Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classdouble_gel_48h
GeneSetENDOPLASMIC_RETICULUM
Enrichment Score (ES)0.3231985
Normalized Enrichment Score (NES)1.4314599
Nominal p-value0.003215434
FDR q-value0.18969141
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: ENDOPLASMIC_RETICULUM   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1SLC27A5SLC27A5
Entrez,  Source
solute carrier family 27 (fatty acid transporter), member 5120.3950.0388Yes
2TM7SF2TM7SF2
Entrez,  Source
transmembrane 7 superfamily member 2240.3400.0721Yes
3EBPEBP
Entrez,  Source
emopamil binding protein (sterol isomerase)450.2900.0998Yes
4HMGCRHMGCR
Entrez,  Source
3-hydroxy-3-methylglutaryl-Coenzyme A reductase550.2780.1270Yes
5AADACAADAC
Entrez,  Source
arylacetamide deacetylase (esterase)590.2690.1538Yes
6HYOU1HYOU1
Entrez,  Source
hypoxia up-regulated 1680.2550.1788Yes
7SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like900.2360.2010Yes
8PDIA4PDIA4
Entrez,  Source
protein disulfide isomerase family A, member 41510.1920.2157Yes
9DHCR24DHCR24
Entrez,  Source
24-dehydrocholesterol reductase1670.1850.2331Yes
10RTN1RTN1
Entrez,  Source
reticulon 11810.1780.2501Yes
11DHCR7DHCR7
Entrez,  Source
7-dehydrocholesterol reductase2470.1600.2612Yes
12OPRM1OPRM1
Entrez,  Source
opioid receptor, mu 14810.1270.2563Yes
13PEX16PEX16
Entrez,  Source
peroxisomal biogenesis factor 164960.1250.2678Yes
14CLDN14CLDN14
Entrez,  Source
claudin 145990.1180.2719Yes
15LMAN1LMAN1
Entrez,  Source
lectin, mannose-binding, 16070.1170.2832Yes
16CYP19A1CYP19A1
Entrez,  Source
cytochrome P450, family 19, subfamily A, polypeptide 16700.1140.2899Yes
17HERPUD1HERPUD1
Entrez,  Source
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 17160.1110.2977Yes
18THY1THY1
Entrez,  Source
Thy-1 cell surface antigen7480.1090.3063Yes
19CALRCALR
Entrez,  Source
calreticulin7680.1080.3157Yes
20CD320CD320
Entrez,  Source
CD320 molecule9010.1020.3160Yes
21SERP1SERP1
Entrez,  Source
-10840.0940.3116Yes
22SSR1SSR1
Entrez,  Source
signal sequence receptor, alpha (translocon-associated protein alpha)11330.0920.3172Yes
23ARSGARSG
Entrez,  Source
arylsulfatase G11750.0900.3232Yes
24UGCGL1UGCGL1
Entrez,  Source
UDP-glucose ceramide glucosyltransferase-like 113350.0850.3197No
25PTNPTN
Entrez,  Source
pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1)14390.0810.3200No
26CLDN8CLDN8
Entrez,  Source
claudin 817240.0740.3059No
27DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 917490.0730.3114No
28NSDHLNSDHL
Entrez,  Source
NAD(P) dependent steroid dehydrogenase-like17680.0730.3174No
29SLC33A1SLC33A1
Entrez,  Source
solute carrier family 33 (acetyl-CoA transporter), member 119180.0700.3131No
30PORPOR
Entrez,  Source
P450 (cytochrome) oxidoreductase25610.0580.2702No
31DNAJB11DNAJB11
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 1126270.0560.2709No
32HSD3B1HSD3B1
Entrez,  Source
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 126460.0560.2752No
33HMOX1HMOX1
Entrez,  Source
heme oxygenase (decycling) 127300.0550.2744No
34RTN4RRTN4R
Entrez,  Source
reticulon 4 receptor31090.0490.2506No
35GCS1GCS1
Entrez,  Source
-31750.0480.2505No
36DNM1LDNM1L
Entrez,  Source
dynamin 1-like32350.0470.2507No
37DHRS9DHRS9
Entrez,  Source
dehydrogenase/reductase (SDR family) member 932880.0460.2514No
38RPN1RPN1
Entrez,  Source
ribophorin I33010.0460.2551No
39ITPR2ITPR2
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 234680.0430.2469No
40GBA2GBA2
Entrez,  Source
