Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | ET743_HELA_UP |
| Enrichment Score (ES) | -0.6284326 |
| Normalized Enrichment Score (NES) | -2.0148325 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0066017555 |
| FWER p-Value | 0.177 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 79 | 0.243 | 0.0446 | No |
| 2 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 329 | 0.145 | 0.0560 | No |
| 3 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 670 | 0.114 | 0.0541 | No |
| 4 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 1127 | 0.092 | 0.0390 | No |
| 5 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 1572 | 0.078 | 0.0218 | No |
| 6 | CASP4 | CASP4 Entrez, Source | caspase 4, apoptosis-related cysteine peptidase | 1853 | 0.071 | 0.0155 | No |
| 7 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 2506 | 0.058 | -0.0214 | No |
| 8 | FOLR1 | FOLR1 Entrez, Source | folate receptor 1 (adult) | 2708 | 0.055 | -0.0251 | No |
| 9 | PRG1 | PRG1 Entrez, Source | proteoglycan 1, secretory granule | 3518 | 0.043 | -0.0770 | No |
| 10 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 4827 | 0.026 | -0.1699 | No |
| 11 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.1917 | No |
| 12 | CASP9 | CASP9 Entrez, Source | caspase 9, apoptosis-related cysteine peptidase | 5394 | 0.019 | -0.2039 | No |
| 13 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 5663 | 0.016 | -0.2206 | No |
| 14 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.2279 | No |
| 15 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5929 | 0.014 | -0.2345 | No |
| 16 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 6282 | 0.010 | -0.2589 | No |
| 17 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 6360 | 0.009 | -0.2628 | No |
| 18 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.2999 | No |
| 19 | ASNS | ASNS Entrez, Source | asparagine synthetase | 7614 | -0.005 | -0.3552 | No |
| 20 | NUCB2 | NUCB2 Entrez, Source | nucleobindin 2 | 7742 | -0.006 | -0.3634 | No |
| 21 | ARL6IP1 | ARL6IP1 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 1 | 7958 | -0.009 | -0.3777 | No |
| 22 | DUSP5 | DUSP5 Entrez, Source | dual specificity phosphatase 5 | 8419 | -0.014 | -0.4093 | No |
| 23 | CLIC4 | CLIC4 Entrez, Source | chloride intracellular channel 4 | 9801 | -0.033 | -0.5062 | No |
| 24 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 10564 | -0.046 | -0.5538 | No |
| 25 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 10845 | -0.053 | -0.5640 | No |
| 26 | TGFBI | TGFBI Entrez, Source | transforming growth factor, beta-induced, 68kDa | 10868 | -0.053 | -0.5546 | No |
| 27 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 10944 | -0.055 | -0.5489 | No |
| 28 | AES | AES Entrez, Source | amino-terminal enhancer of split | 11117 | -0.058 | -0.5497 | No |
| 29 | CLU | CLU Entrez, Source | clusterin | 11686 | -0.075 | -0.5768 | No |
| 30 | CLDN7 | CLDN7 Entrez, Source | claudin 7 | 12374 | -0.109 | -0.6057 | Yes |
| 31 | ANXA4 | ANXA4 Entrez, Source | annexin A4 | 12446 | -0.114 | -0.5874 | Yes |
| 32 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12486 | -0.117 | -0.5661 | Yes |
| 33 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 12608 | -0.126 | -0.5490 | Yes |
| 34 | CSRP2 | CSRP2 Entrez, Source | cysteine and glycine-rich protein 2 | 12792 | -0.147 | -0.5322 | Yes |
| 35 | EML2 | EML2 Entrez, Source | echinoderm microtubule associated protein like 2 | 12859 | -0.158 | -0.5044 | Yes |
| 36 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 12977 | -0.184 | -0.4750 | Yes |
| 37 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 13105 | -0.234 | -0.4359 | Yes |
| 38 | GPNMB | GPNMB Entrez, Source | glycoprotein (transmembrane) nmb | 13168 | -0.269 | -0.3845 | Yes |
| 39 | CPE | CPE Entrez, Source | carboxypeptidase E | 13284 | -0.413 | -0.3072 | Yes |
| 40 | IGFBP7 | IGFBP7 Entrez, Source | insulin-like growth factor binding protein 7 | 13304 | -0.474 | -0.2101 | Yes |
| 41 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13312 | -0.498 | -0.1070 | Yes |
| 42 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13320 | -0.525 | 0.0017 | Yes |
