Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CELL_CYCLE_CHECKPOINT |
| Enrichment Score (ES) | -0.74757665 |
| Normalized Enrichment Score (NES) | -1.8819501 |
| Nominal p-value | 0.0018621974 |
| FDR q-value | 0.025851356 |
| FWER p-Value | 0.727 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RAD17 | RAD17 Entrez, Source | RAD17 homolog (S. pombe) | 4815 | 0.026 | -0.3437 | No |
| 2 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 5173 | 0.022 | -0.3559 | No |
| 3 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.3416 | No |
| 4 | MRE11A | MRE11A Entrez, Source | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 5387 | 0.019 | -0.3442 | No |
| 5 | LCMT2 | LCMT2 Entrez, Source | leucine carboxyl methyltransferase 2 | 8774 | -0.019 | -0.5855 | No |
| 6 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 9318 | -0.026 | -0.6087 | No |
| 7 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.6102 | No |
| 8 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 10001 | -0.037 | -0.6146 | No |
| 9 | CHEK2 | CHEK2 Entrez, Source | CHK2 checkpoint homolog (S. pombe) | 10020 | -0.037 | -0.5911 | No |
| 10 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.6861 | Yes |
| 11 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12271 | -0.101 | -0.6306 | Yes |
| 12 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 12787 | -0.146 | -0.5713 | Yes |
| 13 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12915 | -0.168 | -0.4679 | Yes |
| 14 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 13175 | -0.275 | -0.3025 | Yes |
| 15 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | 0.0031 | Yes |
