Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | ELECTRON_TRANSPORTER_ACTIVITY |
| Enrichment Score (ES) | 0.4660757 |
| Normalized Enrichment Score (NES) | 1.7781022 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.036961775 |
| FWER p-Value | 0.944 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 19 | 0.354 | 0.0761 | Yes |
| 2 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 54 | 0.279 | 0.1346 | Yes |
| 3 | HAAO | HAAO Entrez, Source | 3-hydroxyanthranilate 3,4-dioxygenase | 143 | 0.195 | 0.1708 | Yes |
| 4 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 173 | 0.183 | 0.2088 | Yes |
| 5 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 247 | 0.160 | 0.2383 | Yes |
| 6 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 506 | 0.124 | 0.2462 | Yes |
| 7 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 566 | 0.121 | 0.2681 | Yes |
| 8 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 670 | 0.114 | 0.2852 | Yes |
| 9 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 712 | 0.111 | 0.3065 | Yes |
| 10 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 1081 | 0.094 | 0.2994 | Yes |
| 11 | SRD5A2 | SRD5A2 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) | 1342 | 0.085 | 0.2983 | Yes |
| 12 | GSR | GSR Entrez, Source | glutathione reductase | 1359 | 0.084 | 0.3155 | Yes |
| 13 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 1443 | 0.081 | 0.3270 | Yes |
| 14 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1493 | 0.080 | 0.3407 | Yes |
| 15 | ETFB | ETFB Entrez, Source | electron-transfer-flavoprotein, beta polypeptide | 1520 | 0.079 | 0.3561 | Yes |
| 16 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 1556 | 0.078 | 0.3705 | Yes |
| 17 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1562 | 0.078 | 0.3872 | Yes |
| 18 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.3970 | Yes |
| 19 | DHRS4 | DHRS4 Entrez, Source | dehydrogenase/reductase (SDR family) member 4 | 1791 | 0.072 | 0.4026 | Yes |
| 20 | NCF1 | NCF1 Entrez, Source | neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) | 1813 | 0.072 | 0.4167 | Yes |
| 21 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 1904 | 0.070 | 0.4252 | Yes |
| 22 | QDPR | QDPR Entrez, Source | quinoid dihydropteridine reductase | 1967 | 0.069 | 0.4357 | Yes |
| 23 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 1987 | 0.068 | 0.4492 | Yes |
| 24 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 2098 | 0.066 | 0.4554 | Yes |
| 25 | MB | MB Entrez, Source | myoglobin | 2146 | 0.065 | 0.4661 | Yes |
| 26 | LOXL1 | LOXL1 Entrez, Source | lysyl oxidase-like 1 | 2447 | 0.060 | 0.4565 | No |
| 27 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 2896 | 0.052 | 0.4341 | No |
| 28 | MTRR | MTRR Entrez, Source | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 3727 | 0.040 | 0.3804 | No |
| 29 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 3915 | 0.038 | 0.3746 | No |
| 30 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 3939 | 0.037 | 0.3810 | No |
| 31 | NQO2 | NQO2 Entrez, Source | NAD(P)H dehydrogenase, quinone 2 | 4039 | 0.036 | 0.3814 | No |
| 32 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 4114 | 0.035 | 0.3834 | No |
| 33 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 4134 | 0.035 | 0.3896 | No |
| 34 | TXN2 | TXN2 Entrez, Source | thioredoxin 2 | 4139 | 0.035 | 0.3969 | No |
| 35 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 4559 | 0.029 | 0.3717 | No |
| 36 | HMOX2 | HMOX2 Entrez, Source | heme oxygenase (decycling) 2 | 4560 | 0.029 | 0.3781 | No |
| 37 | P4HB | P4HB Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | 4586 | 0.029 | 0.3826 | No |
| 38 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 4751 | 0.027 | 0.3761 | No |
| 39 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 4758 | 0.027 | 0.3815 | No |
| 40 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 4827 | 0.026 | 0.3821 | No |
| 41 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 5418 | 0.019 | 0.3418 | No |
| 42 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 5484 | 0.019 | 0.3410 | No |
| 43 | GPX4 | GPX4 Entrez, Source | glutathione peroxidase 4 (phospholipid hydroperoxidase) | 5917 | 0.014 | 0.3114 | No |
| 44 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 6092 | 0.012 | 0.3010 | No |
| 45 | COX5A | COX5A Entrez, Source | cytochrome c oxidase subunit Va | 6151 | 0.011 | 0.2991 | No |
| 46 | PRDX5 | PRDX5 Entrez, Source | peroxiredoxin 5 | 6258 | 0.010 | 0.2933 | No |
| 47 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 6869 | 0.003 | 0.2482 | No |
| 48 | CYCS | CYCS Entrez, Source | cytochrome c, somatic | 6937 | 0.003 | 0.2437 | No |
| 49 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 6946 | 0.003 | 0.2436 | No |
| 50 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 7461 | -0.003 | 0.2056 | No |
| 51 | BLVRA | BLVRA Entrez, Source | biliverdin reductase A | 7498 | -0.004 | 0.2037 | No |
| 52 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 7556 | -0.004 | 0.2004 | No |
| 53 | TXNL2 | TXNL2 Entrez, Source | thioredoxin-like 2 | 8255 | -0.012 | 0.1505 | No |
| 54 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 8630 | -0.017 | 0.1262 | No |
| 55 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 8794 | -0.019 | 0.1181 | No |
| 56 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 8945 | -0.021 | 0.1114 | No |
| 57 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 9309 | -0.026 | 0.0898 | No |
| 58 | PRDX2 | PRDX2 Entrez, Source | peroxiredoxin 2 | 9329 | -0.026 | 0.0941 | No |
| 59 | HNRPM | HNRPM Entrez, Source | heterogeneous nuclear ribonucleoprotein M | 10311 | -0.042 | 0.0294 | No |
| 60 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 10547 | -0.046 | 0.0218 | No |
| 61 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 10749 | -0.051 | 0.0177 | No |
| 62 | COX15 | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 10952 | -0.055 | 0.0145 | No |
| 63 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 12235 | -0.099 | -0.0604 | No |
| 64 | SRD5A1 | SRD5A1 Entrez, Source | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 12386 | -0.110 | -0.0477 | No |
| 65 | GPX3 | GPX3 Entrez, Source | glutathione peroxidase 3 (plasma) | 13121 | -0.240 | -0.0504 | No |
| 66 | PAM | PAM Entrez, Source | peptidylglycine alpha-amidating monooxygenase | 13213 | -0.306 | 0.0097 | No |
