Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | CYTOSKELETAL_PROTEIN_BINDING |
| Enrichment Score (ES) | -0.5248477 |
| Normalized Enrichment Score (NES) | -1.8876835 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.025442088 |
| FWER p-Value | 0.699 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 402 | 0.135 | -0.0132 | No |
| 2 | TNNT1 | TNNT1 Entrez, Source | troponin T type 1 (skeletal, slow) | 714 | 0.111 | -0.0226 | No |
| 3 | MEFV | MEFV Entrez, Source | Mediterranean fever | 1196 | 0.090 | -0.0476 | No |
| 4 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1428 | 0.082 | -0.0546 | No |
| 5 | MAPK8IP2 | MAPK8IP2 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 2 | 1589 | 0.077 | -0.0569 | No |
| 6 | TTN | TTN Entrez, Source | titin | 1695 | 0.074 | -0.0554 | No |
| 7 | LRPPRC | LRPPRC Entrez, Source | leucine-rich PPR-motif containing | 1721 | 0.074 | -0.0480 | No |
| 8 | MARCKS | MARCKS Entrez, Source | myristoylated alanine-rich protein kinase C substrate | 1730 | 0.074 | -0.0393 | No |
| 9 | HOOK3 | HOOK3 Entrez, Source | hook homolog 3 (Drosophila) | 1889 | 0.070 | -0.0423 | No |
| 10 | ADD2 | ADD2 Entrez, Source | adducin 2 (beta) | 1897 | 0.070 | -0.0340 | No |
| 11 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 1934 | 0.070 | -0.0279 | No |
| 12 | NRCAM | NRCAM Entrez, Source | neuronal cell adhesion molecule | 1953 | 0.069 | -0.0205 | No |
| 13 | S100B | S100B Entrez, Source | S100 calcium binding protein B | 1995 | 0.068 | -0.0149 | No |
| 14 | TRIM63 | TRIM63 Entrez, Source | tripartite motif-containing 63 | 2150 | 0.065 | -0.0183 | No |
| 15 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 2269 | 0.063 | -0.0193 | No |
| 16 | KATNA1 | KATNA1 Entrez, Source | katanin p60 (ATPase-containing) subunit A 1 | 2366 | 0.061 | -0.0188 | No |
| 17 | TMOD2 | TMOD2 Entrez, Source | tropomodulin 2 (neuronal) | 2592 | 0.057 | -0.0286 | No |
| 18 | SYNE1 | SYNE1 Entrez, Source | spectrin repeat containing, nuclear envelope 1 | 2675 | 0.056 | -0.0277 | No |
| 19 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | -0.0216 | No |
| 20 | GC | GC Entrez, Source | group-specific component (vitamin D binding protein) | 3034 | 0.050 | -0.0414 | No |
| 21 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 3215 | 0.047 | -0.0490 | No |
| 22 | CCR5 | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 3994 | 0.036 | -0.1031 | No |
| 23 | SYNPO | SYNPO Entrez, Source | synaptopodin | 4486 | 0.030 | -0.1363 | No |
| 24 | SMTN | SMTN Entrez, Source | smoothelin | 4596 | 0.029 | -0.1409 | No |
| 25 | ESPN | ESPN Entrez, Source | espin | 4739 | 0.027 | -0.1482 | No |
| 26 | SCIN | SCIN Entrez, Source | scinderin | 4841 | 0.026 | -0.1525 | No |
| 27 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 5334 | 0.020 | -0.1871 | No |
| 28 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 6045 | 0.012 | -0.2391 | No |
| 29 | KIF1B | KIF1B Entrez, Source | kinesin family member 1B | 6130 | 0.012 | -0.2440 | No |
| 30 | HPCA | HPCA Entrez, Source | hippocalcin | 6474 | 0.008 | -0.2689 | No |
| 31 | TARDBP | TARDBP Entrez, Source | TAR DNA binding protein | 6682 | 0.006 | -0.2838 | No |
| 32 | SORBS3 | SORBS3 Entrez, Source | sorbin and SH3 domain containing 3 | 6891 | 0.003 | -0.2991 | No |
| 33 | ANK1 | ANK1 Entrez, Source | ankyrin 1, erythrocytic | 7002 | 0.002 | -0.3072 | No |
| 34 | APC | APC Entrez, Source | adenomatosis polyposis coli | 7029 | 0.002 | -0.3089 | No |
| 35 | APOE | APOE Entrez, Source | apolipoprotein E | 7411 | -0.003 | -0.3373 | No |
| 36 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 7525 | -0.004 | -0.3453 | No |
| 37 | RHCG | RHCG Entrez, Source | Rh family, C glycoprotein | 7539 | -0.004 | -0.3458 | No |
| 38 | DYNC1I1 | DYNC1I1 Entrez, Source | dynein, cytoplasmic 1, intermediate chain 1 | 7683 | -0.006 | -0.3559 | No |
| 39 | MAPK8IP3 | MAPK8IP3 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 3 | 7908 | -0.008 | -0.3717 | No |
| 40 | DLG1 | DLG1 Entrez, Source | discs, large homolog 1 (Drosophila) | 8290 | -0.013 | -0.3988 | No |
| 41 | CENPJ | CENPJ Entrez, Source | centromere protein J | 8301 | -0.013 | -0.3979 | No |
| 42 | POLB | POLB Entrez, Source | polymerase (DNA directed), beta | 8320 | -0.013 | -0.3976 | No |
| 43 | RAE1 | RAE1 Entrez, Source | RAE1 RNA export 1 homolog (S. pombe) | 8525 | -0.016 | -0.4110 | No |
| 44 | ARHGEF2 | ARHGEF2 Entrez, Source | rho/rac guanine nucleotide exchange factor (GEF) 2 | 8556 | -0.016 | -0.4112 | No |
