Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | G13_SIGNALING_PATHWAY |
| Enrichment Score (ES) | -0.5982326 |
| Normalized Enrichment Score (NES) | -1.7097017 |
| Nominal p-value | 0.010791367 |
| FDR q-value | 0.06316357 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RTKN | RTKN Entrez, Source | rhotekin | 2071 | 0.066 | -0.1057 | No |
| 2 | RPS6KB1 | RPS6KB1 Entrez, Source | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 4614 | 0.028 | -0.2753 | No |
| 3 | PPP1CB | PPP1CB Entrez, Source | protein phosphatase 1, catalytic subunit, beta isoform | 5113 | 0.022 | -0.2958 | No |
| 4 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 5375 | 0.020 | -0.3008 | No |
| 5 | MYBPH | MYBPH Entrez, Source | myosin binding protein H | 5894 | 0.014 | -0.3292 | No |
| 6 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 6080 | 0.012 | -0.3340 | No |
| 7 | MAPK10 | MAPK10 Entrez, Source | mitogen-activated protein kinase 10 | 6962 | 0.002 | -0.3985 | No |
| 8 | PAK3 | PAK3 Entrez, Source | p21 (CDKN1A)-activated kinase 3 | 7555 | -0.004 | -0.4396 | No |
| 9 | PIK3CB | PIK3CB Entrez, Source | phosphoinositide-3-kinase, catalytic, beta polypeptide | 8066 | -0.010 | -0.4703 | No |
| 10 | MCRS1 | MCRS1 Entrez, Source | microspherule protein 1 | 9771 | -0.033 | -0.5735 | Yes |
| 11 | ROCK1 | ROCK1 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 1 | 9904 | -0.035 | -0.5572 | Yes |
| 12 | PKN1 | PKN1 Entrez, Source | protein kinase N1 | 10278 | -0.041 | -0.5545 | Yes |
| 13 | PFN1 | PFN1 Entrez, Source | profilin 1 | 10319 | -0.042 | -0.5261 | Yes |
| 14 | CALM1 | CALM1 Entrez, Source | calmodulin 1 (phosphorylase kinase, delta) | 10481 | -0.045 | -0.5046 | Yes |
| 15 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 10584 | -0.047 | -0.4772 | Yes |
| 16 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 10703 | -0.049 | -0.4490 | Yes |
| 17 | LIMK1 | LIMK1 Entrez, Source | LIM domain kinase 1 | 10751 | -0.051 | -0.4145 | Yes |
| 18 | ARHGEF1 | ARHGEF1 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 1 | 10799 | -0.052 | -0.3794 | Yes |
| 19 | PIK3R2 | PIK3R2 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta) | 10802 | -0.052 | -0.3408 | Yes |
| 20 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 10939 | -0.055 | -0.3101 | Yes |
| 21 | CALM3 | CALM3 Entrez, Source | calmodulin 3 (phosphorylase kinase, delta) | 10959 | -0.055 | -0.2702 | Yes |
| 22 | PIP5K2A | PIP5K2A Entrez, Source | phosphatidylinositol-4-phosphate 5-kinase, type II, alpha | 11119 | -0.058 | -0.2384 | Yes |
| 23 | WASL | WASL Entrez, Source | Wiskott-Aldrich syndrome-like | 11892 | -0.083 | -0.2342 | Yes |
| 24 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 12036 | -0.089 | -0.1783 | Yes |
| 25 | CFL1 | CFL1 Entrez, Source | cofilin 1 (non-muscle) | 12205 | -0.097 | -0.1181 | Yes |
| 26 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12599 | -0.125 | -0.0538 | Yes |
| 27 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 12788 | -0.146 | 0.0416 | Yes |
