Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HADDAD_CD45CD7_PLUS_VS_MINUS_DN |
| Enrichment Score (ES) | -0.5219034 |
| Normalized Enrichment Score (NES) | -1.760063 |
| Nominal p-value | 0.0016420361 |
| FDR q-value | 0.049619123 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 567 | 0.120 | -0.0144 | No |
| 2 | MPDZ | MPDZ Entrez, Source | multiple PDZ domain protein | 1036 | 0.096 | -0.0272 | No |
| 3 | CFH | CFH Entrez, Source | complement factor H | 1213 | 0.089 | -0.0195 | No |
| 4 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 1533 | 0.079 | -0.0251 | No |
| 5 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 1585 | 0.077 | -0.0108 | No |
| 6 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 1653 | 0.076 | 0.0019 | No |
| 7 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 1951 | 0.069 | -0.0042 | No |
| 8 | PRG2 | PRG2 Entrez, Source | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 3258 | 0.046 | -0.0916 | No |
| 9 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 3400 | 0.044 | -0.0918 | No |
| 10 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 3545 | 0.042 | -0.0928 | No |
| 11 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 3666 | 0.041 | -0.0922 | No |
| 12 | GP1BB /// SEPT5 | 3830 | 0.039 | -0.0954 | No | ||
| 13 | PLCB4 | PLCB4 Entrez, Source | phospholipase C, beta 4 | 4026 | 0.036 | -0.1016 | No |
| 14 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 4268 | 0.033 | -0.1120 | No |
| 15 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 4640 | 0.028 | -0.1333 | No |
| 16 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 4779 | 0.027 | -0.1375 | No |
| 17 | MLLT3 | MLLT3 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 5005 | 0.024 | -0.1489 | No |
| 18 | DLK1 | DLK1 Entrez, Source | delta-like 1 homolog (Drosophila) | 5246 | 0.021 | -0.1620 | No |
| 19 | INPP4B | INPP4B Entrez, Source | inositol polyphosphate-4-phosphatase, type II, 105kDa | 5672 | 0.016 | -0.1902 | No |
| 20 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 6751 | 0.005 | -0.2702 | No |
| 21 | HLF | HLF Entrez, Source | hepatic leukemia factor | 6819 | 0.004 | -0.2743 | No |
| 22 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 7586 | -0.005 | -0.3308 | No |
| 23 | RASA1 | RASA1 Entrez, Source | RAS p21 protein activator (GTPase activating protein) 1 | 7619 | -0.005 | -0.3321 | No |
| 24 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 7644 | -0.005 | -0.3326 | No |
| 25 | CHN2 | CHN2 Entrez, Source | chimerin (chimaerin) 2 | 7974 | -0.009 | -0.3553 | No |
| 26 | PDZD2 | PDZD2 Entrez, Source | PDZ domain containing 2 | 8263 | -0.013 | -0.3740 | No |
| 27 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 9669 | -0.032 | -0.4723 | No |
| 28 | HTR1F | HTR1F Entrez, Source | 5-hydroxytryptamine (serotonin) receptor 1F | 9914 | -0.035 | -0.4825 | No |
| 29 | CACNB2 | CACNB2 Entrez, Source | calcium channel, voltage-dependent, beta 2 subunit | 10205 | -0.040 | -0.4949 | No |
| 30 | SERPINI1 | SERPINI1 Entrez, Source | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 10346 | -0.042 | -0.4955 | No |
| 31 | ARMCX2 | ARMCX2 Entrez, Source | armadillo repeat containing, X-linked 2 | 10401 | -0.044 | -0.4894 | No |
| 32 | SMARCA2 | SMARCA2 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | 10834 | -0.052 | -0.5096 | Yes |
| 33 | BCLAF1 | BCLAF1 Entrez, Source | BCL2-associated transcription factor 1 | 10849 | -0.053 | -0.4984 | Yes |
| 34 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 10913 | -0.054 | -0.4904 | Yes |
| 35 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 10930 | -0.054 | -0.4789 | Yes |
| 36 | BAG3 | BAG3 Entrez, Source | BCL2-associated athanogene 3 | 11344 | -0.064 | -0.4951 | Yes |
| 37 | FAM3C | FAM3C Entrez, Source | family with sequence similarity 3, member C | 11530 | -0.070 | -0.4927 | Yes |
| 38 | PTPRD | PTPRD Entrez, Source | protein tyrosine phosphatase, receptor type, D | 11551 | -0.070 | -0.4777 | Yes |
| 39 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 11726 | -0.076 | -0.4729 | Yes |
| 40 | LAPTM4B | LAPTM4B Entrez, Source | lysosomal associated protein transmembrane 4 beta | 12012 | -0.088 | -0.4739 | Yes |
| 41 | ARG2 | ARG2 Entrez, Source | arginase, type II | 12097 | -0.091 | -0.4588 | Yes |
| 42 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12287 | -0.103 | -0.4490 | Yes |
| 43 | TJP2 | TJP2 Entrez, Source | tight junction protein 2 (zona occludens 2) | 12313 | -0.104 | -0.4264 | Yes |
| 44 | F2RL1 | F2RL1 Entrez, Source | coagulation factor II (thrombin) receptor-like 1 | 12440 | -0.114 | -0.4092 | Yes |
| 45 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 12486 | -0.117 | -0.3853 | Yes |
| 46 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 12549 | -0.121 | -0.3615 | Yes |
| 47 | PPM1H | PPM1H Entrez, Source | protein phosphatase 1H (PP2C domain containing) | 12815 | -0.150 | -0.3463 | Yes |
| 48 | GRK5 | GRK5 Entrez, Source | G protein-coupled receptor kinase 5 | 12883 | -0.162 | -0.3135 | Yes |
| 49 | PDE4B | PDE4B Entrez, Source | phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila) | 12954 | -0.177 | -0.2773 | Yes |
| 50 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 12967 | -0.180 | -0.2360 | Yes |
| 51 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12980 | -0.185 | -0.1937 | Yes |
| 52 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 13175 | -0.275 | -0.1437 | Yes |
| 53 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.0734 | Yes |
| 54 | LOX | LOX Entrez, Source | lysyl oxidase | 13251 | -0.352 | 0.0068 | Yes |