glucosidase, beta (bile acid) 236300.0410.2388No
41SRPRSRPR
Entrez,  Source
signal recognition particle receptor ('docking protein')37130.0400.2366No
42CANXCANX
Entrez,  Source
calnexin37530.0400.2377No
43APEX1APEX1
Entrez,  Source
APEX nuclease (multifunctional DNA repair enzyme) 140280.0360.2205No
44KDELR2KDELR2
Entrez,  Source
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 240410.0360.2232No
45SREBF1SREBF1
Entrez,  Source
sterol regulatory element binding transcription factor 141090.0350.2217No
46PDIA5PDIA5
Entrez,  Source
protein disulfide isomerase family A, member 541240.0350.2241No
47GPC2GPC2
Entrez,  Source
glypican 2 (cerebroglycan)44520.0310.2024No
48S100A1S100A1
Entrez,  Source
S100 calcium binding protein A144590.0300.2050No
49P4HBP4HB
Entrez,  Source
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide45860.0290.1983No
50PDIA6PDIA6
Entrez,  Source
protein disulfide isomerase family A, member 646240.0280.1984No
51ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)46400.0280.2001No
52ACO1ACO1
Entrez,  Source
aconitase 1, soluble46550.0280.2018No
53PDIA3PDIA3
Entrez,  Source
protein disulfide isomerase family A, member 350840.0230.1717No
54BNIP1BNIP1
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 151500.0220.1689No
55VWFVWF
Entrez,  Source
von Willebrand factor52960.0200.1600No
56RPN2RPN2
Entrez,  Source
ribophorin II56860.0160.1321No
57PLA2G2APLA2G2A
Entrez,  Source
phospholipase A2, group IIA (platelets, synovial fluid)58840.0140.1186No
58SEMA4FSEMA4F
Entrez,  Source
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F59180.0140.1175No
59PIGVPIGV
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class V59390.0130.1173No
60ADFPADFP
Entrez,  Source
adipose differentiation-related protein59420.0130.1185No
61NCSTNNCSTN
Entrez,  Source
nicastrin61040.0120.1075No
62CLN3CLN3
Entrez,  Source
ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)61390.0120.1061No
63TRPC4APTRPC4AP
Entrez,  Source
transient receptor potential cation channel, subfamily C, member 4 associated protein62530.0100.0985No
64STX18STX18
Entrez,  Source
syntaxin 1862780.0100.0977No
65TEGTTEGT
Entrez,  Source
testis enhanced gene transcript (BAX inhibitor 1)62840.0100.0983No
66CES2CES2
Entrez,  Source
carboxylesterase 2 (intestine, liver)65010.0080.0827No
67SV2ASV2A
Entrez,  Source
synaptic vesicle glycoprotein 2A65130.0070.0826No
68PPIBPPIB
Entrez,  Source
peptidylprolyl isomerase B (cyclophilin B)65160.0070.0832No
69BSCL2BSCL2
Entrez,  Source
Bernardinelli-Seip congenital lipodystrophy 2 (seipin)66460.0060.0740No
70MALMAL
Entrez,  Source
mal, T-cell differentiation protein67790.0040.0645No
71SYVN1SYVN1
Entrez,  Source
synovial apoptosis inhibitor 1, synoviolin68050.0040.0630No
72PTGDSPTGDS
Entrez,  Source
prostaglandin D2 synthase 21kDa (brain)69850.0020.0496No
73RETSATRETSAT
Entrez,  Source
retinol saturase (all-trans-retinol 13,14-reductase)70900.0010.0418No
74RYR1RYR1
Entrez,  Source
ryanodine receptor 1 (skeletal)71580.0000.0368No
75PSENENPSENEN
Entrez,  Source
presenilin enhancer 2 homolog (C. elegans)71620.0000.0366No
76RPL10RPL10
Entrez,  Source
ribosomal protein L107202-0.0000.0337No
77NPLOC4NPLOC4
Entrez,  Source
nuclear protein localization 4 homolog (S. cerevisiae)7204-0.0000.0336No
78ERO1LERO1L
Entrez,  Source
ERO1-like (S. cerevisiae)7209-0.0000.0333No
79GNAZGNAZ
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha z polypeptide7248-0.0010.0305No
80ATP1A3ATP1A3
Entrez,  Source
