Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CYTOSKELETAL_PART |
| Enrichment Score (ES) | -0.5404148 |
| Normalized Enrichment Score (NES) | -2.0178504 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006950839 |
| FWER p-Value | 0.169 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 370 | 0.139 | -0.0106 | No |
| 2 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 402 | 0.135 | 0.0040 | No |
| 3 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 471 | 0.128 | 0.0148 | No |
| 4 | MEFV | MEFV Entrez, Source | Mediterranean fever | 1196 | 0.090 | -0.0287 | No |
| 5 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1428 | 0.082 | -0.0359 | No |
| 6 | CETN1 | CETN1 Entrez, Source | centrin, EF-hand protein, 1 | 1740 | 0.073 | -0.0502 | No |
| 7 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 2024 | 0.067 | -0.0632 | No |
| 8 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 2046 | 0.067 | -0.0564 | No |
| 9 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 2066 | 0.067 | -0.0495 | No |
| 10 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 2145 | 0.065 | -0.0473 | No |
| 11 | KATNA1 | KATNA1 Entrez, Source | katanin p60 (ATPase-containing) subunit A 1 | 2366 | 0.061 | -0.0563 | No |
| 12 | CACNA1C | CACNA1C Entrez, Source | calcium channel, voltage-dependent, L type, alpha 1C subunit | 3252 | 0.046 | -0.1174 | No |
| 13 | MAP1A | MAP1A Entrez, Source | microtubule-associated protein 1A | 3328 | 0.045 | -0.1174 | No |
| 14 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 3550 | 0.042 | -0.1288 | No |
| 15 | AKAP9 | AKAP9 Entrez, Source | A kinase (PRKA) anchor protein (yotiao) 9 | 3978 | 0.037 | -0.1565 | No |
| 16 | MYH7 | MYH7 Entrez, Source | myosin, heavy chain 7, cardiac muscle, beta | 4454 | 0.031 | -0.1886 | No |
| 17 | ESPN | ESPN Entrez, Source | espin | 4739 | 0.027 | -0.2066 | No |
| 18 | DNALI1 | DNALI1 Entrez, Source | dynein, axonemal, light intermediate chain 1 | 4844 | 0.026 | -0.2113 | No |
| 19 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 4979 | 0.024 | -0.2184 | No |
| 20 | GFAP | GFAP Entrez, Source | glial fibrillary acidic protein | 5067 | 0.023 | -0.2221 | No |
| 21 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 5248 | 0.021 | -0.2331 | No |
| 22 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 5334 | 0.020 | -0.2370 | No |
| 23 | ALS2 | ALS2 Entrez, Source | amyotrophic lateral sclerosis 2 (juvenile) | 5536 | 0.018 | -0.2499 | No |
| 24 | TSGA14 | TSGA14 Entrez, Source | testis specific, 14 | 5554 | 0.018 | -0.2490 | No |
| 25 | DYNLL2 | DYNLL2 Entrez, Source | dynein, light chain, LC8-type 2 | 5886 | 0.014 | -0.2723 | No |
| 26 | CETN3 | CETN3 Entrez, Source | centrin, EF-hand protein, 3 (CDC31 homolog, yeast) | 5986 | 0.013 | -0.2781 | No |
| 27 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 6045 | 0.012 | -0.2810 | No |
| 28 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 6130 | 0.012 | -0.2859 | No |
| 29 | TPT1 | TPT1 Entrez, Source | tumor protein, translationally-controlled 1 | 6276 | 0.010 | -0.2956 | No |
| 30 | DCTN1 | DCTN1 Entrez, Source | dynactin 1 (p150, glued homolog, Drosophila) | 6281 | 0.010 | -0.2946 | No |
| 31 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6894 | 0.003 | -0.3405 | No |
| 32 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 6980 | 0.002 | -0.3467 | No |
| 33 | APC | APC Entrez, Source | adenomatosis polyposis coli | 7029 | 0.002 | -0.3501 | No |
| 34 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 7275 | -0.001 | -0.3685 | No |
| 35 | SEPT7 | SEPT7 Entrez, Source | septin 7 | 7371 | -0.002 | -0.3754 | No |
