Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HINATA_NFKB_UP |
| Enrichment Score (ES) | -0.52992857 |
| Normalized Enrichment Score (NES) | -1.8675128 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.027363015 |
| FWER p-Value | 0.786 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CTSE | CTSE Entrez, Source | cathepsin E | 170 | 0.184 | 0.0128 | No |
| 2 | GCH1 | GCH1 Entrez, Source | GTP cyclohydrolase 1 (dopa-responsive dystonia) | 441 | 0.131 | 0.0106 | No |
| 3 | IL1RN | IL1RN Entrez, Source | interleukin 1 receptor antagonist | 475 | 0.128 | 0.0259 | No |
| 4 | SLC7A2 | SLC7A2 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 494 | 0.125 | 0.0419 | No |
| 5 | RABEP1 | RABEP1 Entrez, Source | rabaptin, RAB GTPase binding effector protein 1 | 639 | 0.116 | 0.0472 | No |
| 6 | WNT5A | WNT5A Entrez, Source | wingless-type MMTV integration site family, member 5A | 696 | 0.112 | 0.0586 | No |
| 7 | CYP27B1 | CYP27B1 Entrez, Source | cytochrome P450, family 27, subfamily B, polypeptide 1 | 825 | 0.106 | 0.0636 | No |
| 8 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 1050 | 0.095 | 0.0600 | No |
| 9 | IL1B | IL1B Entrez, Source | interleukin 1, beta | 1495 | 0.079 | 0.0375 | No |
| 10 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 1674 | 0.075 | 0.0345 | No |
| 11 | CXCL5 | CXCL5 Entrez, Source | chemokine (C-X-C motif) ligand 5 | 1996 | 0.068 | 0.0198 | No |
| 12 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2163 | 0.065 | 0.0163 | No |
| 13 | CD9 | CD9 Entrez, Source | CD9 molecule | 2527 | 0.058 | -0.0030 | No |
| 14 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 2539 | 0.058 | 0.0042 | No |
| 15 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 2673 | 0.056 | 0.0020 | No |
| 16 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 2775 | 0.054 | 0.0018 | No |
| 17 | NPR1 | NPR1 Entrez, Source | natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | 2976 | 0.050 | -0.0062 | No |
| 18 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 3354 | 0.045 | -0.0284 | No |
| 19 | PLAU | PLAU Entrez, Source | plasminogen activator, urokinase | 3505 | 0.043 | -0.0337 | No |
| 20 | BCL2A1 | BCL2A1 Entrez, Source | BCL2-related protein A1 | 4610 | 0.029 | -0.1130 | No |
| 21 | GTF2H4 | GTF2H4 Entrez, Source | general transcription factor IIH, polypeptide 4, 52kDa | 4669 | 0.028 | -0.1135 | No |
| 22 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 5075 | 0.023 | -0.1408 | No |
| 23 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 5178 | 0.022 | -0.1455 | No |
| 24 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.1904 | No |
| 25 | CDH3 | CDH3 Entrez, Source | cadherin 3, type 1, P-cadherin (placental) | 5905 | 0.014 | -0.1961 | No |
| 26 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 6064 | 0.012 | -0.2064 | No |
| 27 | ARHGDIB | ARHGDIB Entrez, Source | Rho GDP dissociation inhibitor (GDI) beta | 6080 | 0.012 | -0.2058 | No |
| 28 | RAC2 | RAC2 Entrez, Source | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 6150 | 0.011 | -0.2094 | No |
| 29 | MAPK9 | MAPK9 Entrez, Source | mitogen-activated protein kinase 9 | 6392 | 0.009 | -0.2264 | No |
| 30 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 6778 | 0.004 | -0.2548 | No |
| 31 | HGFAC | HGFAC Entrez, Source | HGF activator | 6825 | 0.004 | -0.2577 | No |
| 32 | IL6 | IL6 Entrez, Source | interleukin 6 (interferon, beta 2) | 6864 | 0.004 | -0.2601 | No |
| 33 | ARF6 | ARF6 Entrez, Source | ADP-ribosylation factor 6 | 6899 | 0.003 | -0.2622 | No |
| 34 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 7065 | 0.001 | -0.2745 | No |
| 35 | EFNA1 | EFNA1 Entrez, Source | ephrin-A1 | 7146 | 0.000 | -0.2805 | No |
| 36 | FN1 | FN1 Entrez, Source | fibronectin 1 | 7215 | -0.000 | -0.2855 | No |
| 37 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 8149 | -0.011 | -0.3543 | No |
