Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classdouble_gel_48h
GeneSetFLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN
Enrichment Score (ES)0.29472846
Normalized Enrichment Score (NES)1.4332271
Nominal p-value0.0
FDR q-value0.18840228
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase60.4470.0168Yes
2FABP1FABP1
Entrez,  Source
fatty acid binding protein 1, liver100.4110.0325Yes
3G6PCG6PC
Entrez,  Source
glucose-6-phosphatase, catalytic subunit260.3370.0443Yes
4BBOX1BBOX1
Entrez,  Source
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1370.3030.0553Yes
5USP2USP2
Entrez,  Source
ubiquitin specific peptidase 2420.2930.0663Yes
6FBP1FBP1
Entrez,  Source
fructose-1,6-bisphosphatase 1670.2550.0743Yes
7SULT1C1SULT1C1
Entrez,  Source
sulfotransferase family, cytosolic, 1C, member 1690.2550.0841Yes
8SLC34A1SLC34A1
Entrez,  Source
solute carrier family 34 (sodium phosphate), member 1780.2450.0930Yes
9SC4MOLSC4MOL
Entrez,  Source
sterol-C4-methyl oxidase-like900.2360.1012Yes
10GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase1020.2250.1091Yes
11CYP17A1CYP17A1
Entrez,  Source
cytochrome P450, family 17, subfamily A, polypeptide 11030.2200.1176Yes
12ABP1ABP1
Entrez,  Source
amiloride binding protein 1 (amine oxidase (copper-containing))1130.2130.1251Yes
13PLGPLG
Entrez,  Source
plasminogen1200.2060.1326Yes
14AFMAFM
Entrez,  Source
afamin1220.2050.1405Yes
15PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)1480.1930.1460Yes
16KHKKHK
Entrez,  Source
ketohexokinase (fructokinase)1610.1890.1524Yes
17ACAA2ACAA2
Entrez,  Source
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)1630.1870.1595Yes
18SC5DLSC5DL
Entrez,  Source
sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like1870.1760.1646Yes
19GSTA2GSTA2
Entrez,  Source
glutathione S-transferase A21880.1750.1713Yes
20GOT1GOT1
Entrez,  Source
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)1970.1730.1774Yes
21GPC3GPC3
Entrez,  Source
glypican 32210.1670.1821Yes
22ACOX1ACOX1
Entrez,  Source
acyl-Coenzyme A oxidase 1, palmitoyl2270.1650.1881Yes
23ERBB3ERBB3
Entrez,  Source
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)2350.1630.1938Yes
24BHMTBHMT
Entrez,  Source
betaine-homocysteine methyltransferase2370.1620.2000Yes
25DPYSDPYS
Entrez,  Source
dihydropyrimidinase2420.1610.2059Yes
26PTGER3PTGER3
Entrez,  Source
prostaglandin E receptor 3 (subtype EP3)2440.1610.2121Yes
27PCPC
Entrez,  Source
pyruvate carboxylase2700.1550.2161Yes
28ABATABAT
Entrez,  Source
4-aminobutyrate aminotransferase2710.1550.2221Yes
29ALDH6A1ALDH6A1
Entrez,  Source
aldehyde dehydrogenase 6 family, member A13140.1480.2246Yes
30SEPHS2SEPHS2
Entrez,  Source
selenophosphate synthetase 23560.1410.2269Yes
31SLC37A4SLC37A4
Entrez,  Source
solute carrier family 37 (glycerol-6-phosphate transporter), member 43680.1390.2314Yes
32CATCAT
Entrez,  Source
catalase3910.1370.2350Yes
33AZGP1AZGP1
Entrez,  Source
alpha-2-glycoprotein 1, zinc3920.1370.2403Yes
34IGFBP4IGFBP4
Entrez,  Source
insulin-like growth factor binding protein 44060.1350.2444Yes
35RBP4RBP4
Entrez,  Source
retinol binding protein 4, plasma4090.1340.2495Yes
36TSTTST
Entrez,  Source
thiosulfate sulfurtransferase (rhodanese)4460.1300.2517Yes
37FAHFAH
Entrez,  Source
fumarylacetoacetate hydrolase (fumarylacetoacetase)4890.1260.2534Yes
38ENPP2ENPP2
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)5110.1240.2566Yes
39APOMAPOM
Entrez,  Source
apolipoprotein M6280.1170.2521Yes
40EPHX2EPHX2
Entrez,  Source
epoxide hydrolase 2, cytoplasmic6600.1140.2542Yes
41SLC13A3SLC13A3
Entrez,  Source
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 36750.1140.2575Yes
42PRODH2PRODH2
Entrez,  Source
proline dehydrogenase (oxidase) 27080.1110.2593Yes
43AKR7A2AKR7A2
Entrez,  Source
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)7120.1110.2634Yes
44EFHA1EFHA1
Entrez,  Source
EF-hand domain family, member A17830.1080.2621Yes