| 36 | ATG4B | ATG4B Entrez, Source | ATG4 autophagy related 4 homolog B (S. cerevisiae) | 7397 | -0.003 | -0.3769 | No |
| 37 | ZW10 | ZW10 Entrez, Source | ZW10, kinetochore associated, homolog (Drosophila) | 7453 | -0.003 | -0.3807 | No |
| 38 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 7525 | -0.004 | -0.3856 | No |
| 39 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 7563 | -0.004 | -0.3878 | No |
| 40 | DYNC1I1 | DYNC1I1 Entrez, Source | dynein, cytoplasmic 1, intermediate chain 1 | 7683 | -0.006 | -0.3961 | No |
| 41 | CDC16 | CDC16 Entrez, Source | CDC16 cell division cycle 16 homolog (S. cerevisiae) | 8030 | -0.010 | -0.4210 | No |
| 42 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 8159 | -0.011 | -0.4293 | No |
| 43 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 8320 | -0.013 | -0.4397 | No |
| 44 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 8327 | -0.013 | -0.4385 | No |
| 45 | TBCE | TBCE Entrez, Source | tubulin-specific chaperone e | 8469 | -0.015 | -0.4472 | No |
| 46 | APPBP2 | APPBP2 Entrez, Source | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 8474 | -0.015 | -0.4456 | No |
| 47 | GAS8 | GAS8 Entrez, Source | growth arrest-specific 8 | 8547 | -0.016 | -0.4491 | No |
| 48 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 8556 | -0.016 | -0.4477 | No |
| 49 | TSC1 | TSC1 Entrez, Source | tuberous sclerosis 1 | 8983 | -0.022 | -0.4772 | No |
| 50 | CDK5RAP2 | CDK5RAP2 Entrez, Source | CDK5 regulatory subunit associated protein 2 | 9003 | -0.022 | -0.4759 | No |
| 51 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 9145 | -0.024 | -0.4836 | No |
| 52 | STAU1 | STAU1 Entrez, Source | staufen, RNA binding protein, homolog 1 (Drosophila) | 9189 | -0.024 | -0.4838 | No |
| 53 | SMC3 | SMC3 Entrez, Source | structural maintenance of chromosomes 3 | 9481 | -0.029 | -0.5022 | No |
| 54 | AURKA | AURKA Entrez, Source | aurora kinase A | 9722 | -0.032 | -0.5162 | No |
| 55 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 9823 | -0.034 | -0.5196 | No |
| 56 | NUDT21 | NUDT21 Entrez, Source | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | 10040 | -0.037 | -0.5312 | No |
| 57 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 10094 | -0.038 | -0.5305 | No |
| 58 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | -0.5283 | No |
| 59 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 10188 | -0.040 | -0.5276 | No |
| 60 | ACTR2 | ACTR2 Entrez, Source | ARP2 actin-related protein 2 homolog (yeast) | 10252 | -0.041 | -0.5273 | No |
| 61 | DRD2 | DRD2 Entrez, Source | dopamine receptor D2 | 10427 | -0.044 | -0.5349 | Yes |
| 62 | PCM1 | PCM1 Entrez, Source | pericentriolar material 1 | 10442 | -0.044 | -0.5305 | Yes |
| 63 | KATNB1 | KATNB1 Entrez, Source | katanin p80 (WD repeat containing) subunit B 1 | 10476 | -0.045 | -0.5274 | Yes |
| 64 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 10526 | -0.046 | -0.5254 | Yes |
| 65 | HDAC6 | HDAC6 Entrez, Source | histone deacetylase 6 | 10578 | -0.047 | -0.5234 | Yes |
| 66 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 10674 | -0.049 | -0.5245 | Yes |
| 67 | CABP1 | CABP1 Entrez, Source | calcium binding protein 1 (calbrain) | 10712 | -0.050 | -0.5211 | Yes |
| 68 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 10742 | -0.050 | -0.5170 | Yes |
| 69 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 10855 | -0.053 | -0.5189 | Yes |
| 70 | CAPZA2 | CAPZA2 Entrez, Source | capping protein (actin filament) muscle Z-line, alpha 2 | 10967 | -0.055 | -0.5204 | Yes |
| 71 | CDC27 | CDC27 Entrez, Source | cell division cycle 27 | 10979 | -0.055 | -0.5143 | Yes |
