Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | EGF_HDMEC_UP |
| Enrichment Score (ES) | -0.6316688 |
| Normalized Enrichment Score (NES) | -1.8749543 |
| Nominal p-value | 0.0034722222 |
| FDR q-value | 0.026292857 |
| FWER p-Value | 0.762 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GNAS | GNAS Entrez, Source | GNAS complex locus | 1079 | 0.094 | -0.0540 | No |
| 2 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 1228 | 0.089 | -0.0397 | No |
| 3 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 1853 | 0.071 | -0.0662 | No |
| 4 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2163 | 0.065 | -0.0709 | No |
| 5 | TIE1 | TIE1 Entrez, Source | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 2639 | 0.056 | -0.0905 | No |
| 6 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 3303 | 0.046 | -0.1272 | No |
| 7 | RAD23B | RAD23B Entrez, Source | RAD23 homolog B (S. cerevisiae) | 5021 | 0.024 | -0.2494 | No |
| 8 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.2549 | No |
| 9 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.2950 | No |
| 10 | RPL6 | RPL6 Entrez, Source | ribosomal protein L6 | 6827 | 0.004 | -0.3731 | No |
| 11 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 7179 | 0.000 | -0.3995 | No |
| 12 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 7586 | -0.005 | -0.4287 | No |
| 13 | TCEB1 | TCEB1 Entrez, Source | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 7731 | -0.006 | -0.4377 | No |
| 14 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 8764 | -0.019 | -0.5098 | No |
| 15 | DAD1 | DAD1 Entrez, Source | defender against cell death 1 | 8855 | -0.020 | -0.5109 | No |
| 16 | GSTM1 | GSTM1 Entrez, Source | glutathione S-transferase M1 | 8992 | -0.022 | -0.5149 | No |
| 17 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 9329 | -0.026 | -0.5326 | No |
| 18 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 10196 | -0.040 | -0.5862 | No |
| 19 | ITGB1 | ITGB1 Entrez, Source | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 10521 | -0.046 | -0.5975 | No |
| 20 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 10584 | -0.047 | -0.5887 | No |
| 21 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 10674 | -0.049 | -0.5815 | No |
| 22 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 10706 | -0.050 | -0.5696 | No |
| 23 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11138 | -0.059 | -0.5851 | No |
| 24 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 11348 | -0.064 | -0.5825 | No |
| 25 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.6067 | Yes |
| 26 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 12221 | -0.098 | -0.5949 | Yes |
| 27 | TMSB10 | TMSB10 Entrez, Source | thymosin, beta 10 | 12400 | -0.111 | -0.5764 | Yes |
| 28 | PLAUR | PLAUR Entrez, Source | plasminogen activator, urokinase receptor | 12561 | -0.122 | -0.5534 | Yes |
| 29 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12716 | -0.137 | -0.5257 | Yes |
| 30 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13250 | -0.352 | -0.4648 | Yes |
| 31 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13254 | -0.355 | -0.3632 | Yes |
| 32 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13313 | -0.503 | -0.2233 | Yes |
| 33 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13335 | -0.786 | 0.0005 | Yes |
