Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classsingle_gel_48h
GeneSetDIAB_NEPH_DN
Enrichment Score (ES)-0.5300514
Normalized Enrichment Score (NES)-2.1778069
Nominal p-value0.0
FDR q-value0.0016775614
FWER p-Value0.013
Table: GSEA Results Summary



Fig 1: Enrichment plot: DIAB_NEPH_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CYP51A1CYP51A1
Entrez,  Source
cytochrome P450, family 51, subfamily A, polypeptide 1560.2770.0090No
2PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)1480.1930.0113No
3IRS1IRS1
Entrez,  Source
insulin receptor substrate 12330.1630.0126No
4SLKSLK
Entrez,  Source
STE20-like kinase (yeast)3610.1410.0097No
5FGFR2FGFR2
Entrez,  Source
ffer syndrome, Jackson-Weiss syndrome)4190.1330.0117No
6CYP1B1CYP1B1
Entrez,  Source
cytochrome P450, family 1, subfamily B, polypeptide 15060.1240.0111No
7HSPA5HSPA5
Entrez,  Source
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)5670.1200.0122No
8CASP1CASP1
Entrez,  Source
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)8090.106-0.0011No
9KLK7KLK7
Entrez,  Source
kallikrein 7 (chymotryptic, stratum corneum)8570.1050.0003No
10PPFIA4PPFIA4
Entrez,  Source
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 49260.101-0.0000No
11PBEF1PBEF1
Entrez,  Source
pre-B-cell colony enhancing factor 110740.094-0.0067No
12DPP6DPP6
Entrez,  Source
dipeptidyl-peptidase 611780.090-0.0103No
13ITGB5ITGB5
Entrez,  Source
integrin, beta 511940.090-0.0071No
14GHRGHR
Entrez,  Source
growth hormone receptor12150.089-0.0044No
15ACSL3ACSL3
Entrez,  Source
acyl-CoA synthetase long-chain family member 312400.088-0.0020No
16TRIM23TRIM23
Entrez,  Source
tripartite motif-containing 2313240.085-0.0043No
17GNEGNE
Entrez,  Source
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase14410.081-0.0092No
18CMAHCMAH
Entrez,  Source
cytidine monophosphate-N-acetylneuraminic acid hydroxylase (CMP-N-acetylneuraminate monooxygenase)16160.077-0.0188No
19UBE2D2UBE2D2
Entrez,  Source
ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)16700.075-0.0193No
20FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES16820.075-0.0166No
21DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 917490.073-0.0181No
22VEGFVEGF
Entrez,  Source
vascular endothelial growth factor18830.070-0.0249No
23KLK6KLK6
Entrez,  Source
kallikrein 6 (neurosin, zyme)19010.070-0.0228No
24SDC2SDC2
Entrez,  Source
syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan)21390.065-0.0378No
25TOB1TOB1
Entrez,  Source
transducer of ERBB2, 121580.065-0.0361No
26PTPN7PTPN7
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 721810.064-0.0347No
27TSPYL4TSPYL4
Entrez,  Source
TSPY-like 423080.062-0.0414No
28UNGUNG
Entrez,  Source
uracil-DNA glycosylase23740.061-0.0434No
29LOXL1LOXL1
Entrez,  Source
lysyl oxidase-like 124470.060-0.0461No
30PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O24520.059-0.0435No
31APODAPOD
Entrez,  Source
apolipoprotein D25500.058-0.0482No
32SACM1LSACM1L
Entrez,  Source
SAC1 suppressor of actin mutations 1-like (yeast)25570.058-0.0459No
33NDNNDN
Entrez,  Source
necdin homolog (mouse)25730.057-0.0443No
34GMFBGMFB
Entrez,  Source
glia maturation factor, beta25950.057-0.0432No
35CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 225990.057-0.0407No
36GMDSGMDS
Entrez,  Source
GDP-mannose 4,6-dehydratase28260.053-0.0554No
37AKAP11AKAP11
Entrez,  Source
A kinase (PRKA) anchor protein 1128410.053-0.0540No
