Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CHANG_SERUM_RESPONSE_UP |
| Enrichment Score (ES) | -0.54329026 |
| Normalized Enrichment Score (NES) | -1.9724126 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.011766825 |
| FWER p-Value | 0.316 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GNG11 | GNG11 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 11 | 35 | 0.306 | 0.0334 | No |
| 2 | PLG | PLG Entrez, Source | plasminogen | 120 | 0.206 | 0.0513 | No |
| 3 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 376 | 0.138 | 0.0484 | No |
| 4 | SRM | SRM Entrez, Source | spermidine synthase | 434 | 0.131 | 0.0595 | No |
| 5 | PTS | PTS Entrez, Source | 6-pyruvoyltetrahydropterin synthase | 877 | 0.104 | 0.0384 | No |
| 6 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 883 | 0.103 | 0.0502 | No |
| 7 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 1392 | 0.083 | 0.0216 | No |
| 8 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 1958 | 0.069 | -0.0129 | No |
| 9 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 2122 | 0.065 | -0.0175 | No |
| 10 | FLNC | FLNC Entrez, Source | filamin C, gamma (actin binding protein 280) | 2361 | 0.061 | -0.0283 | No |
| 11 | NUP107 | NUP107 Entrez, Source | nucleoporin 107kDa | 2504 | 0.058 | -0.0322 | No |
| 12 | IMP4 | IMP4 Entrez, Source | IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) | 2835 | 0.053 | -0.0509 | No |
| 13 | GPLD1 | GPLD1 Entrez, Source | glycosylphosphatidylinositol specific phospholipase D1 | 2945 | 0.051 | -0.0531 | No |
| 14 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 3017 | 0.050 | -0.0526 | No |
| 15 | EBNA1BP2 | EBNA1BP2 Entrez, Source | EBNA1 binding protein 2 | 3279 | 0.046 | -0.0669 | No |
| 16 | RPN1 | RPN1 Entrez, Source | ribophorin I | 3301 | 0.046 | -0.0631 | No |
| 17 | TOMM40 | TOMM40 Entrez, Source | translocase of outer mitochondrial membrane 40 homolog (yeast) | 3471 | 0.043 | -0.0707 | No |
| 18 | SSR3 | SSR3 Entrez, Source | signal sequence receptor, gamma (translocon-associated protein gamma) | 3557 | 0.042 | -0.0722 | No |
| 19 | SNRPA | SNRPA Entrez, Source | small nuclear ribonucleoprotein polypeptide A | 3596 | 0.042 | -0.0701 | No |
| 20 | RUVBL1 | RUVBL1 Entrez, Source | RuvB-like 1 (E. coli) | 3670 | 0.041 | -0.0708 | No |
| 21 | SLC25A5 | SLC25A5 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | 3958 | 0.037 | -0.0881 | No |
| 22 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 4001 | 0.036 | -0.0870 | No |
| 23 | DCLRE1B | DCLRE1B Entrez, Source | DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae) | 4187 | 0.034 | -0.0970 | No |
| 24 | MRPL12 | MRPL12 Entrez, Source | mitochondrial ribosomal protein L12 | 4897 | 0.025 | -0.1476 | No |
| 25 | COX17 | COX17 Entrez, Source | COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) | 4970 | 0.024 | -0.1501 | No |
| 26 | NUTF2 | NUTF2 Entrez, Source | nuclear transport factor 2 | 5297 | 0.020 | -0.1723 | No |
| 27 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 5403 | 0.019 | -0.1780 | No |
| 28 | LYAR | LYAR Entrez, Source | - | 5575 | 0.017 | -0.1889 | No |
| 29 | PCSK7 | PCSK7 Entrez, Source | proprotein convertase subtilisin/kexin type 7 | 5635 | 0.017 | -0.1913 | No |
| 30 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 5763 | 0.015 | -0.1991 | No |
| 31 | HMGB1 | HMGB1 Entrez, Source | high-mobility group box 1 | 6219 | 0.011 | -0.2322 | No |
| 32 | MKKS | MKKS Entrez, Source | McKusick-Kaufman syndrome | 6268 | 0.010 | -0.2346 | No |
| 33 | MRPL37 | MRPL37 Entrez, Source | mitochondrial ribosomal protein L37 | 6494 | 0.008 | -0.2507 | No |
| 34 | MT3 | MT3 Entrez, Source | metallothionein 3 (growth inhibitory factor (neurotrophic)) | 6558 | 0.007 | -0.2547 | No |
| 35 | EMP2 | EMP2 Entrez, Source | epithelial membrane protein 2 | 6612 | 0.006 | -0.2579 | No |
| 36 | RNF138 | RNF138 Entrez, Source | ring finger protein 138 | 6850 | 0.004 | -0.2754 | No |
| 37 | CDCA4 | CDCA4 Entrez, Source | cell division cycle associated 4 | 7119 | 0.001 | -0.2955 | No |
| 38 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7469 | -0.003 | -0.3214 | No |
| 39 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 7569 | -0.005 | -0.3284 | No |
| 40 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 7574 | -0.005 | -0.3281 | No |
| 41 | PSMD12 | PSMD12 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 7695 | -0.006 | -0.3365 | No |
| 42 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 7731 | -0.006 | -0.3384 | No |
| 43 | NUPL1 | NUPL1 Entrez, Source | nucleoporin like 1 | 7785 | -0.007 | -0.3416 | No |
| 44 | PDAP1 | PDAP1 Entrez, Source | PDGFA associated protein 1 | 7929 | -0.009 | -0.3514 | No |
