Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classsingle_gel_48h
GeneSetCYTOSKELETON
Enrichment Score (ES)-0.52450967
Normalized Enrichment Score (NES)-2.078812
Nominal p-value0.0
FDR q-value0.003948635
FWER p-Value0.06
Table: GSEA Results Summary



Fig 1: Enrichment plot: CYTOSKELETON   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1GYS2GYS2
Entrez,  Source
glycogen synthase 2 (liver)3700.139-0.0177No
2ABLIM2ABLIM2
Entrez,  Source
actin binding LIM protein family, member 24000.135-0.0097No
3TNNI3TNNI3
Entrez,  Source
troponin I type 3 (cardiac)4020.1350.0003No
4KIF5AKIF5A
Entrez,  Source
kinesin family member 5A4710.1280.0048No
5NF2NF2
Entrez,  Source
neurofibromin 2 (bilateral acoustic neuroma)10250.096-0.0300No
6MEFVMEFV
Entrez,  Source
Mediterranean fever11960.090-0.0362No
7TNNC1TNNC1
Entrez,  Source
troponin C type 1 (slow)14280.082-0.0476No
8LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing17210.074-0.0642No
9MARCKSMARCKS
Entrez,  Source
myristoylated alanine-rich protein kinase C substrate17300.074-0.0593No
10CETN1CETN1
Entrez,  Source
centrin, EF-hand protein, 117400.073-0.0545No
11CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A19290.070-0.0635No
12DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)19340.070-0.0586No
13UTRNUTRN
Entrez,  Source
utrophin (homologous to dystrophin)19420.069-0.0540No
14AVILAVIL
Entrez,  Source
advillin20210.067-0.0548No
15MYOM1MYOM1
Entrez,  Source
myomesin 1 (skelemin) 185kDa20240.067-0.0499No
16MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)20460.067-0.0465No
17MYH6MYH6
Entrez,  Source
myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)20660.067-0.0429No
18BMFBMF
Entrez,  Source
Bcl2 modifying factor21450.065-0.0440No
19KATNA1KATNA1
Entrez,  Source
katanin p60 (ATPase-containing) subunit A 123660.061-0.0561No
20MYL2MYL2
Entrez,  Source
myosin, light chain 2, regulatory, cardiac, slow27050.055-0.0777No
21STOMSTOM
Entrez,  Source
stomatin30240.050-0.0981No
22STOML2STOML2
Entrez,  Source
stomatin (EPB72)-like 230840.049-0.0989No
23LSP1LSP1
Entrez,  Source
lymphocyte-specific protein 132150.047-0.1052No
24CACNA1CCACNA1C
Entrez,  Source
calcium channel, voltage-dependent, L type, alpha 1C subunit32520.046-0.1045No
25MAP1AMAP1A
Entrez,  Source
microtubule-associated protein 1A33280.045-0.1068No
26SNIPSNIP
Entrez,  Source
-34850.043-0.1154No
27DDX20DDX20
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 2035280.043-0.1154No
28NARFNARF
Entrez,  Source
nuclear prelamin A recognition factor35500.042-0.1138No
29AKAP4AKAP4
Entrez,  Source
A kinase (PRKA) anchor protein 435890.042-0.1136No
30AKAP9AKAP9
Entrez,  Source
A kinase (PRKA) anchor protein (yotiao) 939780.037-0.1403No
31FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)40240.036-0.1410No
32ABCA2ABCA2
Entrez,  Source
ATP-binding cassette, sub-family A (ABC1), member 240270.036-0.1385No
33SLC4A1SLC4A1
Entrez,  Source
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)40600.035-0.1382No
34AMPHAMPH
Entrez,  Source
