Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HIF1_TARGETS |
| Enrichment Score (ES) | -0.61343974 |
| Normalized Enrichment Score (NES) | -1.8458734 |
| Nominal p-value | 0.0017271157 |
| FDR q-value | 0.032227747 |
| FWER p-Value | 0.881 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 439 | 0.131 | 0.0051 | No |
| 2 | IGFBP1 | IGFBP1 Entrez, Source | insulin-like growth factor binding protein 1 | 459 | 0.129 | 0.0412 | No |
| 3 | TF | TF Entrez, Source | transferrin | 575 | 0.120 | 0.0674 | No |
| 4 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 1769 | 0.073 | -0.0011 | No |
| 5 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 1883 | 0.070 | 0.0109 | No |
| 6 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 2407 | 0.060 | -0.0109 | No |
| 7 | CP | CP Entrez, Source | ceruloplasmin (ferroxidase) | 2438 | 0.060 | 0.0042 | No |
| 8 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 2730 | 0.055 | -0.0018 | No |
| 9 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 3303 | 0.046 | -0.0315 | No |
| 10 | FLT1 | FLT1 Entrez, Source | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 3532 | 0.042 | -0.0362 | No |
| 11 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.2023 | No |
| 12 | HK1 | HK1 Entrez, Source | hexokinase 1 | 5904 | 0.014 | -0.2059 | No |
| 13 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 6404 | 0.008 | -0.2409 | No |
| 14 | GAPDH | GAPDH Entrez, Source | glyceraldehyde-3-phosphate dehydrogenase | 7606 | -0.005 | -0.3297 | No |
| 15 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 8017 | -0.010 | -0.3577 | No |
| 16 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 8185 | -0.012 | -0.3669 | No |
| 17 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 8690 | -0.018 | -0.3995 | No |
| 18 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 9333 | -0.026 | -0.4401 | No |
| 19 | AK3 | AK3 Entrez, Source | adenylate kinase 3 | 9449 | -0.028 | -0.4405 | No |
| 20 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 10267 | -0.041 | -0.4900 | No |
| 21 | HK2 | HK2 Entrez, Source | hexokinase 2 | 10644 | -0.048 | -0.5043 | No |
| 22 | EPO | EPO Entrez, Source | erythropoietin | 11309 | -0.063 | -0.5360 | No |
| 23 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 11945 | -0.085 | -0.5590 | Yes |
| 24 | PFKL | PFKL Entrez, Source | phosphofructokinase, liver | 12126 | -0.093 | -0.5455 | Yes |
| 25 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 13031 | -0.199 | -0.5555 | Yes |
| 26 | ADRA1B | ADRA1B Entrez, Source | adrenergic, alpha-1B-, receptor | 13101 | -0.233 | -0.4928 | Yes |
| 27 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13142 | -0.253 | -0.4223 | Yes |
| 28 | SLC2A1 | SLC2A1 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 1 | 13210 | -0.303 | -0.3392 | Yes |
| 29 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 13226 | -0.322 | -0.2467 | Yes |
| 30 | ADM | ADM Entrez, Source | adrenomedullin | 13274 | -0.393 | -0.1358 | Yes |
| 31 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | 0.0026 | Yes |
