Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HOFFMANN_BIVSBII_BI |
| Enrichment Score (ES) | -0.48975855 |
| Normalized Enrichment Score (NES) | -1.6899952 |
| Nominal p-value | 0.0050167223 |
| FDR q-value | 0.071330994 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ELOVL6 | ELOVL6 Entrez, Source | ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 29 | 0.313 | 0.0492 | No |
| 2 | SQLE | SQLE Entrez, Source | squalene epoxidase | 112 | 0.214 | 0.0781 | No |
| 3 | GIMAP4 | GIMAP4 Entrez, Source | GTPase, IMAP family member 4 | 196 | 0.173 | 0.1003 | No |
| 4 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 719 | 0.111 | 0.0791 | No |
| 5 | THY1 | THY1 Entrez, Source | Thy-1 cell surface antigen | 748 | 0.109 | 0.0949 | No |
| 6 | ATP6V0A1 | ATP6V0A1 Entrez, Source | ATPase, H+ transporting, lysosomal V0 subunit a1 | 974 | 0.099 | 0.0941 | No |
| 7 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 1050 | 0.095 | 0.1041 | No |
| 8 | GRB7 | GRB7 Entrez, Source | growth factor receptor-bound protein 7 | 1701 | 0.074 | 0.0673 | No |
| 9 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 1770 | 0.073 | 0.0741 | No |
| 10 | CD9 | CD9 Entrez, Source | CD9 molecule | 2527 | 0.058 | 0.0267 | No |
| 11 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 2775 | 0.054 | 0.0169 | No |
| 12 | DAB2IP | DAB2IP Entrez, Source | DAB2 interacting protein | 3298 | 0.046 | -0.0149 | No |
| 13 | EMB | EMB Entrez, Source | embigin homolog (mouse) | 3384 | 0.045 | -0.0139 | No |
| 14 | TBXA2R | TBXA2R Entrez, Source | thromboxane A2 receptor | 3536 | 0.042 | -0.0184 | No |
| 15 | THRA | THRA Entrez, Source | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 3546 | 0.042 | -0.0121 | No |
| 16 | CRYAA | CRYAA Entrez, Source | crystallin, alpha A | 3740 | 0.040 | -0.0201 | No |
| 17 | GAP43 | GAP43 Entrez, Source | growth associated protein 43 | 3808 | 0.039 | -0.0187 | No |
| 18 | SIPA1 | SIPA1 Entrez, Source | signal-induced proliferation-associated gene 1 | 4121 | 0.035 | -0.0365 | No |
| 19 | ENG | ENG Entrez, Source | endoglin (Osler-Rendu-Weber syndrome 1) | 4137 | 0.035 | -0.0319 | No |
| 20 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 4260 | 0.033 | -0.0357 | No |
| 21 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 4328 | 0.032 | -0.0354 | No |
| 22 | RUNX2 | RUNX2 Entrez, Source | runt-related transcription factor 2 | 4704 | 0.027 | -0.0592 | No |
| 23 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 4735 | 0.027 | -0.0570 | No |
| 24 | STAT4 | STAT4 Entrez, Source | signal transducer and activator of transcription 4 | 5065 | 0.023 | -0.0780 | No |
| 25 | TACSTD2 | TACSTD2 Entrez, Source | tumor-associated calcium signal transducer 2 | 5622 | 0.017 | -0.1171 | No |
| 26 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 5771 | 0.015 | -0.1257 | No |
| 27 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 6186 | 0.011 | -0.1551 | No |
| 28 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 6400 | 0.009 | -0.1697 | No |
| 29 | LMO4 | LMO4 Entrez, Source | LIM domain only 4 | 6509 | 0.007 | -0.1767 | No |
| 30 | MAPK8IP3 | MAPK8IP3 Entrez, Source | mitogen-activated protein kinase 8 interacting protein 3 | 7908 | -0.008 | -0.2806 | No |