45FBXO9FBXO9
Entrez,  Source
F-box protein 98100.1060.2642Yes
46PHKBPHKB
Entrez,  Source
phosphorylase kinase, beta8440.1050.2657Yes
47CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)9400.1000.2623Yes
48ALDOBALDOB
Entrez,  Source
aldolase B, fructose-bisphosphate9410.1000.2661Yes
49TOMM70ATOMM70A
Entrez,  Source
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)10340.0960.2628Yes
50MPDZMPDZ
Entrez,  Source
multiple PDZ domain protein10360.0960.2664Yes
51PTPN3PTPN3
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 310850.0940.2663Yes
52GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)11070.0930.2683Yes
53KLKL
Entrez,  Source
klotho11200.0930.2709Yes
54PDZK1IP1PDZK1IP1
Entrez,  Source
PDZK1 interacting protein 111510.0910.2722Yes
55HRSP12HRSP12
Entrez,  Source
heat-responsive protein 1212670.0870.2667Yes
56CTHCTH
Entrez,  Source
cystathionase (cystathionine gamma-lyase)12840.0860.2688Yes
57PEX19PEX19
Entrez,  Source
peroxisomal biogenesis factor 1912910.0860.2716Yes
58ACAT1ACAT1
Entrez,  Source
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)12950.0860.2747Yes
59HPNHPN
Entrez,  Source
hepsin (transmembrane protease, serine 1)13030.0860.2775Yes
60SERPINA5SERPINA5
Entrez,  Source
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 513110.0860.2803Yes
61CA4CA4
Entrez,  Source
carbonic anhydrase IV13880.0830.2776Yes
62HMGCLHMGCL
Entrez,  Source
3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase (hydroxymethylglutaricaciduria)13940.0830.2805Yes
63SLC26A4SLC26A4
Entrez,  Source
solute carrier family 26, member 414090.0820.2826Yes
64APOHAPOH
Entrez,  Source
apolipoprotein H (beta-2-glycoprotein I)14310.0820.2841Yes
65ADH6ADH6
Entrez,  Source
alcohol dehydrogenase 6 (class V)14430.0810.2864Yes
66PAHPAH
Entrez,  Source
phenylalanine hydroxylase15130.0790.2841Yes
67ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial15280.0790.2861Yes
68UGDHUGDH
Entrez,  Source
UDP-glucose dehydrogenase15620.0780.2866Yes
69SLC7A8SLC7A8
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 815840.0770.2879Yes
70AHCYAHCY
Entrez,  Source
S-adenosylhomocysteine hydrolase16120.0770.2888Yes
71OGG1OGG1
Entrez,  Source
8-oxoguanine DNA glycosylase16130.0770.2918Yes
72FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES16820.0750.2894Yes
73LRPPRCLRPPRC
Entrez,  Source
leucine-rich PPR-motif containing17210.0740.2894Yes
74CLDN8CLDN8
Entrez,  Source
claudin 817240.0740.2921Yes
75DNAJB9DNAJB9
Entrez,  Source
DnaJ (Hsp40) homolog, subfamily B, member 917490.0730.2930Yes
76GPSN2GPSN2
Entrez,  Source
glycoprotein, synaptic 217830.0720.2933Yes
77ANPEPANPEP
Entrez,  Source
alanyl (membrane) aminopeptidase (aminopeptidase N, aminopeptidase M, microsomal aminopeptidase, CD13, p150)18760.0700.2889Yes
78VEGFVEGF
Entrez,  Source
vascular endothelial growth factor18830.0700.2912Yes
79AKR7A3AKR7A3
Entrez,  Source
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)19040.0700.2923Yes
80ESRRGESRRG
Entrez,  Source
estrogen-related receptor gamma19090.0700.2947Yes
81QDPRQDPR
Entrez,  Source
quinoid dihydropteridine reductase19670.0690.2930No
82TOB1TOB1
Entrez,  Source
transducer of ERBB2, 121580.0650.2809No
83HBLD2HBLD2
Entrez,  Source
HESB like domain containing 222530.0630.2761No
84CYP4F2CYP4F2
Entrez,  Source
cytochrome P450, family 4, subfamily F, polypeptide 222910.0620.2756No
85TSPYL4TSPYL4
Entrez,  Source
TSPY-like 423080.0620.2768No
86AK3L1AK3L1
Entrez,  Source
adenylate kinase 3-like 123370.0610.2770No
87TNFRSF11BTNFRSF11B
Entrez,  Source
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)23940.0600.2750No
88DEFB1DEFB1
Entrez,  Source
defensin, beta 124010.0600.2769No
89HIBCHHIBCH
Entrez,  Source
3-hydroxyisobutyryl-Coenzyme A hydrolase24420.0600.2761No
90KDRKDR
Entrez,  Source
kinase insert domain receptor (a type III receptor tyrosine kinase)25050.0580.2736No
91CD9CD9
Entrez,  Source
CD9 molecule25270.0580.2742No