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)40750.035-0.1366No
35MYH7MYH7
Entrez,  Source
myosin, heavy chain 7, cardiac muscle, beta44540.031-0.1630No
36SYNPOSYNPO
Entrez,  Source
synaptopodin44860.030-0.1631No
37SMTNSMTN
Entrez,  Source
smoothelin45960.029-0.1693No
38ESPNESPN
Entrez,  Source
espin47390.027-0.1780No
39DNALI1DNALI1
Entrez,  Source
dynein, axonemal, light intermediate chain 148440.026-0.1840No
40HINT1HINT1
Entrez,  Source
histidine triad nucleotide binding protein 148530.026-0.1827No
41NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)49790.024-0.1903No
42GFAPGFAP
Entrez,  Source
glial fibrillary acidic protein50670.023-0.1952No
43MYL3MYL3
Entrez,  Source
myosin, light chain 3, alkali; ventricular, skeletal, slow52480.021-0.2073No
44TNNT2TNNT2
Entrez,  Source
troponin T type 2 (cardiac)53340.020-0.2123No
45ALS2ALS2
Entrez,  Source
amyotrophic lateral sclerosis 2 (juvenile)55360.018-0.2262No
46TSGA14TSGA14
Entrez,  Source
testis specific, 1455540.018-0.2262No
47FSCN3FSCN3
Entrez,  Source
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)57940.015-0.2432No
48ACTL7BACTL7B
Entrez,  Source
actin-like 7B58770.014-0.2484No
49DYNLL2DYNLL2
Entrez,  Source
dynein, light chain, LC8-type 258860.014-0.2479No
50CCT3CCT3
Entrez,  Source
chaperonin containing TCP1, subunit 3 (gamma)59540.013-0.2520No
51CETN3CETN3
Entrez,  Source
centrin, EF-hand protein, 3 (CDC31 homolog, yeast)59860.013-0.2534No
52CCNA1CCNA1
Entrez,  Source
cyclin A160190.013-0.2549No
53TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 360450.012-0.2559No
54ARHGDIBARHGDIB
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) beta60800.012-0.2575No
55CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)60860.012-0.2570No
56KIF1BKIF1B
Entrez,  Source
kinesin family member 1B61300.012-0.2594No
57TPT1TPT1
Entrez,  Source
tumor protein, translationally-controlled 162760.010-0.2697No
58DCTN1DCTN1
Entrez,  Source
dynactin 1 (p150, glued homolog, Drosophila)62810.010-0.2692No
59IVLIVL
Entrez,  Source
involucrin64340.008-0.2802No
60MARK1MARK1
Entrez,  Source
MAP/microtubule affinity-regulating kinase 164680.008-0.2821No
61TRPC4TRPC4
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 465320.007-0.2863No
62LYSTLYST
Entrez,  Source
lysosomal trafficking regulator68020.004-0.3064No
63CDC20CDC20
Entrez,  Source
CDC20 cell division cycle 20 homolog (S. cerevisiae)68940.003-0.3131No
64DCTN4DCTN4
Entrez,  Source
dynactin 4 (p62)69800.002-0.3194No
65APCAPC
Entrez,  Source
adenomatosis polyposis coli70290.002-0.3229No
66NUMA1NUMA1
Entrez,  Source
nuclear mitotic apparatus protein 17275-0.001-0.3415No
67HAP1HAP1
Entrez,  Source
huntingtin-associated protein 1 (neuroan 1)7354-0.002-0.3473No
68SEPT7SEPT7
Entrez,  Source
septin 77371-0.002-0.3483No
69ATG4BATG4B
Entrez,  Source
ATG4 autophagy related 4 homolog B (S. cerevisiae)7397-0.003-0.3500No
70ZW10ZW10
Entrez,  Source
ZW10, kinetochore associated, homolog (Drosophila)7453-0.003-0.3540No
71DCXDCX
Entrez,  Source
doublecortex; lissencephaly, X-linked (doublecortin)7525-0.004-0.3590No
