Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | FRASOR_ER_DN |
| Enrichment Score (ES) | -0.53431225 |
| Normalized Enrichment Score (NES) | -1.745842 |
| Nominal p-value | 0.0016286644 |
| FDR q-value | 0.05063896 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 40 | 0.295 | 0.0622 | No |
| 2 | PVALB | PVALB Entrez, Source | parvalbumin | 738 | 0.109 | 0.0339 | No |
| 3 | ENC1 | ENC1 Entrez, Source | ectodermal-neural cortex (with BTB-like domain) | 1106 | 0.093 | 0.0269 | No |
| 4 | DUSP4 | DUSP4 Entrez, Source | dual specificity phosphatase 4 | 1225 | 0.089 | 0.0376 | No |
| 5 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 1441 | 0.081 | 0.0394 | No |
| 6 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 1727 | 0.074 | 0.0342 | No |
| 7 | MB | MB Entrez, Source | myoglobin | 2146 | 0.065 | 0.0171 | No |
| 8 | BCAS1 | BCAS1 Entrez, Source | breast carcinoma amplified sequence 1 | 2342 | 0.061 | 0.0160 | No |
| 9 | TRG@ | TRG@ Entrez, Source | T cell receptor gamma locus | 2468 | 0.059 | 0.0196 | No |
| 10 | BLNK | BLNK Entrez, Source | B-cell linker | 3887 | 0.038 | -0.0786 | No |
| 11 | EPOR | EPOR Entrez, Source | erythropoietin receptor | 3955 | 0.037 | -0.0755 | No |
| 12 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 4061 | 0.035 | -0.0755 | No |
| 13 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 4580 | 0.029 | -0.1081 | No |
| 14 | SLIT2 | SLIT2 Entrez, Source | slit homolog 2 (Drosophila) | 4685 | 0.028 | -0.1098 | No |
| 15 | FOLH1 | FOLH1 Entrez, Source | folate hydrolase (prostate-specific membrane antigen) 1 | 4855 | 0.026 | -0.1169 | No |
| 16 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 5117 | 0.022 | -0.1315 | No |
| 17 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | -0.1448 | No |
| 18 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 6204 | 0.011 | -0.2064 | No |
| 19 | ABCC5 | ABCC5 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6552 | 0.007 | -0.2309 | No |
| 20 | ARNT2 | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 6735 | 0.005 | -0.2435 | No |
| 21 | L1CAM | L1CAM Entrez, Source | L1 cell adhesion molecule | 6912 | 0.003 | -0.2561 | No |
| 22 | PIB5PA | PIB5PA Entrez, Source | phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A | 7052 | 0.001 | -0.2662 | No |
| 23 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 7146 | 0.000 | -0.2731 | No |
| 24 | STXBP1 | STXBP1 Entrez, Source | syntaxin binding protein 1 | 7412 | -0.003 | -0.2925 | No |
| 25 | STC1 | STC1 Entrez, Source | stanniocalcin 1 | 8140 | -0.011 | -0.3447 | No |
| 26 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 8150 | -0.011 | -0.3429 | No |
| 27 | CTSL | CTSL Entrez, Source | cathepsin L | 8194 | -0.012 | -0.3436 | No |
| 28 | FMO5 | FMO5 Entrez, Source | flavin containing monooxygenase 5 | 8756 | -0.019 | -0.3816 | No |
| 29 | MYO1B | MYO1B Entrez, Source | myosin IB | 9460 | -0.028 | -0.4282 | No |
| 30 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 10292 | -0.041 | -0.4816 | No |
| 31 | IER3 | IER3 Entrez, Source | immediate early response 3 | 10439 | -0.044 | -0.4829 | No |
| 32 | IFI30 | IFI30 Entrez, Source | interferon, gamma-inducible protein 30 | 10696 | -0.049 | -0.4912 | No |
| 33 | ERBB2 | ERBB2 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 10906 | -0.054 | -0.4951 | No |
| 34 | CTSH | CTSH Entrez, Source | cathepsin H | 11083 | -0.058 | -0.4956 | No |
| 35 | BIK | BIK Entrez, Source | BCL2-interacting killer (apoptosis-inducing) | 11095 | -0.058 | -0.4836 | No |
| 36 | GNS | GNS Entrez, Source | glucosamine (N-acetyl)-6-sulfatase (Sanfilippo disease IIID) | 11302 | -0.062 | -0.4853 | No |
| 37 | CLU | CLU Entrez, Source | clusterin | 11686 | -0.075 | -0.4976 | No |
| 38 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 11763 | -0.078 | -0.4862 | No |
| 39 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 12404 | -0.111 | -0.5097 | Yes |
| 40 | LAMB2 | LAMB2 Entrez, Source | laminin, beta 2 (laminin S) | 12523 | -0.119 | -0.4923 | Yes |
| 41 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 12740 | -0.140 | -0.4777 | Yes |
| 42 | ANXA3 | ANXA3 Entrez, Source | annexin A3 | 13112 | -0.236 | -0.4534 | Yes |
| 43 | ABCG1 | ABCG1 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 1 | 13136 | -0.250 | -0.3998 | Yes |
| 44 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13142 | -0.253 | -0.3443 | Yes |
| 45 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13242 | -0.345 | -0.2756 | Yes |
| 46 | DBN1 | DBN1 Entrez, Source | drebrin 1 | 13305 | -0.475 | -0.1754 | Yes |
| 47 | CD24 | CD24 Entrez, Source | CD24 molecule | 13336 | -0.806 | 0.0005 | Yes |
