Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CMV_24HRS_DN |
| Enrichment Score (ES) | -0.5412689 |
| Normalized Enrichment Score (NES) | -1.7724953 |
| Nominal p-value | 0.006504065 |
| FDR q-value | 0.04680238 |
| FWER p-Value | 0.992 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SULT1E1 | SULT1E1 Entrez, Source | sulfotransferase family 1E, estrogen-preferring, member 1 | 278 | 0.152 | 0.0085 | No |
| 2 | CXCL12 | CXCL12 Entrez, Source | chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) | 295 | 0.150 | 0.0363 | No |
| 3 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 506 | 0.124 | 0.0446 | No |
| 4 | ADRA2A | ADRA2A Entrez, Source | adrenergic, alpha-2A-, receptor | 1280 | 0.087 | 0.0031 | No |
| 5 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 1759 | 0.073 | -0.0187 | No |
| 6 | ANPEP | ANPEP Entrez, Source | alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150) | 1876 | 0.070 | -0.0139 | No |
| 7 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 2001 | 0.068 | -0.0100 | No |
| 8 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 2506 | 0.058 | -0.0367 | No |
| 9 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 2515 | 0.058 | -0.0260 | No |
| 10 | CXCR7 | CXCR7 Entrez, Source | chemokine (C-X-C motif) receptor 7 | 2536 | 0.058 | -0.0163 | No |
| 11 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2629 | 0.056 | -0.0123 | No |
| 12 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 2994 | 0.050 | -0.0301 | No |
| 13 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 3166 | 0.048 | -0.0337 | No |
| 14 | PDGFRA | PDGFRA Entrez, Source | platelet-derived growth factor receptor, alpha polypeptide | 3570 | 0.042 | -0.0559 | No |
| 15 | COL6A2 | COL6A2 Entrez, Source | collagen, type VI, alpha 2 | 3659 | 0.041 | -0.0546 | No |
| 16 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4328 | 0.032 | -0.0987 | No |
| 17 | COL1A1 | COL1A1 Entrez, Source | collagen, type I, alpha 1 | 4462 | 0.030 | -0.1028 | No |
| 18 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 4655 | 0.028 | -0.1118 | No |
| 19 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 4709 | 0.027 | -0.1105 | No |
| 20 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4743 | 0.027 | -0.1078 | No |
| 21 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 6389 | 0.009 | -0.2299 | No |
| 22 | PABPC1 | PABPC1 Entrez, Source | poly(A) binding protein, cytoplasmic 1 | 6465 | 0.008 | -0.2340 | No |
| 23 | TGFBR3 | TGFBR3 Entrez, Source | transforming growth factor, beta receptor III (betaglycan, 300kDa) | 6986 | 0.002 | -0.2727 | No |
| 24 | MATK | MATK Entrez, Source | megakaryocyte-associated tyrosine kinase | 7011 | 0.002 | -0.2742 | No |
| 25 | HIVEP2 | HIVEP2 Entrez, Source | human immunodeficiency virus type I enhancer binding protein 2 | 7700 | -0.006 | -0.3249 | No |
| 26 | COL5A2 | COL5A2 Entrez, Source | collagen, type V, alpha 2 | 7962 | -0.009 | -0.3427 | No |
| 27 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 8017 | -0.010 | -0.3449 | No |
| 28 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 8159 | -0.011 | -0.3534 | No |
| 29 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 8903 | -0.021 | -0.4053 | No |
| 30 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 9384 | -0.027 | -0.4361 | No |
| 31 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 9669 | -0.032 | -0.4514 | No |
| 32 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 10661 | -0.048 | -0.5167 | No |
| 33 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 10706 | -0.050 | -0.5104 | No |
| 34 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 10845 | -0.053 | -0.5106 | No |
| 35 | CHN1 | CHN1 Entrez, Source | chimerin (chimaerin) 1 | 10953 | -0.055 | -0.5081 | No |
| 36 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11206 | -0.060 | -0.5154 | No |
| 37 | EPO | EPO Entrez, Source | erythropoietin | 11309 | -0.063 | -0.5109 | No |
| 38 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11457 | -0.067 | -0.5091 | No |
| 39 | C1R | C1R Entrez, Source | complement component 1, r subcomponent | 11719 | -0.076 | -0.5141 | No |
| 40 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12081 | -0.091 | -0.5237 | Yes |
| 41 | RAB13 | RAB13 Entrez, Source | RAB13, member RAS oncogene family | 12213 | -0.098 | -0.5147 | Yes |
| 42 | SGCG | SGCG Entrez, Source | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 12350 | -0.107 | -0.5042 | Yes |
| 43 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 12523 | -0.119 | -0.4941 | Yes |
| 44 | TSPAN6 | TSPAN6 Entrez, Source | tetraspanin 6 | 12624 | -0.127 | -0.4770 | Yes |
| 45 | HSD17B2 | HSD17B2 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 2 | 12678 | -0.132 | -0.4555 | Yes |
| 46 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12774 | -0.145 | -0.4348 | Yes |
| 47 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.4145 | Yes |
| 48 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 13175 | -0.275 | -0.3759 | Yes |
| 49 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13180 | -0.281 | -0.3220 | Yes |
| 50 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13250 | -0.352 | -0.2592 | Yes |
| 51 | ADM | ADM Entrez, Source | adrenomedullin | 13274 | -0.393 | -0.1849 | Yes |
| 52 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.0938 | Yes |
| 53 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13312 | -0.498 | 0.0023 | Yes |