72PLK1PLK1
Entrez,  Source
polo-like kinase 1 (Drosophila)7563-0.004-0.3615No
73HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 17586-0.005-0.3628No
74DYNC1I1DYNC1I1
Entrez,  Source
dynein, cytoplasmic 1, intermediate chain 17683-0.006-0.3697No
75CDC16CDC16
Entrez,  Source
CDC16 cell division cycle 16 homolog (S. cerevisiae)8030-0.010-0.3952No
76ARHGDIAARHGDIA
Entrez,  Source
Rho GDP dissociation inhibitor (GDI) alpha8158-0.011-0.4040No
77PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa8159-0.011-0.4032No
78POLBPOLB
Entrez,  Source
polymerase (DNA directed), beta8320-0.013-0.4144No
79CEP57CEP57
Entrez,  Source
centrosomal protein 57kDa8327-0.013-0.4138No
80TBCETBCE
Entrez,  Source
tubulin-specific chaperone e8469-0.015-0.4234No
81APPBP2APPBP2
Entrez,  Source
amyloid beta precursor protein (cytoplasmic tail) binding protein 28474-0.015-0.4226No
82RAE1RAE1
Entrez,  Source
RAE1 RNA export 1 homolog (S. pombe)8525-0.016-0.4252No
83GAS8GAS8
Entrez,  Source
growth arrest-specific 88547-0.016-0.4256No
84ARHGEF2ARHGEF2
Entrez,  Source
rho/rac guanine nucleotide exchange factor (GEF) 28556-0.016-0.4250No
85ARPC1AARPC1A
Entrez,  Source
actin related protein 2/3 complex, subunit 1A, 41kDa8847-0.020-0.4455No
86CDC42BPBCDC42BPB
Entrez,  Source
CDC42 binding protein kinase beta (DMPK-like)8892-0.020-0.4473No
87CTNNB1CTNNB1
Entrez,  Source
catenin (cadherin-associated protein), beta 1, 88kDa8921-0.021-0.4479No
88TSC1TSC1
Entrez,  Source
tuberous sclerosis 18983-0.022-0.4509No
89CDK5RAP2CDK5RAP2
Entrez,  Source
CDK5 regulatory subunit associated protein 29003-0.022-0.4507No
90TUBB2CTUBB2C
Entrez,  Source
tubulin, beta 2C9095-0.023-0.4559No
91CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 29145-0.024-0.4578No
92STAU1STAU1
Entrez,  Source
staufen, RNA binding protein, homolog 1 (Drosophila)9189-0.024-0.4593No
93SMC3SMC3
Entrez,  Source
structural maintenance of chromosomes 39481-0.029-0.4792No
94AURKAAURKA
Entrez,  Source
aurora kinase A9722-0.032-0.4950No
95CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 49801-0.033-0.4984No
96CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 59815-0.034-0.4969No
97BRCA2BRCA2
Entrez,  Source
breast cancer 2, early onset9823-0.034-0.4949No
98NUDT21NUDT21
Entrez,  Source
nudix (nucleoside diphosphate linked moiety X)-type motif 2110040-0.037-0.5085No
99CAPGCAPG
Entrez,  Source
capping protein (actin filament), gelsolin-like10094-0.038-0.5096No
100TOP2ATOP2A
Entrez,  Source
topoisomerase (DNA) II alpha 170kDa10131-0.039-0.5095No
101UXTUXT
Entrez,  Source
ubiquitously-expressed transcript10188-0.040-0.5107No
102GABARAPL2GABARAPL2
Entrez,  Source
GABA(A) receptor-associated protein-like 210237-0.040-0.5113No
103ACTR2ACTR2
Entrez,  Source
ARP2 actin-related protein 2 homolog (yeast)10252-0.041-0.5094No
104DRD2DRD2
Entrez,  Source
dopamine receptor D210427-0.044-0.5193No
105PCM1PCM1
Entrez,  Source
pericentriolar material 110442-0.044-0.5170No
106KATNB1KATNB1
Entrez,  Source
katanin p80 (WD repeat containing) subunit B 110476-0.045-0.5162No
