Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | FASPATHWAY |
| Enrichment Score (ES) | -0.6675533 |
| Normalized Enrichment Score (NES) | -1.7944859 |
| Nominal p-value | 0.0018484289 |
| FDR q-value | 0.04274909 |
| FWER p-Value | 0.98 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 2159 | 0.065 | -0.1112 | No |
| 2 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 6080 | 0.012 | -0.3959 | No |
| 3 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | -0.5379 | No |
| 4 | FAF1 | FAF1 Entrez, Source | Fas (TNFRSF6) associated factor 1 | 8442 | -0.015 | -0.5533 | No |
| 5 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 8465 | -0.015 | -0.5430 | No |
| 6 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 8710 | -0.018 | -0.5472 | No |
| 7 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10315 | -0.042 | -0.6348 | Yes |
| 8 | DFFA | DFFA Entrez, Source | DNA fragmentation factor, 45kDa, alpha polypeptide | 10349 | -0.042 | -0.6040 | Yes |
| 9 | FADD | FADD Entrez, Source | Fas (TNFRSF6)-associated via death domain | 10437 | -0.044 | -0.5760 | Yes |
| 10 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 10643 | -0.048 | -0.5538 | Yes |
| 11 | CASP6 | CASP6 Entrez, Source | caspase 6, apoptosis-related cysteine peptidase | 10778 | -0.051 | -0.5236 | Yes |
| 12 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 11055 | -0.057 | -0.4996 | Yes |
| 13 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 11387 | -0.065 | -0.4735 | Yes |
| 14 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.4233 | Yes |
| 15 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 11446 | -0.066 | -0.3744 | Yes |
| 16 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.3479 | Yes |
| 17 | PAK2 | PAK2 Entrez, Source | p21 (CDKN1A)-activated kinase 2 | 12118 | -0.092 | -0.2840 | Yes |
| 18 | LMNA | LMNA Entrez, Source | lamin A/C | 12554 | -0.122 | -0.2210 | Yes |
| 19 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 12565 | -0.122 | -0.1256 | Yes |
| 20 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 13104 | -0.234 | 0.0179 | Yes |