92CREB3L2CREB3L2
Entrez,  Source
cAMP responsive element binding protein 3-like 225990.0570.2709No
93IGFBP5IGFBP5
Entrez,  Source
insulin-like growth factor binding protein 526290.0560.2709No
94PIK3R1PIK3R1
Entrez,  Source
phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha)26680.0560.2701No
95HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase26760.0560.2717No
96MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle26960.0550.2724No
97ACY1ACY1
Entrez,  Source
aminoacylase 127220.0550.2726No
98PEX3PEX3
Entrez,  Source
peroxisomal biogenesis factor 327450.0540.2730No
99DDTDDT
Entrez,  Source
D-dopachrome tautomerase27620.0540.2738No
100SLC3A2SLC3A2
Entrez,  Source
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 227770.0540.2748No
101ANKRD46ANKRD46
Entrez,  Source
ankyrin repeat domain 4628000.0530.2752No
102COMTCOMT
Entrez,  Source
catechol-O-methyltransferase28320.0530.2749No
103AKAP11AKAP11
Entrez,  Source
A kinase (PRKA) anchor protein 1128410.0530.2763No
104MDH1MDH1
Entrez,  Source
malate dehydrogenase 1, NAD (soluble)28530.0520.2774No
105ATP5OATP5O
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)28830.0520.2772No
106DZIP1DZIP1
Entrez,  Source
DAZ interacting protein 129280.0510.2758No
107ENTPD5ENTPD5
Entrez,  Source
ectonucleoside triphosphate diphosphohydrolase 529750.0500.2742No
108GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)29970.0500.2745No
109GCHFRGCHFR
Entrez,  Source
GTP cyclohydrolase I feedback regulator30330.0500.2737No
110ASS1ASS1
Entrez,  Source
argininosuccinate synthetase 130630.0490.2734No
111SLC1A1SLC1A1
Entrez,  Source
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 132230.0470.2630No
112DNM1LDNM1L
Entrez,  Source
dynamin 1-like32350.0470.2639No
113EBNA1BP2EBNA1BP2
Entrez,  Source
EBNA1 binding protein 232790.0460.2624No
114SLC17A1SLC17A1
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 132950.0460.2630No
115IGFBP2IGFBP2
Entrez,  Source
insulin-like growth factor binding protein 2, 36kDa33030.0460.2642No
116FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)33150.0460.2652No
117FPGTFPGT
Entrez,  Source
fucose-1-phosphate guanylyltransferase33760.0450.2623No
118STCHSTCH
Entrez,  Source
stress 70 protein chaperone, microsome-associated, 60kDa34000.0440.2622No
119COX7BCOX7B
Entrez,  Source
cytochrome c oxidase subunit VIIb34410.0440.2608No
120WWP1WWP1
Entrez,  Source
WW domain containing E3 ubiquitin protein ligase 134590.0440.2612No
121RRAGARRAGA
Entrez,  Source
Ras-related GTP binding A34660.0430.2624No
122SLC25A1SLC25A1
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 134770.0430.2633No
123ACADSBACADSB
Entrez,  Source
acyl-Coenzyme A dehydrogenase, short/branched chain35260.0430.2613No
124SCP2SCP2
Entrez,  Source
sterol carrier protein 235340.0420.2624No
125SLC31A1SLC31A1
Entrez,  Source
solute carrier family 31 (copper transporters), member 136160.0420.2577No
126CLINT1CLINT1
Entrez,  Source
clathrin interactor 136930.0410.2534No
127CRYAACRYAA
Entrez,  Source
crystallin, alpha A37400.0400.2515No
128ACO2ACO2
Entrez,  Source
aconitase 2, mitochondrial37990.0390.2485No
129APLP2APLP2
Entrez,  Source
amyloid beta (A4) precursor-like protein 238200.0390.2485No
130BCKDHBBCKDHB
Entrez,  Source
branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease)39120.0380.2429No
131HPGDHPGD
Entrez,  Source
hydroxyprostaglandin dehydrogenase 15-(NAD)39150.0380.2442No
132IDH1IDH1
Entrez,  Source
isocitrate dehydrogenase 1 (NADP+), soluble39530.0370.2428No
133AQP1AQP1
Entrez,  Source
aquaporin 1 (Colton blood group)40370.0360.2378No
134NQO2NQO2
Entrez,  Source
NAD(P)H dehydrogenase, quinone 240390.0360.2391No
135MRPS18BMRPS18B
Entrez,  Source
mitochondrial ribosomal protein S18B40530.0360.2395No
136ALDH5A1ALDH5A1
Entrez,  Source
aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)41140.0350.2362No
137GATMGATM
Entrez,  Source