107TUBG1TUBG1
Entrez,  Source
tubulin, gamma 110526-0.046-0.5165No
108HDAC6HDAC6
Entrez,  Source
histone deacetylase 610578-0.047-0.5169No
109ABRAABRA
Entrez,  Source
actin-binding Rho activating protein10602-0.047-0.5151No
110MAP3K11MAP3K11
Entrez,  Source
mitogen-activated protein kinase kinase kinase 1110674-0.049-0.5168No
111CABP1CABP1
Entrez,  Source
calcium binding protein 1 (calbrain)10712-0.050-0.5159No
112KIF5BKIF5B
Entrez,  Source
kinesin family member 5B10742-0.050-0.5143No
113CKAP5CKAP5
Entrez,  Source
cytoskeleton associated protein 510855-0.053-0.5189No
114PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 210930-0.054-0.5204Yes
115CAPZA2CAPZA2
Entrez,  Source
capping protein (actin filament) muscle Z-line, alpha 210967-0.055-0.5190Yes
116CDC27CDC27
Entrez,  Source
cell division cycle 2710979-0.055-0.5157Yes
117KIF4AKIF4A
Entrez,  Source
kinesin family member 4A11030-0.056-0.5153Yes
118TPM3TPM3
Entrez,  Source
tropomyosin 311062-0.057-0.5133Yes
119NDE1NDE1
Entrez,  Source
nudE nuclear distribution gene E homolog 1 (A. nidulans)11073-0.057-0.5098Yes
120WASF2WASF2
Entrez,  Source
WAS protein family, member 211151-0.059-0.5112Yes
121ACTR1BACTR1B
Entrez,  Source
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)11168-0.060-0.5079Yes
122BIRC5BIRC5
Entrez,  Source
baculoviral IAP repeat-containing 5 (survivin)11253-0.061-0.5097Yes
123ACTBACTB
Entrez,  Source
actin, beta11264-0.061-0.5058Yes
124DCTN2DCTN2
Entrez,  Source
dynactin 2 (p50)11312-0.063-0.5047Yes
125HIP1HIP1
Entrez,  Source
huntingtin interacting protein 111319-0.063-0.5004Yes
126SEPT9SEPT9
Entrez,  Source
septin 911321-0.063-0.4958Yes
127SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 411326-0.063-0.4914Yes
128CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase11387-0.065-0.4911Yes
129NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 911537-0.070-0.4971Yes
130CTTNCTTN
Entrez,  Source
cortactin11597-0.072-0.4962Yes
131ACTR3ACTR3
Entrez,  Source
ARP3 actin-related protein 3 homolog (yeast)11757-0.077-0.5025Yes
132MAPTMAPT
Entrez,  Source
microtubule-associated protein tau11785-0.078-0.4987Yes
133MAPRE1MAPRE1
Entrez,  Source
microtubule-associated protein, RP/EB family, member 111845-0.081-0.4971Yes
134CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)11862-0.081-0.4922Yes
135PTPN21PTPN21
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 2111888-0.083-0.4879Yes
136WASLWASL
Entrez,  Source
Wiskott-Aldrich syndrome-like11892-0.083-0.4819Yes
137WASF1WASF1
Entrez,  Source
WAS protein family, member 111932-0.084-0.4785Yes
138LASP1LASP1
Entrez,  Source
LIM and SH3 protein 111935-0.084-0.4723Yes
139ARPC5ARPC5
Entrez,  Source
actin related protein 2/3 complex, subunit 5, 16kDa12047-0.089-0.4741Yes
140SLC9A3R1SLC9A3R1
Entrez,  Source
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 112048-0.089-0.4674Yes
141MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle12120-0.093-0.4658Yes
142DYNLL1DYNLL1
Entrez,  Source
dynein, light chain, LC8-type 112221-0.098-0.4660Yes
