Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CROONQUIST_IL6_STROMA_UP |
| Enrichment Score (ES) | -0.5981953 |
| Normalized Enrichment Score (NES) | -1.7113405 |
| Nominal p-value | 0.0034482758 |
| FDR q-value | 0.06247864 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.1976 | No |
| 2 | NOTCH3 | NOTCH3 Entrez, Source | Notch homolog 3 (Drosophila) | 706 | 0.111 | 0.1664 | No |
| 3 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 2001 | 0.068 | 0.0826 | No |
| 4 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 2407 | 0.060 | 0.0639 | No |
| 5 | LOXL1 | LOXL1 Entrez, Source | lysyl oxidase-like 1 | 2447 | 0.060 | 0.0726 | No |
| 6 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 2588 | 0.057 | 0.0732 | No |
| 7 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 4706 | 0.027 | -0.0804 | No |
| 8 | THBS2 | THBS2 Entrez, Source | thrombospondin 2 | 4709 | 0.027 | -0.0752 | No |
| 9 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 5117 | 0.022 | -0.1014 | No |
| 10 | SULF1 | SULF1 Entrez, Source | sulfatase 1 | 5121 | 0.022 | -0.0972 | No |
| 11 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 6791 | 0.004 | -0.2217 | No |
| 12 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.2265 | No |
| 13 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 7645 | -0.005 | -0.2840 | No |
| 14 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 10388 | -0.043 | -0.4815 | No |
| 15 | IER3 | IER3 Entrez, Source | immediate early response 3 | 10439 | -0.044 | -0.4767 | No |
| 16 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 10868 | -0.053 | -0.4984 | No |
| 17 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11206 | -0.060 | -0.5120 | No |
| 18 | GABBR2 | GABBR2 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 2 | 11619 | -0.073 | -0.5287 | No |
| 19 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12081 | -0.091 | -0.5455 | No |
| 20 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 12783 | -0.145 | -0.5698 | Yes |
| 21 | SLC25A4 | SLC25A4 Entrez, Source | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 12996 | -0.187 | -0.5492 | Yes |
| 22 | TMSB4X | TMSB4X Entrez, Source | thymosin, beta 4, X-linked | 13134 | -0.249 | -0.5109 | Yes |
| 23 | LOX | LOX Entrez, Source | lysyl oxidase | 13251 | -0.352 | -0.4509 | Yes |
| 24 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13254 | -0.355 | -0.3817 | Yes |
| 25 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13304 | -0.474 | -0.2928 | Yes |
| 26 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.1984 | Yes |
| 27 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13313 | -0.503 | -0.1004 | Yes |
| 28 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13320 | -0.525 | 0.0017 | Yes |