38MAGI2MAGI2
Entrez,  Source
membrane associated guanylate kinase, WW and PDZ domain containing 229400.051-0.0590No
39HNRPA1HNRPA1
Entrez,  Source
heterogeneous nuclear ribonucleoprotein A129770.050-0.0593No
40RHOBTB2RHOBTB2
Entrez,  Source
Rho-related BTB domain containing 231700.048-0.0717No
41DNM1LDNM1L
Entrez,  Source
dynamin 1-like32350.047-0.0744No
42MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase32670.046-0.0745No
43IGFBP2IGFBP2
Entrez,  Source
insulin-like growth factor binding protein 2, 36kDa33030.046-0.0750No
44OTUD4OTUD4
Entrez,  Source
OTU domain containing 433070.046-0.0731No
45OAS1OAS1
Entrez,  Source
2',5'-oligoadenylate synthetase 1, 40/46kDa33130.046-0.0713No
46FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)33150.046-0.0692No
47CAND2CAND2
Entrez,  Source
cullin-associated and neddylation-dissociated 2 (putative)34100.044-0.0742No
48WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 134590.044-0.0758No
49CD164CD164
Entrez,  Source
CD164 molecule, sialomucin35160.043-0.0780No
50WT1WT1
Entrez,  Source
Wilms tumor 135190.043-0.0761No
51AIF1AIF1
Entrez,  Source
allograft inflammatory factor 136790.041-0.0863No
52CANXCANX
Entrez,  Source
calnexin37530.040-0.0900No
53ARHGAP5ARHGAP5
Entrez,  Source
Rho GTPase activating protein 538330.039-0.0942No
54CSDACSDA
Entrez,  Source
cold shock domain protein A38800.038-0.0958No
55HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)39150.038-0.0966No
56TCF21TCF21
Entrez,  Source
transcription factor 2139480.037-0.0973No
57CEBPDCEBPD
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), delta42230.034-0.1166No
58RARRES2RARRES2
Entrez,  Source
retinoic acid receptor responder (tazarotene induced) 242620.033-0.1179No
59SUB1SUB1
Entrez,  Source
SUB1 homolog (S. cerevisiae)42820.033-0.1178No
60ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1544010.031-0.1253No
61SYNPOSYNPO
Entrez,  Source
synaptopodin44860.030-0.1303No
62GJA1GJA1
Entrez,  Source
gap junction protein, alpha 1, 43kDa (connexin 43)47830.027-0.1516No
63PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 148330.026-0.1541No
64PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1450190.024-0.1671No
65CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)50200.024-0.1660No
66RAD23BRAD23B
Entrez,  Source
RAD23 homolog B (S. cerevisiae)50210.024-0.1649No
67PDIA3PDIA3
Entrez,  Source
protein disulfide isomerase family A, member 350840.023-0.1685No
68BMP7BMP7
Entrez,  Source
bone morphogenetic protein 7 (osteogenic protein 1)51070.023-0.1691No
69DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 151170.022-0.1687No
70SULF1SULF1
Entrez,  Source
sulfatase 151210.022-0.1679No
71GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha51780.022-0.1711No
72TNNT2TNNT2
Entrez,  Source
troponin T type 2 (cardiac)53340.020-0.1820No
73XPO1XPO1
Entrez,  Source
exportin 1 (CRM1 homolog, yeast)54060.019-0.1865No
74MECP2MECP2
Entrez,  Source
methyl CpG binding protein 2 (Rett syndrome)54440.019-0.1884No
75PSMA6PSMA6
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 654750.019-0.1898No
76ATXN1ATXN1
Entrez,  Source
ataxin 155520.018-0.1948No
77GAB2GAB2
Entrez,  Source
GRB2-associated binding protein 255970.017-0.1973No
78NTRK2NTRK2
Entrez,  Source
neurotrophic tyrosine kinase, receptor, type 256300.017-0.1990No
79GRIK2GRIK2
Entrez,  Source
glutamate receptor, ionotropic, kainate 257110.016-0.2043No
80PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)59900.013-0.2249No
81COLQCOLQ
Entrez,  Source
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase60220.013-0.2267No
82MTX2MTX2
Entrez,  Source
metaxin 260520.012-0.2283No
83NAB1NAB1
Entrez,  Source
NGFI-A binding protein 1 (EGR1 binding protein 1)62100.011-0.2398No
84EXOSC7EXOSC7
Entrez,  Source
exosome component 763600.009-0.2507No
85COL3A1COL3A1
Entrez,  Source
collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant)63890.009-0.2524No
86CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 164140.008-0.2538No
87ADD3ADD3
Entrez,  Source
adducin 3 (gamma)64720.008-0.2578No
88TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 364840.008-0.2583No
89ARL1ARL1
Entrez,  Source
ADP-ribosylation factor-like 167270.005-0.2765No
90VPS26AVPS26A
Entrez,  Source
vacuolar protein sorting 26 homolog A (yeast)67580.005-0.2786No
91PHYHIPPHYHIP
Entrez,  Source
phytanoyl-CoA 2-hydroxylase interacting protein68390.004-0.2845No
92ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 668990.003-0.2889No
93YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide69040.003-0.2890No
94NAPGNAPG
Entrez,  Source
N-ethylmaleimide-sensitive factor attachment protein, gamma69050.003-0.2889No
95HNRPCHNRPC
Entrez,  Source
heterogeneous nuclear ribonucleoprotein C (C1/C2)69180.003-0.2897No
96MAPK10MAPK10
Entrez,  Source
mitogen-activated protein kinase 1069620.002-0.2928No
97DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A69640.002-0.2928No
98TAX1BP1TAX1BP1
Entrez,  Source
Tax1 (human T-cell leukemia virus type I) binding protein 169830.002-0.2941No
99TGFBR3TGFBR3
Entrez,  Source
transforming growth factor, beta receptor III (betaglycan, 300kDa)69860.002-0.2941No
100ADORA1ADORA1
Entrez,  Source
adenosine A1 receptor71240.001-0.3046No
101TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)71490.000-0.3064No
102RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family7222-0.000-0.3118No
103PSMA2PSMA2
Entrez,  Source
proteasome (prosome, macropain) subunit, alpha type, 27318-0.002-0.3190No
104PTPN11PTPN11
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)7325-0.002-0.3194No
105SKP1ASKP1A
Entrez,  Source
S-phase kinase-associated protein 1A (p19A)7360-0.002-0.3219No
106HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like7633-0.005-0.3424No
107TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7655-0.005-0.3437No
108RHEBRHEB
Entrez,  Source
Ras homolog enriched in brain7658-0.005-0.3436No
109XRCC5XRCC5
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)7688-0.006-0.3456No
110PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)7920-0.009-0.3628No
111WARSWARS
Entrez,  Source
tryptophanyl-tRNA synthetase7995-0.009-0.3680No
112GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 18014-0.010-0.3689No
113PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa8159-0.011-0.3794No
114CFLARCFLAR
Entrez,  Source
CASP8 and FADD-like apoptosis regulator8465-0.015-0.4019No
115PRDX6PRDX6
Entrez,  Source
peroxiredoxin 68502-0.016-0.4039No
116UBE2L6UBE2L6
Entrez,  Source
ubiquitin-conjugating enzyme E2L 68567-0.016-0.4080No
117OPTNOPTN
Entrez,  Source
optineurin8689-0.018-0.4164No
118PLCG2PLCG2
Entrez,  Source
phospholipase C, gamma 2 (phosphatidylinositol-specific)8698-0.018-0.4162No
119HSP90AA1HSP90AA1
Entrez,  Source
