Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | CARBON_CARBON_LYASE_ACTIVITY |
| Enrichment Score (ES) | 0.6638265 |
| Normalized Enrichment Score (NES) | 1.8787575 |
| Nominal p-value | 0.0065502184 |
| FDR q-value | 0.018034402 |
| FWER p-Value | 0.627 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 21 | 0.352 | 0.2260 | Yes |
| 2 | HACL1 | HACL1 Entrez, Source | 2-hydroxyacyl-CoA lyase 1 | 94 | 0.229 | 0.3685 | Yes |
| 3 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 148 | 0.193 | 0.4893 | Yes |
| 4 | HDC | HDC Entrez, Source | histidine decarboxylase | 383 | 0.138 | 0.5609 | Yes |
| 5 | ACMSD | ACMSD Entrez, Source | aminocarboxymuconate semialdehyde decarboxylase | 514 | 0.124 | 0.6313 | Yes |
| 6 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 941 | 0.100 | 0.6638 | Yes |
| 7 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 2252 | 0.063 | 0.6062 | No |
| 8 | MLYCD | MLYCD Entrez, Source | malonyl-CoA decarboxylase | 2302 | 0.062 | 0.6426 | No |
| 9 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 3912 | 0.038 | 0.5462 | No |
| 10 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 4001 | 0.036 | 0.5631 | No |
| 11 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 4512 | 0.030 | 0.5442 | No |
| 12 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5455 | 0.019 | 0.4856 | No |
| 13 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 5628 | 0.017 | 0.4835 | No |
| 14 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 5821 | 0.015 | 0.4786 | No |
| 15 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 6404 | 0.008 | 0.4404 | No |
| 16 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 7596 | -0.005 | 0.3541 | No |
| 17 | UROD | UROD Entrez, Source | uroporphyrinogen decarboxylase | 9864 | -0.034 | 0.2061 | No |
| 18 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 11945 | -0.085 | 0.1048 | No |
