Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CARIES_PULP_DN |
| Enrichment Score (ES) | -0.5524805 |
| Normalized Enrichment Score (NES) | -1.7467635 |
| Nominal p-value | 0.008503402 |
| FDR q-value | 0.050335128 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPON1 | SPON1 Entrez, Source | spondin 1, extracellular matrix protein | 176 | 0.182 | 0.0264 | No |
| 2 | GPC3 | GPC3 Entrez, Source | glypican 3 | 221 | 0.167 | 0.0594 | No |
| 3 | COL5A3 | COL5A3 Entrez, Source | collagen, type V, alpha 3 | 285 | 0.151 | 0.0876 | No |
| 4 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 546 | 0.122 | 0.0946 | No |
| 5 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 873 | 0.104 | 0.0927 | No |
| 6 | DPP6 | DPP6 Entrez, Source | dipeptidyl-peptidase 6 | 1178 | 0.090 | 0.0895 | No |
| 7 | GHR | GHR Entrez, Source | growth hormone receptor | 1215 | 0.089 | 0.1062 | No |
| 8 | PLCL1 | PLCL1 Entrez, Source | phospholipase C-like 1 | 1637 | 0.076 | 0.0911 | No |
| 9 | DSPP | DSPP Entrez, Source | dentin sialophosphoprotein | 2365 | 0.061 | 0.0496 | No |
| 10 | MAGI2 | MAGI2 Entrez, Source | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 2940 | 0.051 | 0.0176 | No |
| 11 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 3666 | 0.041 | -0.0280 | No |
| 12 | GAP43 | GAP43 Entrez, Source | growth associated protein 43 | 3808 | 0.039 | -0.0301 | No |
| 13 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 3836 | 0.039 | -0.0237 | No |
| 14 | LGR4 | LGR4 Entrez, Source | leucine-rich repeat-containing G protein-coupled receptor 4 | 4294 | 0.033 | -0.0509 | No |
| 15 | CALB1 | CALB1 Entrez, Source | calbindin 1, 28kDa | 4543 | 0.030 | -0.0632 | No |
| 16 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 4640 | 0.028 | -0.0642 | No |
| 17 | SLIT2 | SLIT2 Entrez, Source | slit homolog 2 (Drosophila) | 4685 | 0.028 | -0.0615 | No |
| 18 | ST8SIA1 | ST8SIA1 Entrez, Source | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | 4799 | 0.026 | -0.0643 | No |
| 19 | NRXN1 | NRXN1 Entrez, Source | neurexin 1 | 5290 | 0.020 | -0.0967 | No |
| 20 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 6064 | 0.012 | -0.1522 | No |
| 21 | PLK2 | PLK2 Entrez, Source | polo-like kinase 2 (Drosophila) | 6290 | 0.010 | -0.1670 | No |
| 22 | PER3 | PER3 Entrez, Source | period homolog 3 (Drosophila) | 6610 | 0.006 | -0.1895 | No |
| 23 | CA2 | CA2 Entrez, Source | carbonic anhydrase II | 7034 | 0.002 | -0.2210 | No |
| 24 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 7463 | -0.003 | -0.2525 | No |
| 25 | PDZD2 | PDZD2 Entrez, Source | PDZ domain containing 2 | 8263 | -0.013 | -0.3098 | No |
| 26 | ATP1A2 | ATP1A2 Entrez, Source | ATPase, Na+/K+ transporting, alpha 2 (+) polypeptide | 8683 | -0.018 | -0.3375 | No |
| 27 | GPR64 | GPR64 Entrez, Source | G protein-coupled receptor 64 | 9010 | -0.022 | -0.3572 | No |
| 28 | OSR2 | OSR2 Entrez, Source | odd-skipped related 2 (Drosophila) | 9457 | -0.028 | -0.3846 | No |
| 29 | DMP1 | DMP1 Entrez, Source | dentin matrix acidic phosphoprotein | 9727 | -0.032 | -0.3977 | No |
| 30 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 9974 | -0.036 | -0.4083 | No |
| 31 | NAP1L3 | NAP1L3 Entrez, Source | nucleosome assembly protein 1-like 3 | 10240 | -0.040 | -0.4195 | No |
| 32 | PER2 | PER2 Entrez, Source | period homolog 2 (Drosophila) | 10374 | -0.043 | -0.4201 | No |
| 33 | CRYZ | CRYZ Entrez, Source | crystallin, zeta (quinone reductase) | 12135 | -0.093 | -0.5322 | Yes |
| 34 | TRPC1 | TRPC1 Entrez, Source | transient receptor potential cation channel, subfamily C, member 1 | 12347 | -0.107 | -0.5247 | Yes |
| 35 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 12549 | -0.121 | -0.5134 | Yes |
| 36 | CYR61 | CYR61 Entrez, Source | cysteine-rich, angiogenic inducer, 61 | 12557 | -0.122 | -0.4874 | Yes |
| 37 | OMD | OMD Entrez, Source | osteomodulin | 12644 | -0.129 | -0.4658 | Yes |
| 38 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12750 | -0.141 | -0.4430 | Yes |
| 39 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 12840 | -0.154 | -0.4162 | Yes |
| 40 | GPM6A | GPM6A Entrez, Source | glycoprotein M6A | 13085 | -0.224 | -0.3858 | Yes |
| 41 | CPE | CPE Entrez, Source | carboxypeptidase E | 13284 | -0.413 | -0.3108 | Yes |
| 42 | DIO3 | DIO3 Entrez, Source | deiodinase, iodothyronine, type III | 13306 | -0.477 | -0.2086 | Yes |
| 43 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13307 | -0.479 | -0.1043 | Yes |
| 44 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13311 | -0.491 | 0.0023 | Yes |
