Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HADDAD_HSC_CD10_UP |
| Enrichment Score (ES) | -0.47221223 |
| Normalized Enrichment Score (NES) | -1.7492296 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05001021 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 160 | 0.189 | 0.0069 | No |
| 2 | HIST1H1E | HIST1H1E Entrez, Source | histone cluster 1, H1e | 288 | 0.151 | 0.0125 | No |
| 3 | P2RY14 | P2RY14 Entrez, Source | purinergic receptor P2Y, G-protein coupled, 14 | 519 | 0.124 | 0.0075 | No |
| 4 | HS3ST1 | HS3ST1 Entrez, Source | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 640 | 0.116 | 0.0101 | No |
| 5 | SCN3A | SCN3A Entrez, Source | sodium channel, voltage-gated, type III, alpha | 691 | 0.112 | 0.0175 | No |
| 6 | EFHA1 | EFHA1 Entrez, Source | EF-hand domain family, member A1 | 783 | 0.108 | 0.0215 | No |
| 7 | POU4F1 | POU4F1 Entrez, Source | POU domain, class 4, transcription factor 1 | 968 | 0.099 | 0.0175 | No |
| 8 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 1000 | 0.098 | 0.0249 | No |
| 9 | GH1 | GH1 Entrez, Source | growth hormone 1 | 1265 | 0.087 | 0.0137 | No |
| 10 | CD79B | CD79B Entrez, Source | CD79b molecule, immunoglobulin-associated beta | 1390 | 0.083 | 0.0126 | No |
| 11 | AK1 | AK1 Entrez, Source | adenylate kinase 1 | 1604 | 0.077 | 0.0043 | No |
| 12 | BLK | BLK Entrez, Source | B lymphoid tyrosine kinase | 1772 | 0.073 | -0.0011 | No |
| 13 | KCNJ2 | KCNJ2 Entrez, Source | potassium inwardly-rectifying channel, subfamily J, member 2 | 1778 | 0.073 | 0.0058 | No |
| 14 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 1840 | 0.071 | 0.0084 | No |
| 15 | FOXO1A | FOXO1A Entrez, Source | forkhead box O1A (rhabdomyosarcoma) | 1951 | 0.069 | 0.0070 | No |
| 16 | HIST1H2BH | HIST1H2BH Entrez, Source | histone cluster 1, H2bh | 1973 | 0.069 | 0.0123 | No |
| 17 | RIMS3 | RIMS3 Entrez, Source | regulating synaptic membrane exocytosis 3 | 2026 | 0.067 | 0.0152 | No |
| 18 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 2158 | 0.065 | 0.0117 | No |
| 19 | ELL3 | ELL3 Entrez, Source | elongation factor RNA polymerase II-like 3 | 2237 | 0.063 | 0.0122 | No |
| 20 | PPM1A | PPM1A Entrez, Source | protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform | 2267 | 0.063 | 0.0163 | No |
| 21 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 2319 | 0.062 | 0.0186 | No |
| 22 | QRSL1 | QRSL1 Entrez, Source | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 2371 | 0.061 | 0.0209 | No |
| 23 | MSX1 | MSX1 Entrez, Source | msh homeobox homolog 1 (Drosophila) | 2398 | 0.060 | 0.0250 | No |
| 24 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 2418 | 0.060 | 0.0295 | No |
| 25 | CD9 | CD9 Entrez, Source | CD9 molecule | 2527 | 0.058 | 0.0272 | No |
| 26 | GPM6B | GPM6B Entrez, Source | glycoprotein M6B | 3271 | 0.046 | -0.0243 | No |
| 27 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 3354 | 0.045 | -0.0260 | No |
| 28 | NELF | NELF Entrez, Source | nasal embryonic LHRH factor | 3417 | 0.044 | -0.0263 | No |
| 29 | SEC22B | SEC22B Entrez, Source | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) | 3553 | 0.042 | -0.0322 | No |
| 30 | BLNK | BLNK Entrez, Source | B-cell linker | 3887 | 0.038 | -0.0536 | No |
| 31 | BTG2 | BTG2 Entrez, Source | BTG family, member 2 | 3927 | 0.037 | -0.0528 | No |
| 32 | ALDH5A1 | ALDH5A1 Entrez, Source | aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase) | 4114 | 0.035 | -0.0633 | No |
| 33 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 4258 | 0.033 | -0.0708 | No |
| 34 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 4260 | 0.033 | -0.0676 | No |
| 35 | GNG7 | GNG7 Entrez, Source | guanine nucleotide binding protein (G protein), gamma 7 | 4266 | 0.033 | -0.0647 | No |
| 36 | COL5A1 | COL5A1 Entrez, Source | collagen, type V, alpha 1 | 4268 | 0.033 | -0.0614 | No |
| 37 | LEF1 | LEF1 Entrez, Source | lymphoid enhancer-binding factor 1 | 4464 | 0.030 | -0.0731 | No |