glycine amidinotransferase (L-arginine:glycine amidinotransferase)42290.0330.2287No
138KCNJ15KCNJ15
Entrez,  Source
potassium inwardly-rectifying channel, subfamily J, member 1542960.0330.2249No
139HADHBHADHB
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit43130.0320.2249No
140DDX3XDDX3X
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked43290.0320.2250No
141SLC17A3SLC17A3
Entrez,  Source
solute carrier family 17 (sodium phosphate), member 343380.0320.2256No
142RABGGTBRABGGTB
Entrez,  Source
Rab geranylgeranyltransferase, beta subunit43730.0320.2242No
143ANKRD15ANKRD15
Entrez,  Source
ankyrin repeat domain 1544010.0310.2234No
144DDCDDC
Entrez,  Source
dopa decarboxylase (aromatic L-amino acid decarboxylase)45120.0300.2161No
145CALB1CALB1
Entrez,  Source
calbindin 1, 28kDa45430.0300.2149No
146SDHASDHA
Entrez,  Source
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)45590.0290.2149No
147SLC7A7SLC7A7
Entrez,  Source
solute carrier family 7 (cationic amino acid transporter, y+ system), member 746000.0290.2129No
148SLC22A2SLC22A2
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 246020.0290.2139No
149SMAD5SMAD5
Entrez,  Source
SMAD, mothers against DPP homolog 5 (Drosophila)46070.0290.2147No
150ANK3ANK3
Entrez,  Source
ankyrin 3, node of Ranvier (ankyrin G)46400.0280.2133No
151ASPAASPA
Entrez,  Source
aspartoacylase (Canavan disease)46450.0280.2141No
152ACSM3ACSM3
Entrez,  Source
acyl-CoA synthetase medium-chain family member 346530.0280.2147No
153ACO1ACO1
Entrez,  Source
aconitase 1, soluble46550.0280.2157No
154QPRTQPRT
Entrez,  Source
quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating))46910.0280.2140No
155PEX11BPEX11B
Entrez,  Source
peroxisomal biogenesis factor 11B46990.0280.2146No
156SHMT1SHMT1
Entrez,  Source
serine hydroxymethyltransferase 1 (soluble)47380.0270.2127No
157IGF1RIGF1R
Entrez,  Source
insulin-like growth factor 1 receptor47430.0270.2134No
158NR1D2NR1D2
Entrez,  Source
nuclear receptor subfamily 1, group D, member 247480.0270.2142No
159PHYHPHYH
Entrez,  Source
phytanoyl-CoA 2-hydroxylase48270.0260.2092No
160PTHR1PTHR1
Entrez,  Source
parathyroid hormone receptor 148330.0260.2098No
161FOLH1FOLH1
Entrez,  Source
folate hydrolase (prostate-specific membrane antigen) 148550.0260.2091No
162NR3C2NR3C2
Entrez,  Source
nuclear receptor subfamily 3, group C, member 249470.0250.2031No
163CDKN1CCDKN1C
Entrez,  Source
cyclin-dependent kinase inhibitor 1C (p57, Kip2)50200.0240.1984No
164UQCRC2UQCRC2
Entrez,  Source
ubiquinol-cytochrome c reductase core protein II50220.0240.1993No
165ATP5A1ATP5A1
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle51490.0220.1904No
166MAOAMAOA
Entrez,  Source
monoamine oxidase A51770.0220.1892No
167HSPE1HSPE1
Entrez,  Source
heat shock 10kDa protein 1 (chaperonin 10)52180.0210.1869No
168PGRMC2PGRMC2
Entrez,  Source
progesterone receptor membrane component 253450.0200.1780No
169NDUFS1NDUFS1
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)54210.0190.1730No
170VDAC2VDAC2
Entrez,  Source
voltage-dependent anion channel 254560.0190.1711No
171SDHCSDHC
Entrez,  Source
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa55220.0180.1667No
172ABCC4ABCC4
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 455430.0180.1659No
173PRPSAP2PRPSAP2
Entrez,  Source
phosphoribosyl pyrophosphate synthetase-associated protein 255650.0180.1650No
174PCBD1PCBD1
Entrez,  Source
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)55910.0170.1637No
175SLC12A3SLC12A3
Entrez,  Source
solute carrier family 12 (sodium/chloride transporters), member 356410.0170.1606No
176HSPD1HSPD1
Entrez,  Source
heat shock 60kDa protein 1 (chaperonin)56620.0160.1597No
177GHITMGHITM
Entrez,  Source
growth hormone inducible transmembrane protein57260.0160.1554No
178UQCRFS1UQCRFS1
Entrez,  Source
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 157490.0150.1543No
179NARSNARS
Entrez,  Source
