Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_48h_versus_single_gel_48h.class.cls
#double_gel_48h_versus_single_gel_48h_repos
Phenotypeclass.cls#double_gel_48h_versus_single_gel_48h_repos
Upregulated in classdouble_gel_48h
GeneSetHCC_SURVIVAL_GOOD_VS_POOR_UP
Enrichment Score (ES)0.660675
Normalized Enrichment Score (NES)2.6741815
Nominal p-value0.0
FDR q-value0.0
FWER p-Value0.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: HCC_SURVIVAL_GOOD_VS_POOR_UP   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1EHHADHEHHADH
Entrez,  Source
enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase60.4470.0454Yes
2SLC27A5SLC27A5
Entrez,  Source
solute carrier family 27 (fatty acid transporter), member 5120.3950.0855Yes
3C4BPBC4BPB
Entrez,  Source
complement component 4 binding protein, beta220.3420.1199Yes
4G6PCG6PC
Entrez,  Source
glucose-6-phosphatase, catalytic subunit260.3370.1542Yes
5CDO1CDO1
Entrez,  Source
cysteine dioxygenase, type I540.2790.1807Yes
6AQP9AQP9
Entrez,  Source
aquaporin 9570.2720.2085Yes
7PKLRPKLR
Entrez,  Source
pyruvate kinase, liver and RBC740.2470.2326Yes
8SERPIND1SERPIND1
Entrez,  Source
serpin peptidase inhibitor, clade D (heparin cofactor), member 1830.2400.2566Yes
9CES1CES1
Entrez,  Source
carboxylesterase 1 (monocyte/macrophage serine esterase 1)930.2340.2799Yes
10GLYATGLYAT
Entrez,  Source
glycine-N-acyltransferase1020.2250.3023Yes
11LPIN1LPIN1
Entrez,  Source
lipin 11040.2200.3248Yes
12PCK1PCK1
Entrez,  Source
phosphoenolpyruvate carboxykinase 1 (soluble)1480.1930.3413Yes
13KHKKHK
Entrez,  Source
ketohexokinase (fructokinase)1610.1890.3598Yes
14OTCOTC
Entrez,  Source
ornithine carbamoyltransferase1830.1780.3764Yes
15ABCG5ABCG5
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)1910.1740.3938Yes
16MVKMVK
Entrez,  Source
mevalonate kinase (mevalonic aciduria)1950.1740.4114Yes
17DPYSDPYS
Entrez,  Source
dihydropyrimidinase2420.1610.4244Yes
18PCPC
Entrez,  Source
pyruvate carboxylase2700.1550.4382Yes
19ALAS1ALAS1
Entrez,  Source
aminolevulinate, delta-, synthase 13000.1490.4514Yes
20CABC1CABC1
Entrez,  Source
chaperone, ABC1 activity of bc1 complex homolog (S. pombe)4080.1340.4571Yes
21ACOX2ACOX2
Entrez,  Source
acyl-Coenzyme A oxidase 2, branched chain4420.1300.4679Yes
22HGDHGD
Entrez,  Source
homogentisate 1,2-dioxygenase (homogentisate oxidase)4570.1290.4801Yes
23INSIG1INSIG1
Entrez,  Source
insulin induced gene 14730.1280.4921Yes
24IL6RIL6R
Entrez,  Source
interleukin 6 receptor5490.1220.4989Yes
25CES3CES3
Entrez,  Source
carboxylesterase 3 (brain)6290.1160.5049Yes
26SEC14L2SEC14L2
Entrez,  Source
SEC14-like 2 (S. cerevisiae)7100.1110.5102Yes
27AMACRAMACR
Entrez,  Source
alpha-methylacyl-CoA racemase7350.1100.5196Yes
28INSRINSR
Entrez,  Source
insulin receptor7720.1080.5280Yes
29SLC38A3SLC38A3
Entrez,  Source
solute carrier family 38, member 37790.1080.5386Yes
30SLC25A10SLC25A10
Entrez,  Source
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 107900.1070.5488Yes
31CPT2CPT2
Entrez,  Source
carnitine palmitoyltransferase II8400.1050.5559Yes
32SERPINC1SERPINC1
Entrez,  Source
serpin peptidase inhibitor, clade C (antithrombin), member 18640.1040.5649Yes
33PCYT2PCYT2
Entrez,  Source
phosphate cytidylyltransferase 2, ethanolamine9440.1000.5691Yes
34ACFACF
Entrez,  Source
-9550.0990.5785Yes
35ASGR1ASGR1
Entrez,  Source
asialoglycoprotein receptor 19700.0990.5876Yes
36CYP3A4CYP3A4
Entrez,  Source
cytochrome P450, family 3, subfamily A, polypeptide 49750.0990.5974Yes
37MPDZMPDZ
Entrez,  Source
multiple PDZ domain protein10360.0960.6027Yes
38GJB1GJB1
Entrez,  Source
gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)11070.0930.6069Yes
39SULT2A1SULT2A1
Entrez,  Source
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 111530.0910.6129Yes
40MASP2MASP2
Entrez,  Source
mannan-binding lectin serine peptidase 212540.0880.6143Yes
41F10F10
Entrez,  Source
coagulation factor X13120.0860.6188Yes
42AOX1AOX1
Entrez,  Source
aldehyde oxidase 113650.0840.6235Yes
43MSRAMSRA
Entrez,  Source
methionine sulfoxide reductase A14040.0820.6290Yes
44NDRG2NDRG2
Entrez,  Source
NDRG family member 214560.0810.6335Yes
45PAHPAH
Entrez,  Source
phenylalanine hydroxylase15130.0790.6374Yes
46SLC6A12SLC6A12
Entrez,  Source
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 1215240.0790.6447Yes
47ECHS1ECHS1
Entrez,  Source
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial15280.0790.6525Yes