| 45 | ARPC1A | ARPC1A Entrez, Source | actin related protein 2/3 complex, subunit 1A, 41kDa | 8847 | -0.020 | -0.4306 | No |
| 46 | CDK5RAP2 | CDK5RAP2 Entrez, Source | CDK5 regulatory subunit associated protein 2 | 9003 | -0.022 | -0.4395 | No |
| 47 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 9143 | -0.024 | -0.4470 | No |
| 48 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 9145 | -0.024 | -0.4441 | No |
| 49 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 9823 | -0.034 | -0.4909 | No |
| 50 | NCALD | NCALD Entrez, Source | neurocalcin delta | 9924 | -0.035 | -0.4940 | No |
| 51 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 10188 | -0.040 | -0.5088 | No |
| 52 | GABARAPL2 | GABARAPL2 Entrez, Source | GABA(A) receptor-associated protein-like 2 | 10237 | -0.040 | -0.5073 | No |
| 53 | RPH3AL | RPH3AL Entrez, Source | rabphilin 3A-like (without C2 domains) | 10397 | -0.043 | -0.5138 | No |
| 54 | VAPB | VAPB Entrez, Source | VAMP (vesicle-associated membrane protein)-associated protein B and C | 10452 | -0.044 | -0.5123 | No |
| 55 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 10564 | -0.046 | -0.5148 | No |
| 56 | ABRA | ABRA Entrez, Source | actin-binding Rho activating protein | 10602 | -0.047 | -0.5116 | No |
| 57 | KIF5B | KIF5B Entrez, Source | kinesin family member 5B | 10742 | -0.050 | -0.5158 | No |
| 58 | TLN1 | TLN1 Entrez, Source | talin 1 | 10840 | -0.052 | -0.5164 | Yes |
| 59 | JUP | JUP Entrez, Source | junction plakoglobin | 10892 | -0.053 | -0.5135 | Yes |
| 60 | PACSIN3 | PACSIN3 Entrez, Source | protein kinase C and casein kinase substrate in neurons 3 | 10954 | -0.055 | -0.5112 | Yes |
| 61 | NDE1 | NDE1 Entrez, Source | nudE nuclear distribution gene E homolog 1 (A. nidulans) | 11073 | -0.057 | -0.5128 | Yes |
| 62 | TMOD3 | TMOD3 Entrez, Source | tropomodulin 3 (ubiquitous) | 11122 | -0.058 | -0.5090 | Yes |
| 63 | DBNL | DBNL Entrez, Source | drebrin-like | 11132 | -0.059 | -0.5023 | Yes |
| 64 | WASF2 | WASF2 Entrez, Source | WAS protein family, member 2 | 11151 | -0.059 | -0.4961 | Yes |
| 65 | BIRC5 | BIRC5 Entrez, Source | baculoviral IAP repeat-containing 5 (survivin) | 11253 | -0.061 | -0.4960 | Yes |
| 66 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 11326 | -0.063 | -0.4934 | Yes |
| 67 | RHAG | RHAG Entrez, Source | Rh-associated glycoprotein | 11329 | -0.063 | -0.4856 | Yes |
| 68 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 11785 | -0.078 | -0.5100 | Yes |
| 69 | MAPRE1 | MAPRE1 Entrez, Source | microtubule-associated protein, RP/EB family, member 1 | 11845 | -0.081 | -0.5042 | Yes |
| 70 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12120 | -0.093 | -0.5131 | Yes |
| 71 | CAPZB | CAPZB Entrez, Source | capping protein (actin filament) muscle Z-line, beta | 12275 | -0.102 | -0.5119 | Yes |
| 72 | ADD1 | ADD1 Entrez, Source | adducin 1 (alpha) | 12346 | -0.107 | -0.5036 | Yes |
| 73 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12376 | -0.109 | -0.4920 | Yes |
| 74 | MYO9B | MYO9B Entrez, Source | myosin IXB | 12453 | -0.114 | -0.4832 | Yes |
| 75 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12486 | -0.117 | -0.4709 | Yes |
| 76 | BAIAP2 | BAIAP2 Entrez, Source | BAI1-associated protein 2 | 12628 | -0.128 | -0.4654 | Yes |
| 77 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 12638 | -0.129 | -0.4497 | Yes |
| 78 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 12735 | -0.139 | -0.4393 | Yes |
| 79 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12750 | -0.141 | -0.4226 | Yes |
| 80 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12842 | -0.155 | -0.4098 | Yes |
| 81 | PXN | PXN Entrez, Source | paxillin | 12950 | -0.176 | -0.3957 | Yes |
| 82 | ABI2 | ABI2 Entrez, Source | abl interactor 2 | 13075 | -0.221 | -0.3771 | Yes |
| 83 | PRNP | PRNP Entrez, Source | prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia) | 13090 | -0.227 | -0.3495 | Yes |
| 84 | NEXN | NEXN Entrez, Source | nexilin (F actin binding protein) | 13091 | -0.227 | -0.3207 | Yes |
| 85 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 13131 | -0.248 | -0.2923 | Yes |
| 86 | PDLIM5 | PDLIM5 Entrez, Source | PDZ and LIM domain 5 | 13230 | -0.326 | -0.2585 | Yes |
| 87 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | -0.2066 | Yes |
| 88 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.1474 | Yes |
| 89 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13342 | -1.187 | -0.0000 | Yes |