asparaginyl-tRNA synthetase57870.0150.1521No
180ACADMACADM
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain58450.0140.1482No
181SLC22A6SLC22A6
Entrez,  Source
solute carrier family 22 (organic anion transporter), member 658650.0140.1473No
182BAMBIBAMBI
Entrez,  Source
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)58740.0140.1472No
183DLDDLD
Entrez,  Source
dihydrolipoamide dehydrogenase58760.0140.1477No
184HSD11B2HSD11B2
Entrez,  Source
hydroxysteroid (11-beta) dehydrogenase 259600.0130.1418No
185PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)59900.0130.1401No
186HNMTHNMT
Entrez,  Source
histamine N-methyltransferase60100.0130.1391No
187CDH1CDH1
Entrez,  Source
cadherin 1, type 1, E-cadherin (epithelial)60860.0120.1338No
188SHANK2SHANK2
Entrez,  Source
SH3 and multiple ankyrin repeat domains 261460.0110.1297No
189PPM1BPPM1B
Entrez,  Source
protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform61650.0110.1287No
190ETFAETFA
Entrez,  Source
electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II)61870.0110.1276No
191PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase61880.0110.1280No
192STRAPSTRAP
Entrez,  Source
serine/threonine kinase receptor associated protein62060.0110.1271No
193RNF14RNF14
Entrez,  Source
ring finger protein 1462770.0100.1221No
194TEGTTEGT
Entrez,  Source
testis enhanced gene transcript (BAX inhibitor 1)62840.0100.1220No
195COPS5COPS5
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)63060.0100.1208No
196UQCRC1UQCRC1
Entrez,  Source
ubiquinol-cytochrome c reductase core protein I63940.0090.1144No
197CDS1CDS1
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 164140.0080.1133No
198ADD3ADD3
Entrez,  Source
adducin 3 (gamma)64720.0080.1092No
199PGRMC1PGRMC1
Entrez,  Source
progesterone receptor membrane component 165420.0070.1041No
200COPACOPA
Entrez,  Source
coatomer protein complex, subunit alpha66180.0060.0986No
201PDE8APDE8A
Entrez,  Source
phosphodiesterase 8A66860.0060.0937No
202TACSTD1TACSTD1
Entrez,  Source
tumor-associated calcium signal transducer 167200.0050.0913No
203ZNF148ZNF148
Entrez,  Source
zinc finger protein 14867510.0050.0892No
204AKR1A1AKR1A1
Entrez,  Source
aldo-keto reductase family 1, member A1 (aldehyde reductase)68690.0030.0803No
205ALBALB
Entrez,  Source
albumin68880.0030.0790No
206YWHAEYWHAE
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide69040.0030.0780No
207RAB7L1RAB7L1
Entrez,  Source
RAB7, member RAS oncogene family-like 169230.0030.0767No
208CYCSCYCS
Entrez,  Source
cytochrome c, somatic69370.0030.0758No
209PDCD8PDCD8
Entrez,  Source
programmed cell death 8 (apoptosis-inducing factor)70010.0020.0710No
210RFKRFK
Entrez,  Source
riboflavin kinase70260.0020.0693No
211PHBPHB
Entrez,  Source
prohibitin70280.0020.0692No
212CA2CA2
Entrez,  Source
carbonic anhydrase II70340.0020.0689No
213TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)71490.0000.0602No
214RAB1ARAB1A
Entrez,  Source
RAB1A, member RAS oncogene family7222-0.0000.0546No
215PEBP1PEBP1
Entrez,  Source
phosphatidylethanolamine binding protein 17255-0.0010.0522No
216CGRRF1CGRRF1
Entrez,  Source
cell growth regulator with ring finger domain 17267-0.0010.0514No
217FMO1FMO1
Entrez,  Source
flavin containing monooxygenase 17292-0.0010.0496No
218PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha7310-0.0020.0483No
219PGM1PGM1
Entrez,  Source
phosphoglucomutase 17335-0.0020.0466No
220MORF4L2MORF4L2
Entrez,  Source
mortality factor 4 like 27356-0.0020.0451No
221SERBP1SERBP1
Entrez,  Source
SERPINE1 mRNA binding protein 17386-0.0020.0430No
222CYB5ACYB5A
Entrez,  Source
cytochrome b5 type A (microsomal)7424-0.0030.0402No
223CRYMCRYM
Entrez,  Source
crystallin, mu7438-0.0030.0393No
224PRDX3PRDX3
Entrez,  Source
peroxiredoxin 37459-0.0030.0379No
225PDZK1PDZK1
Entrez,  Source
PDZ domain containing 17531-0.0040.0326No
226HSPB1HSPB1
Entrez,  Source
heat shock 27kDa protein 17586-0.0050.0286No