ATPase, Na+/K+ transporting, alpha 3 polypeptide7330-0.0020.0246No
81ZW10ZW10
Entrez,  Source
ZW10, kinetochore associated, homolog (Drosophila)7453-0.0030.0156No
82APOC1APOC1
Entrez,  Source
apolipoprotein C-I7456-0.0030.0158No
83ALDH3A1ALDH3A1
Entrez,  Source
aldehyde dehydrogenase 3 family, memberA17461-0.0030.0158No
84TPST2TPST2
Entrez,  Source
tyrosylprotein sulfotransferase 27610-0.0050.0051No
85SLC36A1SLC36A1
Entrez,  Source
solute carrier family 36 (proton/amino acid symporter), member 17653-0.0050.0025No
86APOA5APOA5
Entrez,  Source
apolipoprotein A-V7763-0.007-0.0051No
87ICMTICMT
Entrez,  Source
isoprenylcysteine carboxyl methyltransferase7827-0.007-0.0092No
88VCPVCP
Entrez,  Source
valosin-containing protein7832-0.007-0.0087No
89AGPAT1AGPAT1
Entrez,  Source
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)7919-0.009-0.0144No
90PDZD2PDZD2
Entrez,  Source
PDZ domain containing 28263-0.013-0.0391No
91CTSZCTSZ
Entrez,  Source
cathepsin Z8280-0.013-0.0391No
92PIGKPIGK
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class K8287-0.013-0.0382No
93MBTPS1MBTPS1
Entrez,  Source
membrane-bound transcription factor peptidase, site 18426-0.015-0.0472No
94SERINC1SERINC1
Entrez,  Source
serine incorporator 18655-0.018-0.0628No
95ALG3ALG3
Entrez,  Source
asparagine-linked glycosylation 3 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase)8704-0.018-0.0646No
96DAD1DAD1
Entrez,  Source
defender against cell death 18855-0.020-0.0740No
97MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 18960-0.021-0.0797No
98DULLARDDULLARD
Entrez,  Source
dullard homolog (Xenopus laevis)9054-0.023-0.0845No
99TOR1ATOR1A
Entrez,  Source
torsin family 1, member A (torsin A)9104-0.023-0.0859No
100NRP1NRP1
Entrez,  Source
neuropilin 19147-0.024-0.0867No
101PLOD3PLOD3
Entrez,  Source
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 39156-0.024-0.0849No
102STAU1STAU1
Entrez,  Source
staufen, RNA binding protein, homolog 1 (Drosophila)9189-0.024-0.0849No
103CLN8CLN8
Entrez,  Source
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)9201-0.024-0.0832No
104TXNDC4TXNDC4
Entrez,  Source
thioredoxin domain containing 4 (endoplasmic reticulum)9203-0.024-0.0809No
105TAS2R16TAS2R16
Entrez,  Source
taste receptor, type 2, member 169240-0.025-0.0811No
106POMT1POMT1
Entrez,  Source
protein-O-mannosyltransferase 19373-0.027-0.0884No
107SEP15SEP15
Entrez,  Source
-9382-0.027-0.0862No
108RAB14RAB14
Entrez,  Source
RAB14, member RAS oncogene family9475-0.029-0.0904No
109YIPF4YIPF4
Entrez,  Source
Yip1 domain family, member 49529-0.029-0.0914No
110STSSTS
Entrez,  Source
steroid sulfatase (microsomal), arylsulfatase C, isozyme S9956-0.036-0.1201No
111TMEM50BTMEM50B
Entrez,  Source
transmembrane protein 50B9970-0.036-0.1175No
112AVPR2AVPR2
Entrez,  Source
arginine vasopressin receptor 2 (nephrogenic diabetes insipidus)9972-0.036-0.1139No
113BDKRB1BDKRB1
Entrez,  Source
bradykinin receptor B110044-0.037-0.1155No
114YKT6YKT6
Entrez,  Source
YKT6 v-SNARE homolog (S. cerevisiae)10045-0.038-0.1118No
115PCMT1PCMT1
Entrez,  Source
protein-L-isoaspartate (D-aspartate) O-methyltransferase10054-0.038-0.1086No
116PIGCPIGC
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class C10066-0.038-0.1056No
117SEC22ASEC22A
Entrez,  Source
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)10135-0.039-0.1069No
118DPM2DPM2
Entrez,  Source
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit10215-0.040-0.1088No
119BAXBAX
Entrez,  Source
