Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | ELECTRON_CARRIER_ACTIVITY |
| Enrichment Score (ES) | 0.4055494 |
| Normalized Enrichment Score (NES) | 1.4698054 |
| Nominal p-value | 0.037220843 |
| FDR q-value | 0.16296995 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HAAO | HAAO Entrez, Source | 3-hydroxyanthranilate 3,4-dioxygenase | 143 | 0.195 | 0.0600 | Yes |
| 2 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 173 | 0.183 | 0.1243 | Yes |
| 3 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 566 | 0.121 | 0.1384 | Yes |
| 4 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 670 | 0.114 | 0.1718 | Yes |
| 5 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 712 | 0.111 | 0.2090 | Yes |
| 6 | GSR | GSR Entrez, Source | glutathione reductase | 1359 | 0.084 | 0.1907 | Yes |
| 7 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 1443 | 0.081 | 0.2139 | Yes |
| 8 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | 0.2390 | Yes |
| 9 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 1520 | 0.079 | 0.2656 | Yes |
| 10 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1562 | 0.078 | 0.2908 | Yes |
| 11 | DMGDH | DMGDH Entrez, Source | dimethylglycine dehydrogenase | 1702 | 0.074 | 0.3072 | Yes |
| 12 | NCF1 | NCF1 Entrez, Source | neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) | 1813 | 0.072 | 0.3249 | Yes |
| 13 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 1904 | 0.070 | 0.3435 | Yes |
| 14 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 1967 | 0.069 | 0.3638 | Yes |
| 15 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 2016 | 0.068 | 0.3847 | Yes |
| 16 | ETFDH | ETFDH Entrez, Source | electron-transferring-flavoprotein dehydrogenase | 2061 | 0.067 | 0.4055 | Yes |
| 17 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 2561 | 0.058 | 0.3888 | No |
| 18 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 2896 | 0.052 | 0.3825 | No |
| 19 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 3342 | 0.045 | 0.3653 | No |
| 20 | MTRR | MTRR Entrez, Source | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 3727 | 0.040 | 0.3510 | No |
| 21 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 3939 | 0.037 | 0.3486 | No |
| 22 | NQO2 | NQO2 Entrez, Source | NAD(P)H dehydrogenase, quinone 2 | 4039 | 0.036 | 0.3541 | No |
| 23 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 4134 | 0.035 | 0.3596 | No |
| 24 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 4149 | 0.034 | 0.3710 | No |
| 25 | HMOX2 | HMOX2 Entrez, Source | heme oxygenase (decycling) 2 | 4560 | 0.029 | 0.3508 | No |
| 26 | NDUFS7 | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 4676 | 0.028 | 0.3522 | No |
| 27 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 4751 | 0.027 | 0.3564 | No |
| 28 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 4827 | 0.026 | 0.3601 | No |
| 29 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 5418 | 0.019 | 0.3226 | No |
| 30 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 5421 | 0.019 | 0.3294 | No |
| 31 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 5876 | 0.014 | 0.3004 | No |
| 32 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 6092 | 0.012 | 0.2885 | No |
| 33 | COX5A | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 6151 | 0.011 | 0.2883 | No |
| 34 | ETFA | ETFA Entrez, Source | electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) | 6187 | 0.011 | 0.2897 | No |
| 35 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 6270 | 0.010 | 0.2872 | No |
| 36 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 6869 | 0.003 | 0.2434 | No |
| 37 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 6937 | 0.003 | 0.2393 | No |
| 38 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 6946 | 0.003 | 0.2396 | No |
| 39 | NDUFS2 | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 7120 | 0.001 | 0.2269 | No |
| 40 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 7556 | -0.004 | 0.1957 | No |
| 41 | TXNRD2 | TXNRD2 Entrez, Source | thioredoxin reductase 2 | 8441 | -0.015 | 0.1346 | No |
| 42 | CYB5R2 | CYB5R2 Entrez, Source | cytochrome b5 reductase 2 | 8613 | -0.017 | 0.1279 | No |
| 43 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 8630 | -0.017 | 0.1330 | No |
| 44 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 8794 | -0.019 | 0.1277 | No |
| 45 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 8945 | -0.021 | 0.1241 | No |
| 46 | NDUFS4 | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 9118 | -0.023 | 0.1196 | No |
| 47 | CYB5R3 | CYB5R3 Entrez, Source | cytochrome b5 reductase 3 | 10221 | -0.040 | 0.0512 | No |
| 48 | CYB5R4 | CYB5R4 Entrez, Source | cytochrome b5 reductase 4 | 11499 | -0.068 | -0.0201 | No |
| 49 | DEGS1 | DEGS1 Entrez, Source | degenerative spermatocyte homolog 1, lipid desaturase (Drosophila) | 11526 | -0.069 | 0.0030 | No |
| 50 | FDX1 | FDX1 Entrez, Source | ferredoxin 1 | 11956 | -0.085 | 0.0016 | No |
| 51 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 12386 | -0.110 | 0.0091 | No |
| 52 | CYBA | CYBA Entrez, Source | cytochrome b-245, alpha polypeptide | 12938 | -0.173 | 0.0304 | No |
