Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | EGFPATHWAY |
| Enrichment Score (ES) | 0.5051086 |
| Normalized Enrichment Score (NES) | 1.5431851 |
| Nominal p-value | 0.03908046 |
| FDR q-value | 0.12415793 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 0 | 1.012 | 0.4613 | Yes |
| 2 | EGF | EGF Entrez, Source | epidermal growth factor (beta-urogastrone) | 316 | 0.148 | 0.5051 | Yes |
| 3 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 1674 | 0.075 | 0.4374 | No |
| 4 | RAF1 | RAF1 Entrez, Source | v-raf-1 murine leukemia viral oncogene homolog 1 | 2284 | 0.062 | 0.4202 | No |
| 5 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 2417 | 0.060 | 0.4376 | No |
| 6 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 2668 | 0.056 | 0.4443 | No |
| 7 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 2688 | 0.055 | 0.4682 | No |
| 8 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 4579 | 0.029 | 0.3395 | No |
| 9 | CSNK2A1 | CSNK2A1 Entrez, Source | casein kinase 2, alpha 1 polypeptide | 6997 | 0.002 | 0.1589 | No |
| 10 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 7179 | 0.000 | 0.1453 | No |
| 11 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 7310 | -0.002 | 0.1362 | No |
| 12 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 7619 | -0.005 | 0.1154 | No |
| 13 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | 0.0855 | No |
| 14 | MAP2K1 | MAP2K1 Entrez, Source | mitogen-activated protein kinase kinase 1 | 8219 | -0.012 | 0.0807 | No |
| 15 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 9067 | -0.023 | 0.0275 | No |
| 16 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 9267 | -0.025 | 0.0241 | No |
| 17 | STAT3 | STAT3 Entrez, Source | signal transducer and activator of transcription 3 (acute-phase response factor) | 9416 | -0.028 | 0.0257 | No |
| 18 | JAK1 | JAK1 Entrez, Source | Janus kinase 1 (a protein tyrosine kinase) | 10118 | -0.039 | -0.0093 | No |
| 19 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10315 | -0.042 | -0.0050 | No |
| 20 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 10643 | -0.048 | -0.0077 | No |
| 21 | PLCG1 | PLCG1 Entrez, Source | phospholipase C, gamma 1 | 11883 | -0.083 | -0.0631 | No |
| 22 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 12262 | -0.100 | -0.0457 | No |
| 23 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 12674 | -0.132 | -0.0165 | No |
| 24 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 12788 | -0.146 | 0.0416 | No |
