Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | FATTY_ACID_METABOLISM |
| Enrichment Score (ES) | 0.59985083 |
| Normalized Enrichment Score (NES) | 2.229774 |
| Nominal p-value | 0.0 |
| FDR q-value | 4.3042042E-4 |
| FWER p-Value | 0.0070 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 6 | 0.447 | 0.0744 | Yes |
| 2 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 10 | 0.411 | 0.1431 | Yes |
| 3 | ACAT2 | ACAT2 Entrez, Source | acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase) | 14 | 0.377 | 0.2061 | Yes |
| 4 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 19 | 0.354 | 0.2651 | Yes |
| 5 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 56 | 0.277 | 0.3088 | Yes |
| 6 | FASN | FASN Entrez, Source | fatty acid synthase | 60 | 0.267 | 0.3534 | Yes |
| 7 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 90 | 0.236 | 0.3908 | Yes |
| 8 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 155 | 0.190 | 0.4178 | Yes |
| 9 | ACAA2 | ACAA2 Entrez, Source | acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase) | 163 | 0.187 | 0.4487 | Yes |
| 10 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 227 | 0.165 | 0.4716 | Yes |
| 11 | ACOX2 | ACOX2 Entrez, Source | acyl-Coenzyme A oxidase 2, branched chain | 442 | 0.130 | 0.4773 | Yes |
| 12 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 469 | 0.128 | 0.4968 | Yes |
| 13 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 507 | 0.124 | 0.5149 | Yes |
| 14 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 564 | 0.121 | 0.5309 | Yes |
| 15 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 670 | 0.114 | 0.5420 | Yes |
| 16 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 840 | 0.105 | 0.5470 | Yes |
| 17 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 975 | 0.099 | 0.5534 | Yes |
| 18 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 1240 | 0.088 | 0.5483 | Yes |
| 19 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 1295 | 0.086 | 0.5586 | Yes |
| 20 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 1443 | 0.081 | 0.5612 | Yes |
| 21 | ECHS1 | ECHS1 Entrez, Source | enoyl Coenzyme A hydratase, short chain, 1, mitochondrial | 1528 | 0.079 | 0.5680 | Yes |
| 22 | ACSL5 | ACSL5 Entrez, Source | acyl-CoA synthetase long-chain family member 5 | 1561 | 0.078 | 0.5787 | Yes |
| 23 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.5845 | Yes |
| 24 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 1719 | 0.074 | 0.5920 | Yes |
| 25 | CYP2C9 | CYP2C9 Entrez, Source | cytochrome P450, family 2, subfamily C, polypeptide 9 | 1777 | 0.073 | 0.5999 | Yes |
| 26 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 1987 | 0.068 | 0.5956 | No |
| 27 | FAAH | FAAH Entrez, Source | fatty acid amide hydrolase | 2116 | 0.066 | 0.5969 | No |
| 28 | PECR | PECR Entrez, Source | peroxisomal trans-2-enoyl-CoA reductase | 2446 | 0.060 | 0.5822 | No |
| 29 | ALDH1A2 | ALDH1A2 Entrez, Source | aldehyde dehydrogenase 1 family, member A2 | 2896 | 0.052 | 0.5570 | No |
| 30 | CYP4B1 | CYP4B1 Entrez, Source | cytochrome P450, family 4, subfamily B, polypeptide 1 | 3238 | 0.047 | 0.5392 | No |
| 31 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 3359 | 0.045 | 0.5377 | No |
| 32 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 3526 | 0.043 | 0.5323 | No |
| 33 | SDS | SDS Entrez, Source | serine dehydratase | 3684 | 0.041 | 0.5273 | No |
| 34 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 3783 | 0.039 | 0.5266 | No |
| 35 | CYP1A2 | CYP1A2 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 2 | 3939 | 0.037 | 0.5212 | No |
| 36 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 4134 | 0.035 | 0.5124 | No |
| 37 | PECI | PECI Entrez, Source | peroxisomal D3,D2-enoyl-CoA isomerase | 4265 | 0.033 | 0.5081 | No |
| 38 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 4313 | 0.032 | 0.5100 | No |
| 39 | ACOX3 | ACOX3 Entrez, Source | acyl-Coenzyme A oxidase 3, pristanoyl | 4732 | 0.027 | 0.4831 | No |
| 40 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 5156 | 0.022 | 0.4549 | No |
| 41 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 5845 | 0.014 | 0.4055 | No |
| 42 | LIPE | LIPE Entrez, Source | lipase, hormone-sensitive | 6156 | 0.011 | 0.3841 | No |
| 43 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 6235 | 0.011 | 0.3800 | No |
| 44 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 7461 | -0.003 | 0.2883 | No |
| 45 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 7949 | -0.009 | 0.2532 | No |
| 46 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 8630 | -0.017 | 0.2049 | No |
| 47 | LPL | LPL Entrez, Source | lipoprotein lipase | 8894 | -0.020 | 0.1885 | No |
| 48 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 9006 | -0.022 | 0.1838 | No |
| 49 | ALDH9A1 | ALDH9A1 Entrez, Source | aldehyde dehydrogenase 9 family, member A1 | 9309 | -0.026 | 0.1654 | No |
| 50 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 9511 | -0.029 | 0.1552 | No |
| 51 | ACADL | ACADL Entrez, Source | acyl-Coenzyme A dehydrogenase, long chain | 9656 | -0.031 | 0.1496 | No |
| 52 | DCI | DCI Entrez, Source | dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase) | 10098 | -0.038 | 0.1228 | No |
| 53 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 10245 | -0.041 | 0.1186 | No |
| 54 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 10268 | -0.041 | 0.1238 | No |
| 55 | ASAH1 | ASAH1 Entrez, Source | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 12530 | -0.120 | -0.0263 | No |
| 56 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 12676 | -0.132 | -0.0152 | No |
| 57 | ALDH1B1 | ALDH1B1 Entrez, Source | aldehyde dehydrogenase 1 family, member B1 | 12682 | -0.133 | 0.0067 | No |
| 58 | FABP7 | FABP7 Entrez, Source | fatty acid binding protein 7, brain | 13148 | -0.256 | 0.0146 | No |
