Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | G1PATHWAY |
| Enrichment Score (ES) | -0.6633342 |
| Normalized Enrichment Score (NES) | -1.7903763 |
| Nominal p-value | 0.0054054055 |
| FDR q-value | 0.04352547 |
| FWER p-Value | 0.982 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 883 | 0.103 | 0.0023 | No |
| 2 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.2792 | No |
| 3 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 5353 | 0.020 | -0.3030 | No |
| 4 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 5568 | 0.017 | -0.3075 | No |
| 5 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.3151 | No |
| 6 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 6019 | 0.013 | -0.3229 | No |
| 7 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 7053 | 0.001 | -0.3995 | No |
| 8 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7469 | -0.003 | -0.4284 | No |
| 9 | CDK6 | CDK6 Entrez, Source | cyclin-dependent kinase 6 | 8604 | -0.017 | -0.5023 | No |
| 10 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5577 | No |
| 11 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 11022 | -0.056 | -0.6260 | Yes |
| 12 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.6112 | Yes |
| 13 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.5808 | Yes |
| 14 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 11670 | -0.074 | -0.5328 | Yes |
| 15 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12064 | -0.090 | -0.5027 | Yes |
| 16 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12294 | -0.103 | -0.4516 | Yes |
| 17 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 13022 | -0.195 | -0.3767 | Yes |
| 18 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13142 | -0.253 | -0.2181 | Yes |
| 19 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13250 | -0.352 | 0.0069 | Yes |
