Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CELL_PROJECTION |
| Enrichment Score (ES) | -0.5356532 |
| Normalized Enrichment Score (NES) | -1.8203797 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.03812092 |
| FWER p-Value | 0.939 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SI | SI Entrez, Source | sucrase-isomaltase (alpha-glucosidase) | 137 | 0.197 | 0.0350 | No |
| 2 | PDPN | PDPN Entrez, Source | podoplanin | 1510 | 0.079 | -0.0502 | No |
| 3 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 1803 | 0.072 | -0.0557 | No |
| 4 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 1995 | 0.068 | -0.0544 | No |
| 5 | CACNA1A | CACNA1A Entrez, Source | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 3318 | 0.046 | -0.1435 | No |
| 6 | AKAP4 | AKAP4 Entrez, Source | A kinase (PRKA) anchor protein 4 | 3589 | 0.042 | -0.1543 | No |
| 7 | ABI3 | ABI3 Entrez, Source | ABI gene family, member 3 | 3935 | 0.037 | -0.1717 | No |
| 8 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 4226 | 0.033 | -0.1858 | No |
| 9 | SYNPO | SYNPO Entrez, Source | synaptopodin | 4486 | 0.030 | -0.1984 | No |
| 10 | ESPN | ESPN Entrez, Source | espin | 4739 | 0.027 | -0.2112 | No |
| 11 | USH1C | USH1C Entrez, Source | Usher syndrome 1C (autosomal recessive, severe) | 4755 | 0.027 | -0.2062 | No |
| 12 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4844 | 0.026 | -0.2069 | No |
| 13 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | -0.2406 | No |
| 14 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 5536 | 0.018 | -0.2502 | No |
| 15 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5897 | 0.014 | -0.2741 | No |
| 16 | NME2 | NME2 Entrez, Source | non-metastatic cells 2, protein (NM23B) expressed in | 6108 | 0.012 | -0.2872 | No |
| 17 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 6139 | 0.012 | -0.2868 | No |
| 18 | SLC22A12 | SLC22A12 Entrez, Source | solute carrier family 22 (organic anion/cation transporter), member 12 | 6318 | 0.009 | -0.2981 | No |
| 19 | FGD4 | FGD4 Entrez, Source | FYVE, RhoGEF and PH domain containing 4 | 6756 | 0.005 | -0.3299 | No |
| 20 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6899 | 0.003 | -0.3399 | No |
| 21 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 7052 | 0.001 | -0.3510 | No |
| 22 | DTNBP1 | DTNBP1 Entrez, Source | dystrobrevin binding protein 1 | 7147 | 0.000 | -0.3580 | No |
| 23 | CDH23 | CDH23 Entrez, Source | cadherin-like 23 | 7151 | 0.000 | -0.3581 | No |
| 24 | ARFIP2 | ARFIP2 Entrez, Source | ADP-ribosylation factor interacting protein 2 (arfaptin 2) | 7165 | 0.000 | -0.3590 | No |
| 25 | APBB1 | APBB1 Entrez, Source | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 7884 | -0.008 | -0.4112 | No |
| 26 | FAP | FAP Entrez, Source | fibroblast activation protein, alpha | 8035 | -0.010 | -0.4203 | No |
| 27 | GAS8 | GAS8 Entrez, Source | growth arrest-specific 8 | 8547 | -0.016 | -0.4551 | No |
| 28 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 8604 | -0.017 | -0.4554 | No |
| 29 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 8983 | -0.022 | -0.4789 | No |
| 30 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 9099 | -0.023 | -0.4823 | No |
| 31 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 9127 | -0.023 | -0.4789 | No |
| 32 | MYO5A | MYO5A Entrez, Source | myosin VA (heavy chain 12, myoxin) | 9200 | -0.024 | -0.4787 | No |
| 33 | DFNB31 | DFNB31 Entrez, Source | deafness, autosomal recessive 31 | 9515 | -0.029 | -0.4957 | No |
| 34 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 9801 | -0.033 | -0.5095 | No |
| 35 | CLIC5 | CLIC5 Entrez, Source | chloride intracellular channel 5 | 9815 | -0.034 | -0.5028 | No |
| 36 | TBC1D10A | TBC1D10A Entrez, Source | TBC1 domain family, member 10A | 9832 | -0.034 | -0.4962 | No |
| 37 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 10318 | -0.042 | -0.5232 | Yes |
| 38 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 10393 | -0.043 | -0.5188 | Yes |
| 39 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10521 | -0.046 | -0.5179 | Yes |
| 40 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 10703 | -0.049 | -0.5202 | Yes |
| 41 | TLN1 | TLN1 Entrez, Source | talin 1 | 10840 | -0.052 | -0.5184 | Yes |
| 42 | NEFH | NEFH Entrez, Source | neurofilament, heavy polypeptide 200kDa | 10917 | -0.054 | -0.5117 | Yes |
| 43 | DBNL | DBNL Entrez, Source | drebrin-like | 11132 | -0.059 | -0.5144 | Yes |
| 44 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 11151 | -0.059 | -0.5021 | Yes |
| 45 | CTTN | CTTN Entrez, Source | cortactin | 11597 | -0.072 | -0.5192 | Yes |
| 46 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 11785 | -0.078 | -0.5154 | Yes |
| 47 | FGD1 | FGD1 Entrez, Source | FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia) | 11895 | -0.083 | -0.5045 | Yes |
| 48 | CDH13 | CDH13 Entrez, Source | cadherin 13, H-cadherin (heart) | 11996 | -0.087 | -0.4922 | Yes |
| 49 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12120 | -0.093 | -0.4803 | Yes |
| 50 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12376 | -0.109 | -0.4744 | Yes |
| 51 | BCAR1 | BCAR1 Entrez, Source | breast cancer anti-estrogen resistance 1 | 12497 | -0.117 | -0.4566 | Yes |
| 52 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 12514 | -0.118 | -0.4307 | Yes |
| 53 | CDK5 | CDK5 Entrez, Source | cyclin-dependent kinase 5 | 12579 | -0.124 | -0.4071 | Yes |
| 54 | PPT1 | PPT1 Entrez, Source | palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile) | 12619 | -0.127 | -0.3810 | Yes |
| 55 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12842 | -0.155 | -0.3622 | Yes |
| 56 | MYO1C | MYO1C Entrez, Source | myosin IC | 12992 | -0.186 | -0.3307 | Yes |
| 57 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 13042 | -0.204 | -0.2876 | Yes |
| 58 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13163 | -0.267 | -0.2353 | Yes |
| 59 | CLIC1 | CLIC1 Entrez, Source | chloride intracellular channel 1 | 13181 | -0.281 | -0.1723 | Yes |
| 60 | S100A6 | S100A6 Entrez, Source | S100 calcium binding protein A6 | 13234 | -0.331 | -0.1003 | Yes |
| 61 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | 0.0029 | Yes |
