Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CROMER_HYPOPHARYNGEAL_MET_VS_NON_DN |
| Enrichment Score (ES) | -0.6869465 |
| Normalized Enrichment Score (NES) | -2.1961393 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0015510649 |
| FWER p-Value | 0.0080 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MALL | MALL Entrez, Source | mal, T-cell differentiation protein-like | 754 | 0.109 | -0.0356 | No |
| 2 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 1958 | 0.069 | -0.1127 | No |
| 3 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2298 | 0.062 | -0.1261 | No |
| 4 | EPAS1 | EPAS1 Entrez, Source | endothelial PAS domain protein 1 | 2672 | 0.056 | -0.1433 | No |
| 5 | AFG3L2 | AFG3L2 Entrez, Source | AFG3 ATPase family gene 3-like 2 (yeast) | 3064 | 0.049 | -0.1632 | No |
| 6 | SDC4 | SDC4 Entrez, Source | syndecan 4 (amphiglycan, ryudocan) | 3132 | 0.048 | -0.1589 | No |
| 7 | PLEC1 | PLEC1 Entrez, Source | plectin 1, intermediate filament binding protein 500kDa | 3180 | 0.048 | -0.1532 | No |
| 8 | VSNL1 | VSNL1 Entrez, Source | visinin-like 1 | 3879 | 0.038 | -0.1983 | No |
| 9 | FLNB | FLNB Entrez, Source | filamin B, beta (actin binding protein 278) | 4024 | 0.036 | -0.2021 | No |
| 10 | KLK10 | KLK10 Entrez, Source | kallikrein 10 | 4140 | 0.035 | -0.2040 | No |
| 11 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 4210 | 0.034 | -0.2027 | No |
| 12 | SMTN | SMTN Entrez, Source | smoothelin | 4596 | 0.029 | -0.2261 | No |
| 13 | HSPA2 | HSPA2 Entrez, Source | heat shock 70kDa protein 2 | 4849 | 0.026 | -0.2400 | No |
| 14 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 5149 | 0.022 | -0.2582 | No |
| 15 | ZC3H8 | ZC3H8 Entrez, Source | zinc finger CCCH-type containing 8 | 5599 | 0.017 | -0.2887 | No |
| 16 | FXYD3 | FXYD3 Entrez, Source | FXYD domain containing ion transport regulator 3 | 6555 | 0.007 | -0.3592 | No |
| 17 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 7712 | -0.006 | -0.4449 | No |
| 18 | ST6GALNAC2 | ST6GALNAC2 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 7740 | -0.006 | -0.4457 | No |
| 19 | SERPINB5 | SERPINB5 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 8500 | -0.016 | -0.4998 | No |
| 20 | VDAC3 | VDAC3 Entrez, Source | voltage-dependent anion channel 3 | 9889 | -0.035 | -0.5974 | No |
| 21 | PPP4C | PPP4C Entrez, Source | protein phosphatase 4 (formerly X), catalytic subunit | 9891 | -0.035 | -0.5908 | No |
| 22 | CKB | CKB Entrez, Source | creatine kinase, brain | 9906 | -0.035 | -0.5850 | No |
| 23 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 9935 | -0.035 | -0.5803 | No |
| 24 | PSMD8 | PSMD8 Entrez, Source | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 10029 | -0.037 | -0.5801 | No |
| 25 | SLC20A2 | SLC20A2 Entrez, Source | solute carrier family 20 (phosphate transporter), member 2 | 10741 | -0.050 | -0.6238 | No |
| 26 | SH3GL1 | SH3GL1 Entrez, Source | SH3-domain GRB2-like 1 | 10765 | -0.051 | -0.6156 | No |
| 27 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 10783 | -0.051 | -0.6070 | No |
| 28 | JUP | JUP Entrez, Source | junction plakoglobin | 10892 | -0.053 | -0.6047 | No |
| 29 | DUSP7 | DUSP7 Entrez, Source | dual specificity phosphatase 7 | 11779 | -0.078 | -0.6562 | No |
| 30 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 11945 | -0.085 | -0.6521 | No |
| 31 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 12409 | -0.112 | -0.6653 | Yes |
| 32 | IMPA2 | IMPA2 Entrez, Source | inositol(myo)-1(or 4)-monophosphatase 2 | 12423 | -0.112 | -0.6445 | Yes |
| 33 | LMNA | LMNA Entrez, Source | lamin A/C | 12554 | -0.122 | -0.6307 | Yes |
| 34 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 12628 | -0.128 | -0.6114 | Yes |
| 35 | DTX2 | DTX2 Entrez, Source | deltex homolog 2 (Drosophila) | 13008 | -0.190 | -0.6030 | Yes |
| 36 | CAV2 | CAV2 Entrez, Source | caveolin 2 | 13140 | -0.252 | -0.5640 | Yes |
| 37 | S100A11 | S100A11 Entrez, Source | S100 calcium binding protein A11 | 13163 | -0.267 | -0.5138 | Yes |
| 38 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13200 | -0.292 | -0.4599 | Yes |
| 39 | GJB3 | GJB3 Entrez, Source | gap junction protein, beta 3, 31kDa (connexin 31) | 13204 | -0.296 | -0.4028 | Yes |
| 40 | TPBG | TPBG Entrez, Source | trophoblast glycoprotein | 13288 | -0.427 | -0.3263 | Yes |
| 41 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 13318 | -0.516 | -0.2284 | Yes |
| 42 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | -0.0000 | Yes |