| 72 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 11030 | -0.056 | -0.5110 | Yes |
| 73 | TPM3 | TPM3 Entrez, Source | tropomyosin 3 | 11062 | -0.057 | -0.5062 | Yes |
| 74 | NDE1 | NDE1 Entrez, Source | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 11073 | -0.057 | -0.4998 | Yes |
| 75 | ACTR1B | ACTR1B Entrez, Source | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | 11168 | -0.060 | -0.4994 | Yes |
| 76 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11253 | -0.061 | -0.4981 | Yes |
| 77 | DCTN2 | DCTN2 Entrez, Source | dynactin 2 (p50) | 11312 | -0.063 | -0.4946 | Yes |
| 78 | SEPT9 | SEPT9 Entrez, Source | septin 9 | 11321 | -0.063 | -0.4874 | Yes |
| 79 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 11326 | -0.063 | -0.4798 | Yes |
| 80 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 11537 | -0.070 | -0.4869 | Yes |
| 81 | ACTR3 | ACTR3 Entrez, Source | ARP3 actin-related protein 3 homolog (yeast) | 11757 | -0.077 | -0.4938 | Yes |
| 82 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 11785 | -0.078 | -0.4861 | Yes |
| 83 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 11845 | -0.081 | -0.4804 | Yes |
| 84 | LASP1 | LASP1 Entrez, Source | LIM and SH3 protein 1 | 11935 | -0.084 | -0.4766 | Yes |
| 85 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 12047 | -0.089 | -0.4738 | Yes |
| 86 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12120 | -0.093 | -0.4677 | Yes |
| 87 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 12221 | -0.098 | -0.4630 | Yes |
| 88 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12275 | -0.102 | -0.4543 | Yes |
| 89 | MYO9B | MYO9B Entrez, Source | myosin IXB | 12453 | -0.114 | -0.4533 | Yes |
| 90 | KIF3C | KIF3C Entrez, Source | kinesin family member 3C | 12478 | -0.116 | -0.4407 | Yes |
| 91 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12486 | -0.117 | -0.4266 | Yes |
| 92 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12487 | -0.117 | -0.4120 | Yes |
| 93 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 12514 | -0.118 | -0.3992 | Yes |
| 94 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 12529 | -0.120 | -0.3853 | Yes |
| 95 | DYNC1LI2 | DYNC1LI2 Entrez, Source | dynein, cytoplasmic 1, light intermediate chain 2 | 12591 | -0.125 | -0.3743 | Yes |
| 96 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 12638 | -0.129 | -0.3617 | Yes |
| 97 | SIRT2 | SIRT2 Entrez, Source | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 12702 | -0.135 | -0.3495 | Yes |
| 98 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 12732 | -0.139 | -0.3344 | Yes |
| 99 | ACTC1 | ACTC1 Entrez, Source | actin, alpha, cardiac muscle 1 | 12741 | -0.140 | -0.3175 | Yes |
| 100 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 12859 | -0.158 | -0.3066 | Yes |
| 101 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12895 | -0.164 | -0.2888 | Yes |
| 102 | PXN | PXN Entrez, Source | paxillin | 12950 | -0.176 | -0.2709 | Yes |
| 103 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.2500 | Yes |
| 104 | MYO1C | MYO1C Entrez, Source | myosin IC | 12992 | -0.186 | -0.2276 | Yes |
| 105 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 13032 | -0.200 | -0.2055 | Yes |
| 106 | VIM | VIM Entrez, Source | vimentin | 13040 | -0.204 | -0.1806 | Yes |
| 107 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 13042 | -0.204 | -0.1551 | Yes |
| 108 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13104 | -0.234 | -0.1305 | Yes |
| 109 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | -0.0000 | Yes |