227COPS2COPS2
Entrez,  Source
COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)7649-0.0050.0241No
228TOMM20TOMM20
Entrez,  Source
translocase of outer mitochondrial membrane 20 homolog (yeast)7655-0.0050.0239No
229UGT8UGT8
Entrez,  Source
UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase)7727-0.0060.0187No
230HADHHADH
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase7824-0.0070.0115No
231ATF2ATF2
Entrez,  Source
activating transcription factor 27856-0.0080.0095No
232PEX7PEX7
Entrez,  Source
peroxisomal biogenesis factor 77894-0.0080.0069No
233SORDSORD
Entrez,  Source
sorbitol dehydrogenase7900-0.0080.0069No
234PRKAR1APRKAR1A
Entrez,  Source
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)7920-0.0090.0057No
235COX6A1COX6A1
Entrez,  Source
cytochrome c oxidase subunit VIa polypeptide 17932-0.0090.0052No
236GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 18014-0.010-0.0007No
237OATOAT
Entrez,  Source
ornithine aminotransferase (gyrate atrophy)8046-0.010-0.0027No
238C1QBPC1QBP
Entrez,  Source
complement component 1, q subcomponent binding protein8127-0.011-0.0084No
239ECH1ECH1
Entrez,  Source
enoyl Coenzyme A hydratase 1, peroxisomal8150-0.011-0.0097No
240PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa8159-0.011-0.0098No
241GPR116GPR116
Entrez,  Source
G protein-coupled receptor 1168170-0.011-0.0102No
242CTSLCTSL
Entrez,  Source
cathepsin L8194-0.012-0.0115No
243HPDHPD
Entrez,  Source
4-hydroxyphenylpyruvate dioxygenase8248-0.012-0.0151No
244VDAC1VDAC1
Entrez,  Source
voltage-dependent anion channel 18265-0.013-0.0158No
245IMMTIMMT
Entrez,  Source
inner membrane protein, mitochondrial (mitofilin)8340-0.013-0.0210No
246NAT8NAT8
Entrez,  Source
N-acetyltransferase 8 (camello like)8409-0.014-0.0257No
247ST13ST13
Entrez,  Source
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)8448-0.015-0.0280No
248ATP5JATP5J
Entrez,  Source
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F68485-0.015-0.0302No
249PMPCBPMPCB
Entrez,  Source
peptidase (mitochondrial processing) beta8522-0.016-0.0324No
250NDUFA5NDUFA5
Entrez,  Source
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5, 13kDa8599-0.017-0.0376No
251ALDH2ALDH2
Entrez,  Source
aldehyde dehydrogenase 2 family (mitochondrial)8630-0.017-0.0392No
252DPP4DPP4
Entrez,  Source
dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2)8651-0.017-0.0401No
253SERINC1SERINC1
Entrez,  Source
serine incorporator 18655-0.018-0.0397No
254PPP2R1APPP2R1A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform8667-0.018-0.0398No
255BNIP3BNIP3
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 38690-0.018-0.0408No
256RAB2RAB2
Entrez,  Source
RAB2, member RAS oncogene family8693-0.018-0.0403No
257MAOBMAOB
Entrez,  Source
monoamine oxidase B8794-0.019-0.0472No
258TMED5TMED5
Entrez,  Source
transmembrane emp24 protein transport domain containing 58849-0.020-0.0506No
259HSPA8HSPA8
Entrez,  Source
heat shock 70kDa protein 88850-0.020-0.0499No
260CLTBCLTB
Entrez,  Source
clathrin, light chain (Lcb)8851-0.020-0.0491No
261PFN2PFN2
Entrez,  Source
profilin 28946-0.021-0.0555No
262MINPP1MINPP1
Entrez,  Source
multiple inositol polyphosphate histidine phosphatase, 18960-0.021-0.0557No
263G3BPG3BP
Entrez,  Source
-9008-0.022-0.0585No
264GLSGLS
Entrez,  Source
glutaminase9032-0.022-0.0594No
265SOD1SOD1
Entrez,  Source
superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))9099-0.023-0.0636No
266NDUFS4NDUFS4
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)9118-0.023-0.0640No
267CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 29145-0.024-0.0651No
268RDXRDX
Entrez,  Source
radixin9216-0.025-0.0696No
269ALDH9A1ALDH9A1
Entrez,  Source
aldehyde dehydrogenase 9 family, member A19309-0.026-0.0757No
270MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)9318-0.026-0.0753No
271PRDX2PRDX2
Entrez,  Source
peroxiredoxin 29329-0.026-0.0750No
