Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | GCACCTT,MIR-18A,MIR-18B |
| Enrichment Score (ES) | -0.578216 |
| Normalized Enrichment Score (NES) | -1.823874 |
| Nominal p-value | 0.0016949152 |
| FDR q-value | 0.03788299 |
| FWER p-Value | 0.936 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GCLC | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 1237 | 0.088 | -0.0642 | No |
| 2 | GLRB | GLRB Entrez, Source | glycine receptor, beta | 1617 | 0.077 | -0.0678 | No |
| 3 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 2098 | 0.066 | -0.0823 | No |
| 4 | PACSIN1 | PACSIN1 Entrez, Source | protein kinase C and casein kinase substrate in neurons 1 | 3503 | 0.043 | -0.1739 | No |
| 5 | MEF2D | MEF2D Entrez, Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 3864 | 0.038 | -0.1885 | No |
| 6 | SMAP1L | SMAP1L Entrez, Source | stromal membrane-associated protein 1-like | 4107 | 0.035 | -0.1953 | No |
| 7 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 4345 | 0.032 | -0.2026 | No |
| 8 | TEX2 | TEX2 Entrez, Source | testis expressed sequence 2 | 4438 | 0.031 | -0.1995 | No |
| 9 | SON | SON Entrez, Source | SON DNA binding protein | 5446 | 0.019 | -0.2691 | No |
| 10 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 5552 | 0.018 | -0.2712 | No |
| 11 | DPP10 | DPP10 Entrez, Source | dipeptidyl-peptidase 10 | 5605 | 0.017 | -0.2696 | No |
| 12 | ARHGEF5 | ARHGEF5 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 5 | 6381 | 0.009 | -0.3250 | No |
| 13 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 6472 | 0.008 | -0.3293 | No |
| 14 | TARDBP | TARDBP Entrez, Source | TAR DNA binding protein | 6682 | 0.006 | -0.3432 | No |
| 15 | SH3BP4 | SH3BP4 Entrez, Source | SH3-domain binding protein 4 | 7134 | 0.001 | -0.3769 | No |
| 16 | SAR1A | SAR1A Entrez, Source | SAR1 gene homolog A (S. cerevisiae) | 8302 | -0.013 | -0.4604 | No |
| 17 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 9145 | -0.024 | -0.5160 | No |
| 18 | KIT | KIT Entrez, Source | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 9974 | -0.036 | -0.5664 | Yes |
| 19 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 10023 | -0.037 | -0.5580 | Yes |
| 20 | XYLT2 | XYLT2 Entrez, Source | xylosyltransferase II | 10145 | -0.039 | -0.5543 | Yes |
| 21 | FNBP1 | FNBP1 Entrez, Source | formin binding protein 1 | 10158 | -0.039 | -0.5424 | Yes |
| 22 | HSF2 | HSF2 Entrez, Source | heat shock transcription factor 2 | 10446 | -0.044 | -0.5496 | Yes |
| 23 | CREBL2 | CREBL2 Entrez, Source | cAMP responsive element binding protein-like 2 | 10552 | -0.046 | -0.5425 | Yes |
| 24 | REXO2 | REXO2 Entrez, Source | REX2, RNA exonuclease 2 homolog (S. cerevisiae) | 10632 | -0.048 | -0.5329 | Yes |
| 25 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 10661 | -0.048 | -0.5193 | Yes |
| 26 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 10703 | -0.049 | -0.5063 | Yes |
| 27 | BTG3 | BTG3 Entrez, Source | BTG family, member 3 | 11098 | -0.058 | -0.5171 | Yes |
| 28 | UBE2Z | UBE2Z Entrez, Source | ubiquitin-conjugating enzyme E2Z (putative) | 11150 | -0.059 | -0.5016 | Yes |
| 29 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 11170 | -0.060 | -0.4836 | Yes |
| 30 | SMAD2 | SMAD2 Entrez, Source | SMAD, mothers against DPP homolog 2 (Drosophila) | 11223 | -0.061 | -0.4678 | Yes |
| 31 | PTGFRN | PTGFRN Entrez, Source | prostaglandin F2 receptor negative regulator | 11317 | -0.063 | -0.4543 | Yes |
| 32 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 11349 | -0.064 | -0.4359 | Yes |
| 33 | NEDD9 | NEDD9 Entrez, Source | neural precursor cell expressed, developmentally down-regulated 9 | 11537 | -0.070 | -0.4272 | Yes |
| 34 | NR1H2 | NR1H2 Entrez, Source | nuclear receptor subfamily 1, group H, member 2 | 11613 | -0.073 | -0.4092 | Yes |
| 35 | TRIOBP | TRIOBP Entrez, Source | TRIO and F-actin binding protein | 12179 | -0.096 | -0.4205 | Yes |
| 36 | PIAS3 | PIAS3 Entrez, Source | protein inhibitor of activated STAT, 3 | 12301 | -0.103 | -0.3959 | Yes |
| 37 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12750 | -0.141 | -0.3837 | Yes |
| 38 | TRIM2 | TRIM2 Entrez, Source | tripartite motif-containing 2 | 12840 | -0.154 | -0.3402 | Yes |
| 39 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12991 | -0.186 | -0.2908 | Yes |
| 40 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 13006 | -0.190 | -0.2301 | Yes |
| 41 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 13180 | -0.281 | -0.1517 | Yes |
| 42 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 13313 | -0.503 | 0.0022 | Yes |
