Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | GLYCEROPHOSPHOLIPID_METABOLISM |
| Enrichment Score (ES) | 0.43280262 |
| Normalized Enrichment Score (NES) | 1.4311814 |
| Nominal p-value | 0.070886075 |
| FDR q-value | 0.18910502 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PEMT | PEMT Entrez, Source | phosphatidylethanolamine N-methyltransferase | 4 | 0.491 | 0.2530 | Yes |
| 2 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 259 | 0.157 | 0.3150 | Yes |
| 3 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 292 | 0.150 | 0.3900 | Yes |
| 4 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 555 | 0.121 | 0.4328 | Yes |
| 5 | PLA2G5 | PLA2G5 Entrez, Source | phospholipase A2, group V | 2764 | 0.054 | 0.2947 | No |
| 6 | PLCB2 | PLCB2 Entrez, Source | phospholipase C, beta 2 | 3617 | 0.042 | 0.2521 | No |
| 7 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 3783 | 0.039 | 0.2601 | No |
| 8 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 3968 | 0.037 | 0.2653 | No |
| 9 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 4307 | 0.033 | 0.2566 | No |
| 10 | DGKZ | DGKZ Entrez, Source | diacylglycerol kinase, zeta 104kDa | 4311 | 0.032 | 0.2731 | No |
| 11 | AGPAT4 | AGPAT4 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta) | 4985 | 0.024 | 0.2349 | No |
| 12 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 5243 | 0.021 | 0.2264 | No |
| 13 | PCYT1A | PCYT1A Entrez, Source | phosphate cytidylyltransferase 1, choline, alpha | 5532 | 0.018 | 0.2140 | No |
| 14 | CHKA | CHKA Entrez, Source | choline kinase alpha | 5540 | 0.018 | 0.2227 | No |
| 15 | CDS2 | CDS2 Entrez, Source | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | 5721 | 0.016 | 0.2173 | No |
| 16 | PLA2G2A | PLA2G2A Entrez, Source | phospholipase A2, group IIA (platelets, synovial fluid) | 5884 | 0.014 | 0.2124 | No |
| 17 | PCYT1B | PCYT1B Entrez, Source | phosphate cytidylyltransferase 1, choline, beta | 5923 | 0.014 | 0.2166 | No |
| 18 | PLA2G1B | PLA2G1B Entrez, Source | phospholipase A2, group IB (pancreas) | 6366 | 0.009 | 0.1879 | No |
| 19 | CDS1 | CDS1 Entrez, Source | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | 6414 | 0.008 | 0.1887 | No |
| 20 | LYPLA1 | LYPLA1 Entrez, Source | lysophospholipase I | 7261 | -0.001 | 0.1256 | No |
| 21 | AGPAT1 | AGPAT1 Entrez, Source | 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) | 7919 | -0.009 | 0.0807 | No |
| 22 | DGKG | DGKG Entrez, Source | diacylglycerol kinase, gamma 90kDa | 8145 | -0.011 | 0.0695 | No |
| 23 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 8159 | -0.011 | 0.0743 | No |
| 24 | AGPS | AGPS Entrez, Source | alkylglycerone phosphate synthase | 8182 | -0.012 | 0.0786 | No |
| 25 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 8698 | -0.018 | 0.0492 | No |
| 26 | CHKB | CHKB Entrez, Source | choline kinase beta | 9113 | -0.023 | 0.0301 | No |
| 27 | DGKB | DGKB Entrez, Source | diacylglycerol kinase, beta 90kDa | 9856 | -0.034 | -0.0081 | No |
| 28 | LYPLA2 | LYPLA2 Entrez, Source | lysophospholipase II | 9951 | -0.036 | 0.0033 | No |
| 29 | PPAP2C | PPAP2C Entrez, Source | phosphatidic acid phosphatase type 2C | 10457 | -0.044 | -0.0118 | No |
| 30 | CDIPT | CDIPT Entrez, Source | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) | 10904 | -0.054 | -0.0176 | No |
| 31 | PPAP2A | PPAP2A Entrez, Source | phosphatidic acid phosphatase type 2A | 11084 | -0.058 | -0.0013 | No |
| 32 | PLCG1 | PLCG1 Entrez, Source | phospholipase C, gamma 1 | 11883 | -0.083 | -0.0188 | No |
| 33 | LYPLA3 | LYPLA3 Entrez, Source | lysophospholipase 3 (lysosomal phospholipase A2) | 12539 | -0.121 | -0.0058 | No |
| 34 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 12633 | -0.128 | 0.0533 | No |