| 38 | CIITA | CIITA Entrez, Source | class II, major histocompatibility complex, transactivator | 4792 | 0.026 | -0.0952 | No |
| 39 | ALOX5 | ALOX5 Entrez, Source | arachidonate 5-lipoxygenase | 4818 | 0.026 | -0.0945 | No |
| 40 | VAMP1 | VAMP1 Entrez, Source | vesicle-associated membrane protein 1 (synaptobrevin 1) | 4878 | 0.025 | -0.0964 | No |
| 41 | LAPTM5 | LAPTM5 Entrez, Source | lysosomal associated multispanning membrane protein 5 | 4925 | 0.025 | -0.0974 | No |
| 42 | RASGRP1 | RASGRP1 Entrez, Source | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | 4950 | 0.024 | -0.0967 | No |
| 43 | CDC2L5 | CDC2L5 Entrez, Source | cell division cycle 2-like 5 (cholinesterase-related cell division controller) | 5085 | 0.023 | -0.1046 | No |
| 44 | WFS1 | WFS1 Entrez, Source | Wolfram syndrome 1 (wolframin) | 5365 | 0.020 | -0.1237 | No |
| 45 | PPM1B | PPM1B Entrez, Source | protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform | 6165 | 0.011 | -0.1830 | No |
| 46 | NID2 | NID2 Entrez, Source | nidogen 2 (osteonidogen) | 6282 | 0.010 | -0.1907 | No |
| 47 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 6400 | 0.009 | -0.1987 | No |
| 48 | AKAP12 | AKAP12 Entrez, Source | A kinase (PRKA) anchor protein (gravin) 12 | 6511 | 0.007 | -0.2063 | No |
| 49 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 7065 | 0.001 | -0.2480 | No |
| 50 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7160 | 0.000 | -0.2551 | No |
| 51 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 7463 | -0.003 | -0.2776 | No |
| 52 | RPS11 | RPS11 Entrez, Source | ribosomal protein S11 | 7504 | -0.004 | -0.2802 | No |
| 53 | TCF4 | TCF4 Entrez, Source | transcription factor 4 | 7631 | -0.005 | -0.2892 | No |
| 54 | STK38 | STK38 Entrez, Source | serine/threonine kinase 38 | 7820 | -0.007 | -0.3027 | No |
| 55 | AP1B1 | AP1B1 Entrez, Source | adaptor-related protein complex 1, beta 1 subunit | 7886 | -0.008 | -0.3068 | No |
| 56 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | -0.3204 | No |
| 57 | VDAC1 | VDAC1 Entrez, Source | voltage-dependent anion channel 1 | 8265 | -0.013 | -0.3330 | No |
| 58 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 8325 | -0.013 | -0.3361 | No |
| 59 | TIA1 | TIA1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein | 8510 | -0.016 | -0.3485 | No |
| 60 | E2F5 | E2F5 Entrez, Source | E2F transcription factor 5, p130-binding | 8663 | -0.018 | -0.3582 | No |
| 61 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 9561 | -0.030 | -0.4230 | No |
| 62 | PTPRE | PTPRE Entrez, Source | protein tyrosine phosphatase, receptor type, E | 9579 | -0.030 | -0.4213 | No |
| 63 | HIST1H4B | HIST1H4B Entrez, Source | histone cluster 1, H4b | 9620 | -0.031 | -0.4212 | No |
| 64 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 9640 | -0.031 | -0.4195 | No |
| 65 | SNN | SNN Entrez, Source | stannin | 9690 | -0.032 | -0.4200 | No |
| 66 | SMARCA4 | SMARCA4 Entrez, Source | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 9879 | -0.034 | -0.4308 | No |
| 67 | ZFP36L1 | ZFP36L1 Entrez, Source | zinc finger protein 36, C3H type-like 1 | 10023 | -0.037 | -0.4379 | No |
| 68 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 10046 | -0.038 | -0.4358 | No |
| 69 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | -0.4382 | No |
| 70 | ING1 | ING1 Entrez, Source | inhibitor of growth family, member 1 | 10309 | -0.042 | -0.4474 | No |
| 71 | DCK | DCK Entrez, Source | deoxycytidine kinase | 10358 | -0.043 | -0.4468 | No |
| 72 | PPP3CC | PPP3CC Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma) | 10460 | -0.045 | -0.4500 | No |
| 73 | CALM1 | CALM1 Entrez, Source | calmodulin 1 (phosphorylase kinase, delta) | 10481 | -0.045 | -0.4470 | No |
| 74 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 10564 | -0.046 | -0.4485 | No |
| 75 | FHIT | FHIT Entrez, Source | fragile histidine triad gene | 10628 | -0.047 | -0.4485 | No |
| 76 | REXO2 | REXO2 Entrez, Source | REX2, RNA exonuclease 2 homolog (S. cerevisiae) | 10632 | -0.048 | -0.4440 | No |
