Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | GLUTAMATE_METABOLISM |
| Enrichment Score (ES) | 0.5075298 |
| Normalized Enrichment Score (NES) | 1.4654901 |
| Nominal p-value | 0.05458515 |
| FDR q-value | 0.16583121 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.1188 | Yes |
| 2 | CPS1 | CPS1 Entrez, Source | carbamoyl-phosphate synthetase 1, mitochondrial | 236 | 0.162 | 0.2409 | Yes |
| 3 | ABAT | ABAT Entrez, Source | 4-aminobutyrate aminotransferase | 271 | 0.155 | 0.3574 | Yes |
| 4 | PPAT | PPAT Entrez, Source | phosphoribosyl pyrophosphate amidotransferase | 709 | 0.111 | 0.4102 | Yes |
| 5 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 1212 | 0.089 | 0.4413 | Yes |
| 6 | GCLC | GCLC Entrez, Source | glutamate-cysteine ligase, catalytic subunit | 1237 | 0.088 | 0.5075 | Yes |
| 7 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2076 | 0.066 | 0.4958 | No |
| 8 | GFPT1 | GFPT1 Entrez, Source | glutamine-fructose-6-phosphate transaminase 1 | 3414 | 0.044 | 0.4294 | No |
| 9 | GLS2 | GLS2 Entrez, Source | glutaminase 2 (liver, mitochondrial) | 3555 | 0.042 | 0.4514 | No |
| 10 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 4114 | 0.035 | 0.4364 | No |
| 11 | GSS | GSS Entrez, Source | glutathione synthetase | 4963 | 0.024 | 0.3915 | No |
| 12 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5455 | 0.019 | 0.3691 | No |
| 13 | GMPS | GMPS Entrez, Source | guanine monphosphate synthetase | 5619 | 0.017 | 0.3698 | No |
| 14 | GCLM | GCLM Entrez, Source | glutamate-cysteine ligase, modifier subunit | 6039 | 0.012 | 0.3479 | No |
| 15 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 6812 | 0.004 | 0.2931 | No |
| 16 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 8367 | -0.014 | 0.1871 | No |
| 17 | GLS | GLS Entrez, Source | glutaminase | 9032 | -0.022 | 0.1544 | No |
| 18 | NADSYN1 | NADSYN1 Entrez, Source | NAD synthetase 1 | 9506 | -0.029 | 0.1412 | No |
| 19 | GLUL | GLUL Entrez, Source | glutamate-ammonia ligase (glutamine synthetase) | 9734 | -0.033 | 0.1493 | No |
| 20 | GPT | GPT Entrez, Source | glutamic-pyruvate transaminase (alanine aminotransferase) | 12858 | -0.158 | 0.0363 | No |
