Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | EXCITATORY_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY |
| Enrichment Score (ES) | 0.5109265 |
| Normalized Enrichment Score (NES) | 1.4931456 |
| Nominal p-value | 0.040632054 |
| FDR q-value | 0.15113714 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HTR3B | HTR3B Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 3B | 774 | 0.108 | 0.0765 | Yes |
| 2 | GLRB | GLRB Entrez, Source | glycine receptor, beta | 1617 | 0.077 | 0.1091 | Yes |
| 3 | CHRNA2 | CHRNA2 Entrez, Source | cholinergic receptor, nicotinic, alpha 2 (neuronal) | 1828 | 0.071 | 0.1827 | Yes |
| 4 | CHRNA1 | CHRNA1 Entrez, Source | cholinergic receptor, nicotinic, alpha 1 (muscle) | 2179 | 0.064 | 0.2366 | Yes |
| 5 | GLRA1 | GLRA1 Entrez, Source | glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome) | 2320 | 0.062 | 0.3031 | Yes |
| 6 | P2RX7 | P2RX7 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 7 | 2611 | 0.057 | 0.3521 | Yes |
| 7 | GLRA2 | GLRA2 Entrez, Source | glycine receptor, alpha 2 | 3025 | 0.050 | 0.3832 | Yes |
| 8 | CHRND | CHRND Entrez, Source | cholinergic receptor, nicotinic, delta | 3127 | 0.048 | 0.4359 | Yes |
| 9 | HTR3A | HTR3A Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 3A | 3637 | 0.041 | 0.4493 | Yes |
| 10 | CHRNA3 | CHRNA3 Entrez, Source | cholinergic receptor, nicotinic, alpha 3 | 4005 | 0.036 | 0.4671 | Yes |
| 11 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 4570 | 0.029 | 0.4610 | Yes |
| 12 | CHRNE | CHRNE Entrez, Source | cholinergic receptor, nicotinic, epsilon | 5036 | 0.023 | 0.4553 | Yes |
| 13 | CHRNA6 | CHRNA6 Entrez, Source | cholinergic receptor, nicotinic, alpha 6 | 5046 | 0.023 | 0.4836 | Yes |
| 14 | CHRNA4 | CHRNA4 Entrez, Source | cholinergic receptor, nicotinic, alpha 4 | 5066 | 0.023 | 0.5109 | Yes |
| 15 | P2RX3 | P2RX3 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 3 | 7082 | 0.001 | 0.3611 | No |
| 16 | P2RX1 | P2RX1 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 1 | 7136 | 0.001 | 0.3579 | No |
| 17 | P2RX4 | P2RX4 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 4 | 7423 | -0.003 | 0.3400 | No |
| 18 | CHRNB4 | CHRNB4 Entrez, Source | cholinergic receptor, nicotinic, beta 4 | 8203 | -0.012 | 0.2962 | No |
| 19 | CHRNB2 | CHRNB2 Entrez, Source | cholinergic receptor, nicotinic, beta 2 (neuronal) | 8576 | -0.016 | 0.2889 | No |
| 20 | CHRNB3 | CHRNB3 Entrez, Source | cholinergic receptor, nicotinic, beta 3 | 10962 | -0.055 | 0.1786 | No |
