Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | EICOSANOID_SYNTHESIS |
| Enrichment Score (ES) | 0.53751934 |
| Normalized Enrichment Score (NES) | 1.4469543 |
| Nominal p-value | 0.08791209 |
| FDR q-value | 0.17921783 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 583 | 0.119 | 0.1354 | Yes |
| 2 | ALOX15 | ALOX15 Entrez, Source | arachidonate 15-lipoxygenase | 851 | 0.105 | 0.2729 | Yes |
| 3 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 886 | 0.103 | 0.4256 | Yes |
| 4 | PTGES | PTGES Entrez, Source | prostaglandin E synthase | 1797 | 0.072 | 0.4658 | Yes |
| 5 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 2515 | 0.058 | 0.4994 | Yes |
| 6 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 3007 | 0.050 | 0.5375 | Yes |
| 7 | TBXAS1 | TBXAS1 Entrez, Source | thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) | 4744 | 0.027 | 0.4479 | No |
| 8 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 4818 | 0.026 | 0.4816 | No |
| 9 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 5243 | 0.021 | 0.4813 | No |
| 10 | GGT1 | GGT1 Entrez, Source | gamma-glutamyltransferase 1 | 5638 | 0.017 | 0.4768 | No |
| 11 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 5884 | 0.014 | 0.4796 | No |
| 12 | DPEP1 | DPEP1 Entrez, Source | dipeptidase 1 (renal) | 6607 | 0.006 | 0.4351 | No |
| 13 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 6985 | 0.002 | 0.4098 | No |
| 14 | LTC4S | LTC4S Entrez, Source | leukotriene C4 synthase | 7935 | -0.009 | 0.3517 | No |
| 15 | LTA4H | LTA4H Entrez, Source | leukotriene A4 hydrolase | 9958 | -0.036 | 0.2539 | No |
