Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | GLUCOSE_METABOLIC_PROCESS |
| Enrichment Score (ES) | 0.5605995 |
| Normalized Enrichment Score (NES) | 1.608707 |
| Nominal p-value | 0.017660044 |
| FDR q-value | 0.09002314 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PDK4 | PDK4 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 4 | 207 | 0.172 | 0.1279 | Yes |
| 2 | GCK | GCK Entrez, Source | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 218 | 0.170 | 0.2688 | Yes |
| 3 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 476 | 0.127 | 0.3559 | Yes |
| 4 | SLC25A10 | SLC25A10 Entrez, Source | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 | 790 | 0.107 | 0.4220 | Yes |
| 5 | ALDOB | ALDOB Entrez, Source | aldolase B, fructose-bisphosphate | 941 | 0.100 | 0.4942 | Yes |
| 6 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 1562 | 0.078 | 0.5128 | Yes |
| 7 | ACN9 | ACN9 Entrez, Source | ACN9 homolog (S. cerevisiae) | 1743 | 0.073 | 0.5606 | Yes |
| 8 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 3579 | 0.042 | 0.4579 | No |
| 9 | HK1 | HK1 Entrez, Source | hexokinase 1 | 5904 | 0.014 | 0.2951 | No |
| 10 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 6549 | 0.007 | 0.2526 | No |
| 11 | GAPDHS | GAPDHS Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | 6630 | 0.006 | 0.2517 | No |
| 12 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 6869 | 0.003 | 0.2367 | No |
| 13 | PDK2 | PDK2 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 2 | 7313 | -0.002 | 0.2048 | No |
| 14 | PDK1 | PDK1 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 1 | 8304 | -0.013 | 0.1414 | No |
| 15 | UGP2 | UGP2 Entrez, Source | UDP-glucose pyrophosphorylase 2 | 8944 | -0.021 | 0.1112 | No |
| 16 | ARPP-19 | ARPP-19 Entrez, Source | - | 8985 | -0.022 | 0.1263 | No |
| 17 | PFKM | PFKM Entrez, Source | phosphofructokinase, muscle | 11295 | -0.062 | 0.0050 | No |
| 18 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 11945 | -0.085 | 0.0271 | No |
| 19 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 12126 | -0.093 | 0.0913 | No |