143DSPDSP
Entrez,  Source
desmoplakin12225-0.098-0.4589Yes
144GSNGSN
Entrez,  Source
gelsolin (amyloidosis, Finnish type)12230-0.098-0.4518Yes
145CAPZBCAPZB
Entrez,  Source
capping protein (actin filament) muscle Z-line, beta12275-0.102-0.4475Yes
146TUBBTUBB
Entrez,  Source
tubulin, beta12364-0.108-0.4461Yes
147CCNB2CCNB2
Entrez,  Source
cyclin B212396-0.111-0.4401Yes
148BIN1BIN1
Entrez,  Source
bridging integrator 112408-0.112-0.4326Yes
149MYO9BMYO9B
Entrez,  Source
myosin IXB12453-0.114-0.4274Yes
150KIF3CKIF3C
Entrez,  Source
kinesin family member 3C12478-0.116-0.4205Yes
151MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle12486-0.117-0.4123Yes
152MAP1BMAP1B
Entrez,  Source
microtubule-associated protein 1B12487-0.117-0.4035Yes
153NEFLNEFL
Entrez,  Source
neurofilament, light polypeptide 68kDa12514-0.118-0.3966Yes
154KIFC3KIFC3
Entrez,  Source
kinesin family member C312529-0.120-0.3887Yes
155KALRNKALRN
Entrez,  Source
kalirin, RhoGEF kinase12586-0.124-0.3836Yes
156DYNC1LI2DYNC1LI2
Entrez,  Source
dynein, cytoplasmic 1, light intermediate chain 212591-0.125-0.3745Yes
157CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 112638-0.129-0.3684Yes
158SIRT2SIRT2
Entrez,  Source
sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)12702-0.135-0.3630Yes
159ARPC1BARPC1B
Entrez,  Source
actin related protein 2/3 complex, subunit 1B, 41kDa12732-0.139-0.3548Yes
160CALD1CALD1
Entrez,  Source
caldesmon 112735-0.139-0.3445Yes
161ACTC1ACTC1
Entrez,  Source
actin, alpha, cardiac muscle 112741-0.140-0.3344Yes
162SORBS2SORBS2
Entrez,  Source
sorbin and SH3 domain containing 212750-0.141-0.3244Yes
163DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)12762-0.143-0.3145Yes
164TGM1TGM1
Entrez,  Source
transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)12800-0.148-0.3063Yes
165EML2EML2
Entrez,  Source
echinoderm microtubule associated protein like 212859-0.158-0.2988Yes
166KIF2CKIF2C
Entrez,  Source
kinesin family member 2C12895-0.164-0.2892Yes
167PXNPXN
Entrez,  Source
paxillin12950-0.176-0.2801Yes
168TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)12980-0.185-0.2685Yes
169MYO1CMYO1C
Entrez,  Source
myosin IC12992-0.186-0.2553Yes
170TPM4TPM4
Entrez,  Source
tropomyosin 413032-0.200-0.2433Yes
171VIMVIM
Entrez,  Source
vimentin13040-0.204-0.2285Yes
172ACTN3ACTN3
Entrez,  Source
actinin, alpha 313042-0.204-0.2133Yes
173LMNB1LMNB1
Entrez,  Source
lamin B113104-0.234-0.2003Yes
174BASP1BASP1
Entrez,  Source
brain abundant, membrane attached signal protein 113161-0.265-0.1847Yes
175PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513230-0.326-0.1654Yes
176ANXA1ANXA1
Entrez,  Source
annexin A113312-0.498-0.1341Yes
177MSNMSN
Entrez,  Source
moesin13327-0.629-0.0880Yes
178ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle13342-1.1870.0000Yes
Table: GSEA details [plain text format]



Fig 2: CYTOSKELETON   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: CYTOSKELETON: Random ES distribution   
Gene set null distribution of ES for CYTOSKELETON