BCL2-associated X protein10281-0.041-0.1096No
120AKAP6AKAP6
Entrez,  Source
A kinase (PRKA) anchor protein 610317-0.042-0.1081No
121ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 310318-0.042-0.1039No
122TRAM1TRAM1
Entrez,  Source
translocation associated membrane protein 110392-0.043-0.1051No
123VAPBVAPB
Entrez,  Source
VAMP (vesicle-associated membrane protein)-associated protein B and C10452-0.044-0.1051No
124ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)10521-0.046-0.1057No
125PSEN1PSEN1
Entrez,  Source
presenilin 1 (Alzheimer disease 3)10571-0.046-0.1047No
126PIGSPIGS
Entrez,  Source
phosphatidylinositol glycan anchor biosynthesis, class S10690-0.049-0.1087No
127CIB1CIB1
Entrez,  Source
calcium and integrin binding 1 (calmyrin)10883-0.053-0.1180No
128ANP32AANP32A
Entrez,  Source
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A10934-0.054-0.1163No
129TXNDC1TXNDC1
Entrez,  Source
thioredoxin domain containing 111099-0.058-0.1229No
130STX8STX8
Entrez,  Source
syntaxin 811276-0.062-0.1300No
131FKBP9FKBP9
Entrez,  Source
FK506 binding protein 9, 63 kDa11407-0.065-0.1333No
132EIF2AK3EIF2AK3
Entrez,  Source
eukaryotic translation initiation factor 2-alpha kinase 311434-0.066-0.1287No
133CASP7CASP7
Entrez,  Source
caspase 7, apoptosis-related cysteine peptidase11446-0.066-0.1228No
134DEGS1DEGS1
Entrez,  Source
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)11526-0.069-0.1219No
135TMEM98TMEM98
Entrez,  Source
transmembrane protein 9811558-0.070-0.1171No
136KCNG3KCNG3
Entrez,  Source
potassium voltage-gated channel, subfamily G, member 311675-0.075-0.1184No
137PSEN2PSEN2
Entrez,  Source
presenilin 2 (Alzheimer disease 4)11726-0.076-0.1146No
138APH1AAPH1A
Entrez,  Source
anterior pharynx defective 1 homolog A (C. elegans)11754-0.077-0.1089No
139TAP2TAP2
Entrez,  Source
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)11767-0.078-0.1020No
140ERP29ERP29
Entrez,  Source
endoplasmic reticulum protein 2911877-0.082-0.1020No
141TLOC1TLOC1
Entrez,  Source
translocation protein 112024-0.088-0.1041No
142AGPAT6AGPAT6
Entrez,  Source
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)12037-0.089-0.0961No
143DHRS1DHRS1
Entrez,  Source
dehydrogenase/reductase (SDR family) member 112095-0.091-0.0913No
144CAMLGCAMLG
Entrez,  Source
calcium modulating ligand12165-0.095-0.0870No
145TAPBPTAPBP
Entrez,  Source
TAP binding protein (tapasin)12170-0.095-0.0777No
146HTRA2HTRA2
Entrez,  Source
HtrA serine peptidase 212173-0.095-0.0683No
147ABI1ABI1
Entrez,  Source
abl-interactor 112376-0.109-0.0727No
148HSD17B2HSD17B2
Entrez,  Source
hydroxysteroid (17-beta) dehydrogenase 212678-0.132-0.0822No
149SOAT1SOAT1
Entrez,  Source
sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 112692-0.134-0.0697No
150EHD4EHD4
Entrez,  Source
EH-domain containing 412744-0.140-0.0595No
151P4HA1P4HA1
Entrez,  Source
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I12791-0.146-0.0483No
152BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like12870-0.160-0.0382No
153PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)13090-0.227-0.0320No
154RCN2RCN2
Entrez,  Source
reticulocalbin 2, EF-hand calcium binding domain13116-0.238-0.0099No
155RTN4RTN4
Entrez,  Source
reticulon 413167-0.2690.0133No
Table: GSEA details [plain text format]



Fig 2: ENDOPLASMIC_RETICULUM   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: ENDOPLASMIC_RETICULUM: Random ES distribution   
Gene set null distribution of ES for ENDOPLASMIC_RETICULUM