heat shock protein 90kDa alpha (cytosolic), class A member 18764-0.019-0.4202No
120TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 58849-0.020-0.4257No
121LPLLPL
Entrez,  Source
lipoprotein lipase8894-0.020-0.4281No
122UGP2UGP2
Entrez,  Source
UDP-glucose pyrophosphorylase 28944-0.021-0.4308No
123PFN2PFN2
Entrez,  Source
profilin 28946-0.021-0.4299No
124BST2BST2
Entrez,  Source
bone marrow stromal cell antigen 29025-0.022-0.4347No
125TBCATBCA
Entrez,  Source
tubulin-specific chaperone a9038-0.022-0.4346No
126STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa9067-0.023-0.4356No
127RDXRDX
Entrez,  Source
radixin9216-0.025-0.4458No
128ST3GAL6ST3GAL6
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 69231-0.025-0.4456No
129STX7STX7
Entrez,  Source
syntaxin 79244-0.025-0.4454No
130DDNDDN
Entrez,  Source
dendrin9275-0.026-0.4464No
131DNAJA1DNAJA1
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily A, member 19406-0.028-0.4550No
132ACBD3ACBD3
Entrez,  Source
acyl-Coenzyme A binding domain containing 39411-0.028-0.4540No
133MYO1BMYO1B
Entrez,  Source
myosin IB9460-0.028-0.4563No
134HMGN1HMGN1
Entrez,  Source
high-mobility group nucleosome binding domain 19508-0.029-0.4585No
135AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)9650-0.031-0.4678No
136ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29652-0.031-0.4664No
137GLULGLUL
Entrez,  Source
glutamate-ammonia ligase (glutamine synthetase)9734-0.033-0.4710No
138PLXNB2PLXNB2
Entrez,  Source
plexin B29766-0.033-0.4718No
139NBNNBN
Entrez,  Source
nibrin9779-0.033-0.4711No
140CLIC5CLIC5
Entrez,  Source
chloride intracellular channel 59815-0.034-0.4722No
141BIRC2BIRC2
Entrez,  Source
baculoviral IAP repeat-containing 29946-0.036-0.4804No
142PCMT1PCMT1
Entrez,  Source
protein-L-isoaspartate (D-aspartate) O-methyltransferase10054-0.038-0.4868No
143HMGN3HMGN3
Entrez,  Source
high mobility group nucleosomal binding domain 310126-0.039-0.4903No
144FNBP1FNBP1
Entrez,  Source
formin binding protein 110158-0.039-0.4908No
145CACNB2CACNB2
Entrez,  Source
calcium channel, voltage-dependent, beta 2 subunit10205-0.040-0.4924No
146RAB21RAB21
Entrez,  Source
RAB21, member RAS oncogene family10253-0.041-0.4940No
147SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)10284-0.041-0.4944No
148ING1ING1
Entrez,  Source
inhibitor of growth family, member 110309-0.042-0.4942No
149YWHAZYWHAZ
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide10313-0.042-0.4924No
150SEPT2SEPT2
Entrez,  Source
septin 210339-0.042-0.4923No
151PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform10348-0.042-0.4909No
152ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 210401-0.044-0.4928No
153GTF2A2GTF2A2
Entrez,  Source
general transcription factor IIA, 2, 12kDa10421-0.044-0.4922No
154EXOC7EXOC7
Entrez,  Source
exocyst complex component 710572-0.046-0.5014No
155CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b10642-0.048-0.5044No
156LANCL1LANCL1
Entrez,  Source
LanC lantibiotic synthetase component C-like 1 (bacterial)10649-0.048-0.5025No
157ATXN10ATXN10
Entrez,  Source
ataxin 1010662-0.048-0.5012No
158KIF5BKIF5B
Entrez,  Source
kinesin family member 5B10742-0.050-0.5048No
159PARP1PARP1
Entrez,  Source
poly (ADP-ribose) polymerase family, member 110758-0.051-0.5035No
160SMARCA2SMARCA2
Entrez,  Source
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 210834-0.052-0.5067No
161COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 410867-0.053-0.5066No
162DDX17DDX17
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1710913-0.054-0.5075No
163EPS15EPS15
Entrez,  Source
epidermal growth factor receptor pathway substrate 1511024-0.056-0.5132No
164PAK1PAK1
Entrez,  Source
p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)11055-0.057-0.5127No
165NMINMI
Entrez,  Source
N-myc (and STAT) interactor11093-0.058-0.5128No
166TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)11148-0.059-0.5141No
167CSPG2CSPG2
Entrez,  Source
chondroitin sulfate proteoglycan 2 (versican)11206-0.060-0.5156No
168AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase11348-0.064-0.5233No
169PODXLPODXL
Entrez,  Source
podocalyxin-like11359-0.064-0.5210No
170CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 111368-0.064-0.5185No
171BCAMBCAM
Entrez,  Source
basal cell adhesion molecule (Lutheran blood group)11372-0.064-0.5157No
172NEDD9NEDD9
Entrez,  Source
neural precursor cell expressed, developmentally down-regulated 911537-0.070-0.5249No
173PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D11551-0.070-0.5225No
174ATP6AP2ATP6AP2
Entrez,  Source
ATPase, H+ transporting, lysosomal accessory protein 211566-0.071-0.5202No
175CASTCAST
Entrez,  Source
calpastatin11630-0.073-0.5215No
176TMEM23TMEM23
Entrez,  Source
transmembrane protein 2311708-0.076-0.5238No
177LITAFLITAF
Entrez,  Source
lipopolysaccharide-induced TNF factor11763-0.078-0.5242No
178DPYSL3DPYSL3
Entrez,  Source
dihydropyrimidinase-like 311772-0.078-0.5210No
179CAPN2CAPN2
Entrez,  Source
calpain 2, (m/II) large subunit11891-0.083-0.5261Yes
180CXADRCXADR
Entrez,  Source
coxsackie virus and adenovirus receptor11909-0.084-0.5234Yes
181NPHS1NPHS1
Entrez,  Source
nephrosis 1, congenital, Finnish type (nephrin)11929-0.084-0.5208Yes
182NPTNNPTN
Entrez,  Source
neuroplastin12006-0.087-0.5224Yes
183CALM2CALM2
Entrez,  Source
calmodulin 2 (phosphorylase kinase, delta)12036-0.089-0.5204Yes
184PAWRPAWR
Entrez,  Source
PRKC, apoptosis, WT1, regulator12073-0.090-0.5188Yes
185PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)12156-0.094-0.5206Yes
186TAPBPTAPBP
Entrez,  Source
TAP binding protein (tapasin)12170-0.095-0.5170Yes
187DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 112190-0.096-0.5139Yes
188PRKCIPRKCI
Entrez,  Source
protein kinase C, iota12255-0.100-0.5140Yes
189MSH2MSH2
Entrez,  Source
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)12287-0.103-0.5115Yes
190ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)12336-0.106-0.5100Yes
191ABI1ABI1
Entrez,  Source
abl-interactor 112376-0.109-0.5078Yes
192HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 112456-0.115-0.5084Yes
193NFASCNFASC
Entrez,  Source
neurofascin homolog (chicken)12512-0.118-0.5069Yes
194PTGER4PTGER4
Entrez,  Source
prostaglandin E receptor 4 (subtype EP4)12537-0.120-0.5030Yes
195PLCE1PLCE1
Entrez,  Source
phospholipase C, epsilon 112550-0.121-0.4981Yes
196CYR61CYR61
Entrez,  Source
cysteine-rich, angiogenic inducer, 6112557-0.122-0.4927Yes
197GYG1GYG1
Entrez,  Source
glycogenin 112593-0.125-0.4894Yes
198PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 112603-0.125-0.4841Yes
199GSTA4GSTA4
Entrez,  Source
glutathione S-transferase A412608-0.126-0.4784Yes
200BMP2BMP2
Entrez,  Source
bone morphogenetic protein 212648-0.130-0.4752Yes
201PSMB9PSMB9
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)12661-0.131-0.4699Yes
202DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)12710-0.136-0.4670Yes
203BIRC3BIRC3
Entrez,  Source
baculoviral IAP repeat-containing 312722-0.137-0.4613Yes
204MYO1EMYO1E
Entrez,  Source
myosin IE12727-0.138-0.4550Yes
205CALD1CALD1
Entrez,  Source
caldesmon 112735-0.139-0.4489Yes
206DAG1DAG1
Entrez,  Source
dystroglycan 1 (dystrophin-associated glycoprotein 1)12762-0.143-0.4440Yes
207RAI14RAI14
Entrez,  Source
retinoic acid induced 1412786-0.146-0.4388Yes
208ALDH3B1ALDH3B1
Entrez,  Source
aldehyde dehydrogenase 3 family, member B112850-0.156-0.4362Yes
209PLSCR1PLSCR1
Entrez,  Source
phospholipid scramblase 112879-0.161-0.4306Yes
210GRK5GRK5
Entrez,  Source
G protein-coupled receptor kinase 512883-0.162-0.4231Yes
211PDE4BPDE4B
Entrez,  Source
phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)12954-0.177-0.4200Yes
212CD47CD47
Entrez,  Source
CD47 molecule12956-0.177-0.4116Yes
213SCRN1SCRN1
Entrez,  Source
secernin 112993-0.186-0.4054Yes
214AGRINAGRIN
Entrez,  Source
agrin13039-0.202-0.3992Yes
215PRKAR2BPRKAR2B
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type II, beta13060-0.212-0.3906Yes
216RGS10RGS10
Entrez,  Source
regulator of G-protein signalling 1013069-0.218-0.3808Yes
217TMEM123TMEM123
Entrez,  Source
transmembrane protein 12313102-0.234-0.3721Yes
218UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase13105-0.234-0.3610Yes
219PDGFAPDGFA
Entrez,  Source
platelet-derived growth factor alpha polypeptide13145-0.254-0.3518Yes
220GPNMBGPNMB
Entrez,  Source
glycoprotein (transmembrane) nmb13168-0.269-0.3407Yes
221SERINC5SERINC5
Entrez,  Source
serine incorporator 513209-0.303-0.3292Yes
222PAMPAM
Entrez,  Source
peptidylglycine alpha-amidating monooxygenase13213-0.306-0.3149Yes
223TYRO3TYRO3
Entrez,  Source
TYRO3 protein tyrosine kinase13214-0.309-0.3001Yes
224SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 113215-0.309-0.2853Yes
225F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor13224-0.321-0.2706Yes
226CITED2CITED2
Entrez,  Source
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 213226-0.322-0.2553Yes
227PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513230-0.326-0.2400Yes
228NDRG1NDRG1
Entrez,  Source
N-myc downstream regulated gene 113242-0.345-0.2243Yes
229MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)13245-0.347-0.2079Yes
230CXCL2CXCL2
Entrez,  Source
chemokine (C-X-C motif) ligand 213254-0.355-0.1915Yes
231GPRC5AGPRC5A
Entrez,  Source
G protein-coupled receptor, family C, group 5, member A13268-0.382-0.1743Yes
232ADMADM
Entrez,  Source
adrenomedullin13274-0.393-0.1559Yes
233TSPAN3TSPAN3
Entrez,  Source
tetraspanin 313285-0.418-0.1367Yes
234MCM6MCM6
Entrez,  Source
MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)13301-0.469-0.1154Yes
235IGFBP7IGFBP7
Entrez,  Source
insulin-like growth factor binding protein 713304-0.474-0.0929Yes
236SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 113308-0.484-0.0699Yes
237ANXA1ANXA1
Entrez,  Source
annexin A113312-0.498-0.0463Yes
238CTGFCTGF
Entrez,  Source
connective tissue growth factor13313-0.503-0.0223Yes
239F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)13315-0.5110.0021Yes
Table: GSEA details [plain text format]



Fig 2: DIAB_NEPH_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: DIAB_NEPH_DN: Random ES distribution   
Gene set null distribution of ES for DIAB_NEPH_DN