| 38 | CFLAR | CFLAR Entrez, Source | CASP8 and FADD-like apoptosis regulator | 8465 | -0.015 | -0.3760 | No |
| 39 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 8686 | -0.018 | -0.3901 | No |
| 40 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 9099 | -0.023 | -0.4179 | No |
| 41 | CSF2 | CSF2 Entrez, Source | colony stimulating factor 2 (granulocyte-macrophage) | 9237 | -0.025 | -0.4248 | No |
| 42 | SELE | SELE Entrez, Source | selectin E (endothelial adhesion molecule 1) | 10062 | -0.038 | -0.4816 | No |
| 43 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 10305 | -0.041 | -0.4941 | No |
| 44 | PNRC1 | PNRC1 Entrez, Source | proline-rich nuclear receptor coactivator 1 | 10332 | -0.042 | -0.4902 | No |
| 45 | AP2B1 | AP2B1 Entrez, Source | adaptor-related protein complex 2, beta 1 subunit | 10404 | -0.044 | -0.4895 | No |
| 46 | IER3 | IER3 Entrez, Source | immediate early response 3 | 10439 | -0.044 | -0.4860 | No |
| 47 | SERPINB2 | SERPINB2 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 10863 | -0.053 | -0.5105 | No |
| 48 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 10939 | -0.055 | -0.5085 | No |
| 49 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 11138 | -0.059 | -0.5153 | No |
| 50 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 11186 | -0.060 | -0.5105 | No |
| 51 | TAP1 | TAP1 Entrez, Source | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 11267 | -0.062 | -0.5080 | No |
| 52 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 11510 | -0.069 | -0.5167 | No |
| 53 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 11687 | -0.075 | -0.5195 | Yes |
| 54 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 11740 | -0.077 | -0.5128 | Yes |
| 55 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 11763 | -0.078 | -0.5036 | Yes |
| 56 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 11798 | -0.079 | -0.4952 | Yes |
| 57 | ITGB6 | ITGB6 Entrez, Source | integrin, beta 6 | 11921 | -0.084 | -0.4928 | Yes |
| 58 | ESM1 | ESM1 Entrez, Source | endothelial cell-specific molecule 1 | 12105 | -0.092 | -0.4938 | Yes |
| 59 | NFKB2 | NFKB2 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 12192 | -0.096 | -0.4869 | Yes |
| 60 | RPA2 | RPA2 Entrez, Source | replication protein A2, 32kDa | 12271 | -0.101 | -0.4788 | Yes |
| 61 | IL15 | IL15 Entrez, Source | interleukin 15 | 12279 | -0.102 | -0.4652 | Yes |
| 62 | MAP1B | MAP1B Entrez, Source | microtubule-associated protein 1B | 12487 | -0.117 | -0.4645 | Yes |
| 63 | IRF1 | IRF1 Entrez, Source | interferon regulatory factor 1 | 12531 | -0.120 | -0.4511 | Yes |
| 64 | BMP2 | BMP2 Entrez, Source | bone morphogenetic protein 2 | 12648 | -0.130 | -0.4418 | Yes |
| 65 | WFDC2 | WFDC2 Entrez, Source | WAP four-disulfide core domain 2 | 12814 | -0.150 | -0.4335 | Yes |
| 66 | ABCC1 | ABCC1 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 12872 | -0.160 | -0.4155 | Yes |
| 67 | GABBR1 | GABBR1 Entrez, Source | gamma-aminobutyric acid (GABA) B receptor, 1 | 12893 | -0.163 | -0.3943 | Yes |
| 68 | EDN1 | EDN1 Entrez, Source | endothelin 1 | 13031 | -0.199 | -0.3769 | Yes |
| 69 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 13063 | -0.214 | -0.3495 | Yes |
| 70 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 13092 | -0.227 | -0.3201 | Yes |
| 71 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | -0.2885 | Yes |
| 72 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13241 | -0.343 | -0.2494 | Yes |
| 73 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 13254 | -0.355 | -0.2010 | Yes |
| 74 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 13267 | -0.380 | -0.1490 | Yes |
| 75 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 13308 | -0.484 | -0.0847 | Yes |
| 76 | CCL2 | CCL2 Entrez, Source | chemokine (C-C motif) ligand 2 | 13326 | -0.627 | 0.0012 | Yes |