48BAATBAAT
Entrez,  Source
bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase)16250.0770.6531Yes
49WNT11WNT11
Entrez,  Source
wingless-type MMTV integration site family, member 1117080.0740.6545Yes
50NF1NF1
Entrez,  Source
neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)18030.0720.6548Yes
51TTPATTPA
Entrez,  Source
tocopherol (alpha) transfer protein (ataxia (Friedreich-like) with vitamin E deficiency)18230.0720.6607Yes
52STARD10STARD10
Entrez,  Source
START domain containing 1021920.0640.6395No
53MRPL46MRPL46
Entrez,  Source
mitochondrial ribosomal protein L4622140.0640.6444No
54HAGHHAGH
Entrez,  Source
hydroxyacylglutathione hydrolase26760.0560.6153No
55ARAR
Entrez,  Source
androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease)29310.0510.6014No
56CRYL1CRYL1
Entrez,  Source
crystallin, lambda 130220.0500.5997No
57DCXRDCXR
Entrez,  Source
dicarbonyl/L-xylulose reductase31630.0480.5940No
58SERPING1SERPING1
Entrez,  Source
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)32320.0470.5937No
59APOC3APOC3
Entrez,  Source
apolipoprotein C-III33240.0450.5915No
60HADH2HADH2
Entrez,  Source
hydroxyacyl-Coenzyme A dehydrogenase, type II34210.0440.5888No
61ITPR2ITPR2
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 234680.0430.5898No
62AMTAMT
Entrez,  Source
aminomethyltransferase35520.0420.5878No
63F12F12
Entrez,  Source
coagulation factor XII (Hageman factor)41310.0350.5477No
64PCCBPCCB
Entrez,  Source
propionyl Coenzyme A carboxylase, beta polypeptide42120.0340.5452No
65FMO3FMO3
Entrez,  Source
flavin containing monooxygenase 343480.0320.5382No
66MST1MST1
Entrez,  Source
macrophage stimulating 1 (hepatocyte growth factor-like)47700.0270.5092No
67CPB2CPB2
Entrez,  Source
carboxypeptidase B2 (plasma, carboxypeptidase U)53350.0200.4687No
68SERPINF1SERPINF1
Entrez,  Source
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 153980.0190.4660No
69ZP3ZP3
Entrez,  Source
zona pellucida glycoprotein 3 (sperm receptor)58660.0140.4322No
70CES2CES2
Entrez,  Source
carboxylesterase 2 (intestine, liver)65010.0080.3851No
71SLC2A2SLC2A2
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 267010.0050.3706No
72MUCDHLMUCDHL
Entrez,  Source
mucin and cadherin-like71000.0010.3407No
73NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)71200.0010.3393No
74APCSAPCS
Entrez,  Source
amyloid P component, serum71220.0010.3393No
75APOA5APOA5
Entrez,  Source
apolipoprotein A-V7763-0.0070.2917No
76ACADSACADS
Entrez,  Source
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain7949-0.0090.2786No
77HPDHPD
Entrez,  Source
4-hydroxyphenylpyruvate dioxygenase8248-0.0120.2574No
78EPHX1EPHX1
Entrez,  Source
epoxide hydrolase 1, microsomal (xenobiotic)8371-0.0140.2496No
79KLK3KLK3
Entrez,  Source
kallikrein 3, (prostate specific antigen)8463-0.0150.2443No
80PRDX6PRDX6
Entrez,  Source
peroxiredoxin 68502-0.0160.2430No
81EGLN2EGLN2
Entrez,  Source
egl nine homolog 2 (C. elegans)8706-0.0180.2295No
82MYRIPMYRIP
Entrez,  Source
myosin VIIA and Rab interacting protein9295-0.0260.1878No
83ABCG8ABCG8
Entrez,  Source
ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2)9348-0.0270.1866No
84CABIN1CABIN1
Entrez,  Source
-9647-0.0310.1673No
85PPAP2APPAP2A
Entrez,  Source
phosphatidic acid phosphatase type 2A11084-0.0580.0648No
86ENPP5ENPP5
Entrez,  Source
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function)11441-0.0660.0447No
87IVDIVD
Entrez,  Source
isovaleryl Coenzyme A dehydrogenase11444-0.0660.0514No
88ABHD6ABHD6
Entrez,  Source
abhydrolase domain containing 611685-0.0750.0410No
89C2C2
Entrez,  Source
complement component 211739-0.0770.0448No
90CRATCRAT
Entrez,  Source
carnitine acetyltransferase11766-0.0780.0508No
91SGPL1SGPL1
Entrez,  Source
sphingosine-1-phosphate lyase 111988-0.0860.0430No
92SRD5A1SRD5A1
Entrez,  Source
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)12386-0.1100.0243No
93ABCC2ABCC2
Entrez,  Source
ATP-binding cassette, sub-family C (CFTR/MRP), member 212612-0.1260.0202No
94SELENBP1SELENBP1
Entrez,  Source
selenium binding protein 112740-0.1400.0250No
95RGNRGN
Entrez,  Source
regucalcin (senescence marker protein-30)13030-0.1990.0236No
Table: GSEA details [plain text format]



Fig 2: HCC_SURVIVAL_GOOD_VS_POOR_UP   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: HCC_SURVIVAL_GOOD_VS_POOR_UP: Random ES distribution   
Gene set null distribution of ES for HCC_SURVIVAL_GOOD_VS_POOR_UP