Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | G1_TO_S_CELL_CYCLE_REACTOME |
| Enrichment Score (ES) | -0.658521 |
| Normalized Enrichment Score (NES) | -2.102723 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0036780958 |
| FWER p-Value | 0.041 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 1896 | 0.070 | -0.1214 | No |
| 2 | GBA2 | GBA2 Entrez, Source | glucosidase, beta (bile acid) 2 | 3630 | 0.041 | -0.2393 | No |
| 3 | CCNH | CCNH Entrez, Source | cyclin H | 4088 | 0.035 | -0.2630 | No |
| 4 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.2657 | No |
| 5 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4860 | 0.026 | -0.3032 | No |
| 6 | CREB3L1 | CREB3L1 Entrez, Source | cAMP responsive element binding protein 3-like 1 | 4976 | 0.024 | -0.3046 | No |
| 7 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 5020 | 0.024 | -0.3007 | No |
| 8 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.3059 | No |
| 9 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 5568 | 0.017 | -0.3299 | No |
| 10 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.3405 | No |
| 11 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.3382 | No |
| 12 | CREB3L3 | CREB3L3 Entrez, Source | cAMP responsive element binding protein 3-like 3 | 5890 | 0.014 | -0.3406 | No |
| 13 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 6017 | 0.013 | -0.3462 | No |
| 14 | CCNA1 | CCNA1 Entrez, Source | cyclin A1 | 6019 | 0.013 | -0.3425 | No |
| 15 | CREB3L4 | CREB3L4 Entrez, Source | cAMP responsive element binding protein 3-like 4 | 6879 | 0.003 | -0.4061 | No |
| 16 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7160 | 0.000 | -0.4271 | No |
| 17 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 7469 | -0.003 | -0.4492 | No |
| 18 | ORC4L | ORC4L Entrez, Source | origin recognition complex, subunit 4-like (yeast) | 8232 | -0.012 | -0.5028 | No |
| 19 | E2F5 | E2F5 Entrez, Source | E2F transcription factor 5, p130-binding | 8663 | -0.018 | -0.5299 | No |
| 20 | CDK7 | CDK7 Entrez, Source | cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase) | 9024 | -0.022 | -0.5502 | No |
| 21 | ORC3L | ORC3L Entrez, Source | origin recognition complex, subunit 3-like (yeast) | 9431 | -0.028 | -0.5724 | No |
| 22 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 9613 | -0.031 | -0.5767 | No |
| 23 | ORC6L | ORC6L Entrez, Source | origin recognition complex, subunit 6 like (yeast) | 10702 | -0.049 | -0.6436 | Yes |
| 24 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10779 | -0.051 | -0.6339 | Yes |
| 25 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 11022 | -0.056 | -0.6351 | Yes |
| 26 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 11046 | -0.057 | -0.6196 | Yes |
| 27 | CREBL1 | CREBL1 Entrez, Source | cAMP responsive element binding protein-like 1 | 11248 | -0.061 | -0.6163 | Yes |
| 28 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.6080 | Yes |
| 29 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.6044 | Yes |
| 30 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 11760 | -0.077 | -0.5892 | Yes |
| 31 | ORC1L | ORC1L Entrez, Source | origin recognition complex, subunit 1-like (yeast) | 11803 | -0.079 | -0.5685 | Yes |
| 32 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 11809 | -0.080 | -0.5448 | Yes |
| 33 | CDKN2A | CDKN2A Entrez, Source | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 12064 | -0.090 | -0.5368 | Yes |
| 34 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12091 | -0.091 | -0.5112 | Yes |
| 35 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 12106 | -0.092 | -0.4846 | Yes |
| 36 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12271 | -0.101 | -0.4664 | Yes |
| 37 | CDK4 | CDK4 Entrez, Source | cyclin-dependent kinase 4 | 12294 | -0.103 | -0.4370 | Yes |
| 38 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 12513 | -0.118 | -0.4177 | Yes |
| 39 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12774 | -0.145 | -0.3937 | Yes |
| 40 | CREB3 | CREB3 Entrez, Source | cAMP responsive element binding protein 3 | 12976 | -0.184 | -0.3534 | Yes |
| 41 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 13022 | -0.195 | -0.2978 | Yes |
| 42 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | -0.2317 | Yes |
| 43 | CCND1 | CCND1 Entrez, Source | cyclin D1 | 13250 | -0.352 | -0.1348 | Yes |
| 44 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | 0.0031 | Yes |
