Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CHEMICALPATHWAY |
| Enrichment Score (ES) | -0.64535606 |
| Normalized Enrichment Score (NES) | -1.7317415 |
| Nominal p-value | 0.0056710774 |
| FDR q-value | 0.053751286 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4328 | 0.032 | -0.3005 | No |
| 2 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 4579 | 0.029 | -0.2973 | No |
| 3 | EIF2S1 | EIF2S1 Entrez, Source | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | 4657 | 0.028 | -0.2819 | No |
| 4 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 5394 | 0.019 | -0.3225 | No |
| 5 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 6937 | 0.003 | -0.4363 | No |
| 6 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 7310 | -0.002 | -0.4630 | No |
| 7 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 9067 | -0.023 | -0.5776 | No |
| 8 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5953 | No |
| 9 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10281 | -0.041 | -0.6143 | Yes |
| 10 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 10657 | -0.048 | -0.6061 | Yes |
| 11 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10778 | -0.051 | -0.5763 | Yes |
| 12 | TLN1 | TLN1 Entrez, Source | talin 1 | 10840 | -0.052 | -0.5413 | Yes |
| 13 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 10930 | -0.054 | -0.5068 | Yes |
| 14 | BID | BID Entrez, Source | BH3 interacting domain death agonist | 11376 | -0.064 | -0.4915 | Yes |
| 15 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11428 | -0.066 | -0.4453 | Yes |
| 16 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 11446 | -0.066 | -0.3964 | Yes |
| 17 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 11925 | -0.084 | -0.3686 | Yes |
| 18 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.3086 | Yes |
| 19 | PXN | PXN Entrez, Source | paxillin | 12950 | -0.176 | -0.2467 | Yes |
| 20 | APAF1 | APAF1 Entrez, Source | apoptotic peptidase activating factor | 13256 | -0.365 | 0.0065 | Yes |