272PGK1PGK1
Entrez,  Source
phosphoglycerate kinase 19333-0.026-0.0742No
273BPHLBPHL
Entrez,  Source
biphenyl hydrolase-like (serine hydrolase; breast epithelial mucin-associated antigen)9370-0.027-0.0760No
274ALDH3A2ALDH3A2
Entrez,  Source
aldehyde dehydrogenase 3 family, member A29511-0.029-0.0856No
275ITM2BITM2B
Entrez,  Source
integral membrane protein 2B9609-0.031-0.0919No
276HDGFHDGF
Entrez,  Source
hepatoma-derived growth factor (high-mobility group protein 1-like)9633-0.031-0.0925No
277AQP3AQP3
Entrez,  Source
aquaporin 3 (Gill blood group)9650-0.031-0.0925No
278ATP2A2ATP2A2
Entrez,  Source
ATPase, Ca++ transporting, cardiac muscle, slow twitch 29652-0.031-0.0914No
279TNPO1TNPO1
Entrez,  Source
transportin 19694-0.032-0.0933No
280NCKAP1NCKAP1
Entrez,  Source
NCK-associated protein 19794-0.033-0.0996No
281CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 49801-0.033-0.0988No
282CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)9898-0.035-0.1048No
283PCBP2PCBP2
Entrez,  Source
poly(rC) binding protein 210046-0.038-0.1147No
284DCIDCI
Entrez,  Source
dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenzyme A isomerase)10098-0.038-0.1172No
285CFDP1CFDP1
Entrez,  Source
craniofacial development protein 110148-0.039-0.1194No
286CYB5R3CYB5R3
Entrez,  Source
cytochrome b5 reductase 310221-0.040-0.1234No
287SNRPN /// SNURF10327-0.042-0.1299No
288SERPINI1SERPINI1
Entrez,  Source
serpin peptidase inhibitor, clade I (neuroserpin), member 110346-0.042-0.1296No
289PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform10348-0.042-0.1281No
290ARMCX2ARMCX2
Entrez,  Source
armadillo repeat containing, X-linked 210401-0.044-0.1304No
291SMAD4SMAD4
Entrez,  Source
SMAD, mothers against DPP homolog 4 (Drosophila)10473-0.045-0.1341No
292USP14USP14
Entrez,  Source
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)10480-0.045-0.1329No
293CALM1CALM1
Entrez,  Source
calmodulin 1 (phosphorylase kinase, delta)10481-0.045-0.1311No
294AP3D1AP3D1
Entrez,  Source
adaptor-related protein complex 3, delta 1 subunit10488-0.045-0.1299No
295ANXA7ANXA7
Entrez,  Source
annexin A710592-0.047-0.1360No
296CBR4CBR4
Entrez,  Source
carbonyl reductase 410676-0.049-0.1405No
297ACPPACPP
Entrez,  Source
acid phosphatase, prostate10827-0.052-0.1500No
298MXI1MXI1
Entrez,  Source
MAX interactor 110848-0.053-0.1495No
299COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 410867-0.053-0.1489No
300ABCD3ABCD3
Entrez,  Source
ATP-binding cassette, sub-family D (ALD), member 310872-0.053-0.1471No
301NEK4NEK4
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 411042-0.057-0.1580No
302PJA2PJA2
Entrez,  Source
praja 2, RING-H2 motif containing11072-0.057-0.1580No
303ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 1111091-0.058-0.1571No
304STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 311105-0.058-0.1559No
305SCAMP1SCAMP1
Entrez,  Source
secretory carrier membrane protein 111279-0.062-0.1668No
306SLC4A4SLC4A4
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 411283-0.062-0.1647No
307PODXLPODXL
Entrez,  Source
podocalyxin-like11359-0.064-0.1680No
308CTBP1CTBP1
Entrez,  Source
C-terminal binding protein 111368-0.064-0.1661No
309KIF3AKIF3A
Entrez,  Source
kinesin family member 3A11486-0.068-0.1725No
310FAM3CFAM3C
Entrez,  Source
family with sequence similarity 3, member C11530-0.070-0.1731No
311PTPRDPTPRD
Entrez,  Source
protein tyrosine phosphatase, receptor type, D11551-0.070-0.1720No
312SDC1SDC1
Entrez,  Source
syndecan 111699-0.075-0.1804No
313RNASE4RNASE4
Entrez,  Source
ribonuclease, RNase A family, 411851-0.081-0.1889No
314LRP2LRP2
Entrez,  Source
low density lipoprotein-related protein 211861-0.081-0.1864No
315DAPDAP
Entrez,  Source
death-associated protein11879-0.082-0.1845No
316BEXL1BEXL1
Entrez,  Source
brain expressed X-linked-like 111912-0.084-0.1838No
317LRPAP1LRPAP1
Entrez,  Source
