Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | GLYCINE_SERINE_AND_THREONINE_METABOLISM |
| Enrichment Score (ES) | 0.6725159 |
| Normalized Enrichment Score (NES) | 2.2453165 |
| Nominal p-value | 0.0 |
| FDR q-value | 3.321621E-4 |
| FWER p-Value | 0.0050 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PEMT | PEMT Entrez, Source | phosphatidylethanolamine N-methyltransferase | 4 | 0.491 | 0.1994 | Yes |
| 2 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 113 | 0.213 | 0.2778 | Yes |
| 3 | CHDH | CHDH Entrez, Source | choline dehydrogenase | 208 | 0.171 | 0.3401 | Yes |
| 4 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 237 | 0.162 | 0.4039 | Yes |
| 5 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 300 | 0.149 | 0.4600 | Yes |
| 6 | SARDH | SARDH Entrez, Source | sarcosine dehydrogenase | 566 | 0.121 | 0.4890 | Yes |
| 7 | AGXT | AGXT Entrez, Source | alanine-glyoxylate aminotransferase (oxalosis I; hyperoxaluria I; glycolicaciduria; serine-pyruvate aminotransferase) | 591 | 0.118 | 0.5353 | Yes |
| 8 | PSPH | PSPH Entrez, Source | phosphoserine phosphatase | 746 | 0.109 | 0.5681 | Yes |
| 9 | GAMT | GAMT Entrez, Source | guanidinoacetate N-methyltransferase | 910 | 0.102 | 0.5973 | Yes |
| 10 | CBS | CBS Entrez, Source | cystathionine-beta-synthase | 1127 | 0.092 | 0.6185 | Yes |
| 11 | CTH | CTH Entrez, Source | cystathionase (cystathionine gamma-lyase) | 1284 | 0.086 | 0.6419 | Yes |
| 12 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 1556 | 0.078 | 0.6533 | Yes |
| 13 | DMGDH | DMGDH Entrez, Source | dimethylglycine dehydrogenase | 1702 | 0.074 | 0.6725 | Yes |
| 14 | AMT | AMT Entrez, Source | aminomethyltransferase | 3552 | 0.042 | 0.5508 | No |
| 15 | PLCB2 | PLCB2 Entrez, Source | phospholipase C, beta 2 | 3617 | 0.042 | 0.5628 | No |
| 16 | SHMT2 | SHMT2 Entrez, Source | serine hydroxymethyltransferase 2 (mitochondrial) | 3728 | 0.040 | 0.5709 | No |
| 17 | AGXT2 | AGXT2 Entrez, Source | alanine-glyoxylate aminotransferase 2 | 4019 | 0.036 | 0.5637 | No |
| 18 | GATM | GATM Entrez, Source | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 4229 | 0.033 | 0.5616 | No |
| 19 | SHMT1 | SHMT1 Entrez, Source | serine hydroxymethyltransferase 1 (soluble) | 4738 | 0.027 | 0.5345 | No |
| 20 | GCAT | GCAT Entrez, Source | glycine C-acetyltransferase (2-amino-3-ketobutyrate coenzyme A ligase) | 4809 | 0.026 | 0.5398 | No |
| 21 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 5177 | 0.022 | 0.5211 | No |
| 22 | CHKA | CHKA Entrez, Source | choline kinase alpha | 5540 | 0.018 | 0.5012 | No |
| 23 | TARS | TARS Entrez, Source | threonyl-tRNA synthetase | 5585 | 0.017 | 0.5049 | No |
| 24 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 5876 | 0.014 | 0.4888 | No |
| 25 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5929 | 0.014 | 0.4904 | No |
| 26 | PLCG2 | PLCG2 Entrez, Source | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 8698 | -0.018 | 0.2898 | No |
| 27 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 8794 | -0.019 | 0.2905 | No |
| 28 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 8816 | -0.019 | 0.2968 | No |
| 29 | CHKB | CHKB Entrez, Source | choline kinase beta | 9113 | -0.023 | 0.2841 | No |
| 30 | PLCG1 | PLCG1 Entrez, Source | phospholipase C, gamma 1 | 11883 | -0.083 | 0.1096 | No |
