | 7975 | -0.009 | 0.1422 | No |
| 80 | FUT4 | FUT4 Entrez, Source | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) | 8286 | -0.013 | 0.1209 | No |
| 81 | PDK1 | PDK1 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 1 | 8304 | -0.013 | 0.1218 | No |
| 82 | IL17F | IL17F Entrez, Source | interleukin 17F | 8354 | -0.014 | 0.1203 | No |
| 83 | B4GALT7 | B4GALT7 Entrez, Source | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) | 8468 | -0.015 | 0.1143 | No |
| 84 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 8630 | -0.017 | 0.1050 | No |
| 85 | UGP2 | UGP2 Entrez, Source | UDP-glucose pyrophosphorylase 2 | 8944 | -0.021 | 0.0849 | No |
| 86 | SLC35A3 | SLC35A3 Entrez, Source | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 8981 | -0.022 | 0.0857 | No |
| 87 | ARPP-19 | ARPP-19 Entrez, Source | - | 8985 | -0.022 | 0.0891 | No |
| 88 | FUT9 | FUT9 Entrez, Source | fucosyltransferase 9 (alpha (1,3) fucosyltransferase) | 9168 | -0.024 | 0.0793 | No |
| 89 | ST3GAL6 | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 9231 | -0.025 | 0.0787 | No |
| 90 | POMT1 | POMT1 Entrez, Source | protein-O-mannosyltransferase 1 | 9373 | -0.027 | 0.0726 | No |
| 91 | ST6GAL2 | ST6GAL2 Entrez, Source | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 9394 | -0.027 | 0.0756 | No |
| 92 | GALK1 | GALK1 Entrez, Source | galactokinase 1 | 9799 | -0.033 | 0.0506 | No |
| 93 | CHST1 | CHST1 Entrez, Source | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 10266 | -0.041 | 0.0221 | No |
| 94 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 10491 | -0.045 | 0.0127 | No |
| 95 | PYGB | PYGB Entrez, Source | phosphorylase, glycogen; brain | 10620 | -0.047 | 0.0108 | No |
| 96 | ST8SIA3 | ST8SIA3 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 | 10869 | -0.053 | 0.0009 | No |
| 97 | EXTL2 | EXTL2 Entrez, Source | exostoses (multiple)-like 2 | 10968 | -0.055 | 0.0026 | No |
| 98 | CHIA | CHIA Entrez, Source | chitinase, acidic | 11088 | -0.058 | 0.0032 | No |
| 99 | GAA | GAA Entrez, Source | glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) | 11222 | -0.061 | 0.0032 | No |
| 100 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 11295 | -0.062 | 0.0080 | No |
| 101 | GNS | GNS Entrez, Source | glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) | 11302 | -0.062 | 0.0179 | No |
| 102 | NAGK | NAGK Entrez, Source | N-acetylglucosamine kinase | 11479 | -0.068 | 0.0158 | No |
| 103 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11670 | -0.074 | 0.0138 | No |
| 104 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 11945 | -0.085 | 0.0071 | No |
| 105 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 12126 | -0.093 | 0.0089 | No |
| 106 | GUSB | GUSB Entrez, Source | glucuronidase, beta | 12176 | -0.096 | 0.0210 | No |
| 107 | MGAT1 | MGAT1 Entrez, Source | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 12474 | -0.116 | 0.0177 | No |
| 108 | ST3GAL2 | ST3GAL2 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 | 13192 | -0.289 | 0.0113 | No |