| 31 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 8122 | -0.011 | -0.2948 | No |
| 32 | RHOH | RHOH Entrez, Source | ras homolog gene family, member H | 8155 | -0.011 | -0.2954 | No |
| 33 | CTSL | CTSL Entrez, Source | cathepsin L | 8194 | -0.012 | -0.2963 | No |
| 34 | CUBN | CUBN Entrez, Source | cubilin (intrinsic factor-cobalamin receptor) | 8811 | -0.019 | -0.3395 | No |
| 35 | ADA | ADA Entrez, Source | adenosine deaminase | 8863 | -0.020 | -0.3401 | No |
| 36 | ST3GAL6 | ST3GAL6 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 9231 | -0.025 | -0.3637 | No |
| 37 | ENPP1 | ENPP1 Entrez, Source | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 9297 | -0.026 | -0.3643 | No |
| 38 | HEMGN | HEMGN Entrez, Source | hemogen | 9968 | -0.036 | -0.4089 | No |
| 39 | SOCS1 | SOCS1 Entrez, Source | suppressor of cytokine signaling 1 | 10039 | -0.037 | -0.4080 | No |
| 40 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10652 | -0.048 | -0.4462 | No |
| 41 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 10779 | -0.051 | -0.4473 | No |
| 42 | PIK4CB | PIK4CB Entrez, Source | phosphatidylinositol 4-kinase, catalytic, beta polypeptide | 10874 | -0.053 | -0.4457 | No |
| 43 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 11075 | -0.057 | -0.4513 | No |
| 44 | TCN2 | TCN2 Entrez, Source | transcobalamin II; macrocytic anemia | 11172 | -0.060 | -0.4487 | No |
| 45 | AKR1C6 | 11260 | -0.061 | -0.4452 | No | ||
| 46 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 11785 | -0.078 | -0.4718 | No |
| 47 | TLOC1 | TLOC1 Entrez, Source | translocation protein 1 | 12024 | -0.088 | -0.4753 | Yes |
| 48 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 12129 | -0.093 | -0.4678 | Yes |
| 49 | PPIC | PPIC Entrez, Source | peptidylprolyl isomerase C (cyclophilin C) | 12389 | -0.110 | -0.4693 | Yes |
| 50 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12408 | -0.112 | -0.4523 | Yes |
| 51 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 12420 | -0.112 | -0.4348 | Yes |
| 52 | EMP1 | EMP1 Entrez, Source | epithelial membrane protein 1 | 12519 | -0.119 | -0.4226 | Yes |
| 53 | ANXA2 | ANXA2 Entrez, Source | annexin A2 | 12686 | -0.133 | -0.4133 | Yes |
| 54 | MAGED2 | MAGED2 Entrez, Source | melanoma antigen family D, 2 | 12723 | -0.137 | -0.3935 | Yes |
| 55 | ITM2C | ITM2C Entrez, Source | integral membrane protein 2C | 12821 | -0.151 | -0.3760 | Yes |
| 56 | TAX1BP3 | TAX1BP3 Entrez, Source | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 12900 | -0.165 | -0.3548 | Yes |
| 57 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 13027 | -0.198 | -0.3319 | Yes |
| 58 | CHRNB1 | CHRNB1 Entrez, Source | cholinergic receptor, nicotinic, beta 1 (muscle) | 13070 | -0.218 | -0.2994 | Yes |
| 59 | ZYX | ZYX Entrez, Source | zyxin | 13115 | -0.238 | -0.2636 | Yes |
| 60 | FXYD5 | FXYD5 Entrez, Source | FXYD domain containing ion transport regulator 5 | 13131 | -0.248 | -0.2241 | Yes |
| 61 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13303 | -0.473 | -0.1595 | Yes |
| 62 | AHNAK | AHNAK Entrez, Source | AHNAK nucleoprotein (desmoyokin) | 13311 | -0.491 | -0.0795 | Yes |
| 63 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13312 | -0.498 | 0.0023 | Yes |