low density lipoprotein receptor-related protein associated protein 112044-0.089-0.1904No
318FMR1FMR1
Entrez,  Source
fragile X mental retardation 112093-0.091-0.1906No
319CRYZCRYZ
Entrez,  Source
crystallin, zeta (quinone reductase)12135-0.093-0.1901No
320PLS3PLS3
Entrez,  Source
plastin 3 (T isoform)12156-0.094-0.1880No
321DSCR1DSCR1
Entrez,  Source
Down syndrome critical region gene 112190-0.096-0.1868No
322DSPDSP
Entrez,  Source
desmoplakin12225-0.098-0.1857No
323GGHGGH
Entrez,  Source
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)12243-0.099-0.1831No
324PRKCIPRKCI
Entrez,  Source
protein kinase C, iota12255-0.100-0.1801No
325MFAP3LMFAP3L
Entrez,  Source
microfibrillar-associated protein 3-like12284-0.102-0.1783No
326ENPEPENPEP
Entrez,  Source
glutamyl aminopeptidase (aminopeptidase A)12336-0.106-0.1782No
327IMPA2IMPA2
Entrez,  Source
inositol(myo)-1(or 4)-monophosphatase 212423-0.112-0.1805No
328HTRA1HTRA1
Entrez,  Source
HtrA serine peptidase 112456-0.115-0.1785No
329MYH10MYH10
Entrez,  Source
myosin, heavy chain 10, non-muscle12486-0.117-0.1762No
330VAT1VAT1
Entrez,  Source
vesicle amine transport protein 1 homolog (T californica)12596-0.125-0.1798No
331FGF1FGF1
Entrez,  Source
fibroblast growth factor 1 (acidic)12602-0.125-0.1753No
332ABCC2ABCC2
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 212612-0.126-0.1711No
333SMPDL3ASMPDL3A
Entrez,  Source
sphingomyelin phosphodiesterase, acid-like 3A12687-0.133-0.1717No
334HRASLS3HRASLS3
Entrez,  Source
HRAS-like suppressor 312707-0.136-0.1679No
335DSTNDSTN
Entrez,  Source
destrin (actin depolymerizing factor)12710-0.136-0.1628No
336ITGA6ITGA6
Entrez,  Source
integrin, alpha 612716-0.137-0.1579No
337SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 112740-0.140-0.1543No
338WEE1WEE1
Entrez,  Source
WEE1 homolog (S. pombe)12774-0.145-0.1512No
339TSC22D1TSC22D1
Entrez,  Source
TSC22 domain family, member 112825-0.152-0.1492No
340TRIM2TRIM2
Entrez,  Source
tripartite motif-containing 212840-0.154-0.1443No
341GRB14GRB14
Entrez,  Source
growth factor receptor-bound protein 1412905-0.167-0.1428No
342XPNPEP2XPNPEP2
Entrez,  Source
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound12937-0.173-0.1386No
343SLC25A4SLC25A4
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 412996-0.187-0.1358No
344PRKRAPRKRA
Entrez,  Source
protein kinase, interferon-inducible double stranded RNA dependent activator13016-0.194-0.1298No
345RGNRGN
Entrez,  Source
regucalcin (senescence marker protein-30)13030-0.199-0.1231No
346LGALS2LGALS2
Entrez,  Source
lectin, galactoside-binding, soluble, 2 (galectin 2)13064-0.214-0.1174No
347MAFMAF
Entrez,  Source
v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)13083-0.223-0.1101No
348PRNPPRNP
Entrez,  Source
prion protein (p27-30) (Creutzfeldt-Jakob disease, Gerstmann-Strausler-Scheinker syndrome, fatal familial insomnia)13090-0.227-0.1018No
349GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)13121-0.240-0.0949No
350DAB2DAB2
Entrez,  Source
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)13130-0.247-0.0859No
351HSPA4HSPA4
Entrez,  Source
heat shock 70kDa protein 413162-0.265-0.0781No
352RTN4RTN4
Entrez,  Source
reticulon 413167-0.269-0.0680No
353CRYABCRYAB
Entrez,  Source
crystallin, alpha B13206-0.298-0.0594No
354F2RF2R
Entrez,  Source
coagulation factor II (thrombin) receptor13224-0.321-0.0484No
355PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513230-0.326-0.0362No
356NDRG1NDRG1
Entrez,  Source
N-myc downstream regulated gene 113242-0.345-0.0237No
357MMEMME
Entrez,  Source
membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)13245-0.347-0.0104No
358PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha13298-0.4610.0034No
Table: GSEA details [plain text format]



Fig 2: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN: Random ES distribution   
Gene set null distribution of ES for FLECHNER_KIDNEY_TRANSPLANT_REJECTION_DN