| 77 | TTC13 | TTC13 Entrez, Source | tetratricopeptide repeat domain 13 | 10718 | -0.050 | -0.4454 | No |
| 78 | NEIL1 | NEIL1 Entrez, Source | nei endonuclease VIII-like 1 (E. coli) | 10974 | -0.055 | -0.4591 | No |
| 79 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 11148 | -0.059 | -0.4663 | Yes |
| 80 | CSH2 | CSH2 Entrez, Source | chorionic somatomammotropin hormone 2 | 11208 | -0.060 | -0.4647 | Yes |
| 81 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 11238 | -0.061 | -0.4608 | Yes |
| 82 | SIAH2 | SIAH2 Entrez, Source | seven in absentia homolog 2 (Drosophila) | 11360 | -0.064 | -0.4635 | Yes |
| 83 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 11401 | -0.065 | -0.4600 | Yes |
| 84 | EIF2AK3 | EIF2AK3 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 3 | 11434 | -0.066 | -0.4557 | Yes |
| 85 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 11438 | -0.066 | -0.4493 | Yes |
| 86 | STAG3 | STAG3 Entrez, Source | stromal antigen 3 | 11623 | -0.073 | -0.4559 | Yes |
| 87 | CDKN1B | CDKN1B Entrez, Source | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 11651 | -0.074 | -0.4505 | Yes |
| 88 | HIP1R | HIP1R Entrez, Source | huntingtin interacting protein 1 related | 11863 | -0.082 | -0.4583 | Yes |
| 89 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 11872 | -0.082 | -0.4507 | Yes |
| 90 | MAG | MAG Entrez, Source | myelin associated glycoprotein | 11884 | -0.083 | -0.4432 | Yes |
| 91 | CAPN3 | CAPN3 Entrez, Source | calpain 3, (p94) | 11952 | -0.085 | -0.4398 | Yes |
| 92 | TAF9B | TAF9B Entrez, Source | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 11960 | -0.085 | -0.4317 | Yes |
| 93 | FMR1 | FMR1 Entrez, Source | fragile X mental retardation 1 | 12093 | -0.091 | -0.4325 | Yes |
| 94 | PSPC1 | PSPC1 Entrez, Source | paraspeckle component 1 | 12162 | -0.095 | -0.4282 | Yes |
| 95 | ELF2 | ELF2 Entrez, Source | E74-like factor 2 (ets domain transcription factor) | 12183 | -0.096 | -0.4201 | Yes |
| 96 | DNASE2B | DNASE2B Entrez, Source | deoxyribonuclease II beta | 12211 | -0.097 | -0.4123 | Yes |
| 97 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 12385 | -0.110 | -0.4144 | Yes |
| 98 | TGIF | TGIF Entrez, Source | TGFB-induced factor (TALE family homeobox) | 12388 | -0.110 | -0.4035 | Yes |
| 99 | MOG | MOG Entrez, Source | myelin oligodendrocyte glycoprotein | 12447 | -0.114 | -0.3964 | Yes |
| 100 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 12465 | -0.115 | -0.3861 | Yes |
| 101 | WSB2 | WSB2 Entrez, Source | WD repeat and SOCS box-containing 2 | 12515 | -0.118 | -0.3780 | Yes |
| 102 | P2RX5 | P2RX5 Entrez, Source | purinergic receptor P2X, ligand-gated ion channel, 5 | 12575 | -0.124 | -0.3700 | Yes |
| 103 | UXS1 | UXS1 Entrez, Source | UDP-glucuronate decarboxylase 1 | 12611 | -0.126 | -0.3600 | Yes |
| 104 | ISG20 | ISG20 Entrez, Source | interferon stimulated exonuclease gene 20kDa | 12691 | -0.134 | -0.3526 | Yes |
| 105 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13025 | -0.196 | -0.3580 | Yes |
| 106 | ANKRD10 | ANKRD10 Entrez, Source | ankyrin repeat domain 10 | 13034 | -0.200 | -0.3386 | Yes |
| 107 | NPY | NPY Entrez, Source | neuropeptide Y | 13095 | -0.230 | -0.3200 | Yes |
| 108 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 13215 | -0.309 | -0.2980 | Yes |
| 109 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13220 | -0.314 | -0.2668 | Yes |
| 110 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.2348 | Yes |
| 111 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 13240 | -0.338 | -0.2018 | Yes |
| 112 | MME | MME Entrez, Source | membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase) | 13245 | -0.347 | -0.1673 | Yes |
| 113 | CD69 | CD69 Entrez, Source | CD69 molecule | 13297 | -0.457 | -0.1253 | Yes |
| 114 | DBN1 | DBN1 Entrez, Source | drebrin 1 | 13305 | -0.475 | -0.0782 | Yes |
| 115 | CD24 | CD24 Entrez, Source | CD24 molecule | 13336 | -0.806 | 0.0005 | Yes |