| 45 | MAP3K8 | MAP3K8 Entrez, Source | mitogen-activated protein kinase kinase kinase 8 | 8105 | -0.011 | -0.3634 | No |
| 46 | TXNL2 | TXNL2 Entrez, Source | thioredoxin-like 2 | 8255 | -0.012 | -0.3731 | No |
| 47 | VDAC1 | VDAC1 Entrez, Source | voltage-dependent anion channel 1 | 8265 | -0.013 | -0.3723 | No |
| 48 | CENPJ | CENPJ Entrez, Source | centromere protein J | 8301 | -0.013 | -0.3734 | No |
| 49 | EIF4EBP1 | EIF4EBP1 Entrez, Source | eukaryotic translation initiation factor 4E binding protein 1 | 8352 | -0.014 | -0.3756 | No |
| 50 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 8369 | -0.014 | -0.3752 | No |
| 51 | PSMD2 | PSMD2 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 8388 | -0.014 | -0.3749 | No |
| 52 | SNRPB | SNRPB Entrez, Source | small nuclear ribonucleoprotein polypeptides B and B1 | 9192 | -0.024 | -0.4326 | No |
| 53 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 9384 | -0.027 | -0.4438 | No |
| 54 | PSMA7 | PSMA7 Entrez, Source | proteasome (prosome, macropain) subunit, alpha type, 7 | 9797 | -0.033 | -0.4710 | No |
| 55 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 9823 | -0.034 | -0.4689 | No |
| 56 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 9896 | -0.035 | -0.4703 | No |
| 57 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 10034 | -0.037 | -0.4762 | No |
| 58 | PAICS | PAICS Entrez, Source | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 10082 | -0.038 | -0.4753 | No |
| 59 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 10267 | -0.041 | -0.4843 | No |
| 60 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10319 | -0.042 | -0.4833 | No |
| 61 | DCK | DCK Entrez, Source | deoxycytidine kinase | 10358 | -0.043 | -0.4811 | No |
| 62 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 10526 | -0.046 | -0.4884 | No |
| 63 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 10916 | -0.054 | -0.5114 | No |
| 64 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 10942 | -0.055 | -0.5068 | No |
| 65 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 11046 | -0.057 | -0.5079 | No |
| 66 | NLN | NLN Entrez, Source | neurolysin (metallopeptidase M3 family) | 11516 | -0.069 | -0.5352 | Yes |
| 67 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 11604 | -0.072 | -0.5333 | Yes |
| 68 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 11699 | -0.075 | -0.5315 | Yes |
| 69 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 11780 | -0.078 | -0.5284 | Yes |
| 70 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 11845 | -0.081 | -0.5237 | Yes |
| 71 | RNF41 | RNF41 Entrez, Source | ring finger protein 41 | 11978 | -0.086 | -0.5235 | Yes |
| 72 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.5223 | Yes |
| 73 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 12160 | -0.095 | -0.5152 | Yes |
| 74 | GGH | GGH Entrez, Source | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 12243 | -0.099 | -0.5097 | Yes |
| 75 | TNFRSF12A | TNFRSF12A Entrez, Source | tumor necrosis factor receptor superfamily, member 12A | 12397 | -0.111 | -0.5082 | Yes |
| 76 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 12427 | -0.112 | -0.4972 | Yes |
| 77 | WSB2 | WSB2 Entrez, Source | WD repeat and SOCS box-containing 2 | 12515 | -0.118 | -0.4898 | Yes |
| 78 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 12561 | -0.122 | -0.4789 | Yes |
| 79 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12631 | -0.128 | -0.4690 | Yes |
| 80 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12716 | -0.137 | -0.4592 | Yes |
| 81 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12734 | -0.139 | -0.4442 | Yes |
| 82 | CHEK1 | CHEK1 Entrez, Source | CHK1 checkpoint homolog (S. pombe) | 12915 | -0.168 | -0.4379 | Yes |
| 83 | NUDT1 | NUDT1 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 12918 | -0.169 | -0.4182 | Yes |
| 84 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.4010 | Yes |
| 85 | CKLF | CKLF Entrez, Source | chemokine-like factor | 13010 | -0.190 | -0.3808 | Yes |
| 86 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13025 | -0.196 | -0.3588 | Yes |
| 87 | SMS | SMS Entrez, Source | spermine synthase | 13073 | -0.219 | -0.3366 | Yes |
| 88 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.3106 | Yes |
| 89 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13315 | -0.511 | -0.2575 | Yes |
| 90 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | -0.1970 | Yes |
| 91 | MSN | MSN Entrez, Source | moesin | 13327 | -0.629 | -0.1236 | Yes |
| 92 | TAGLN | TAGLN Entrez, Source | transgelin | 13341 | -1.059 | 0.0001 | Yes |
