Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | single_gel_48h |
| GeneSet | HOFFMANN_BIVSBII_BI_TABLE2 |
| Enrichment Score (ES) | -0.4632698 |
| Normalized Enrichment Score (NES) | -1.7483152 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05013339 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 71 | 0.251 | 0.0234 | No |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 197 | 0.173 | 0.0338 | No |
| 3 | RBP4 | RBP4 Entrez, Source | retinol binding protein 4, plasma | 409 | 0.134 | 0.0332 | No |
| 4 | RAMP1 | RAMP1 Entrez, Source | receptor (calcitonin) activity modifying protein 1 | 530 | 0.123 | 0.0383 | No |
| 5 | RABEP1 | RABEP1 Entrez, Source | rabaptin, RAB GTPase binding effector protein 1 | 639 | 0.116 | 0.0434 | No |
| 6 | IL4 | IL4 Entrez, Source | interleukin 4 | 741 | 0.109 | 0.0483 | No |
| 7 | TUBB3 | TUBB3 Entrez, Source | tubulin, beta 3 | 1042 | 0.096 | 0.0365 | No |
| 8 | CD2 | CD2 Entrez, Source | CD2 molecule | 1336 | 0.085 | 0.0241 | No |
| 9 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 1464 | 0.080 | 0.0237 | No |
| 10 | SPINK1 | SPINK1 Entrez, Source | serine peptidase inhibitor, Kazal type 1 | 1631 | 0.076 | 0.0199 | No |
| 11 | IGH-1A | 1652 | 0.076 | 0.0270 | No | ||
| 12 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 1770 | 0.073 | 0.0265 | No |
| 13 | AZIN1 | AZIN1 Entrez, Source | antizyme inhibitor 1 | 2329 | 0.061 | -0.0086 | No |
| 14 | HCK | HCK Entrez, Source | hemopoietic cell kinase | 2578 | 0.057 | -0.0208 | No |
| 15 | MYH11 | MYH11 Entrez, Source | myosin, heavy chain 11, smooth muscle | 2696 | 0.055 | -0.0233 | No |
| 16 | ITGB7 | ITGB7 Entrez, Source | integrin, beta 7 | 3051 | 0.049 | -0.0444 | No |
| 17 | HES1 | HES1 Entrez, Source | hairy and enhancer of split 1, (Drosophila) | 3122 | 0.048 | -0.0442 | No |
| 18 | AARS | AARS Entrez, Source | alanyl-tRNA synthetase | 3123 | 0.048 | -0.0387 | No |
| 19 | LSP1 | LSP1 Entrez, Source | lymphocyte-specific protein 1 | 3215 | 0.047 | -0.0402 | No |
| 20 | FHL1 | FHL1 Entrez, Source | four and a half LIM domains 1 | 3226 | 0.047 | -0.0355 | No |
| 21 | GJA4 | GJA4 Entrez, Source | gap junction protein, alpha 4, 37kDa (connexin 37) | 3292 | 0.046 | -0.0352 | No |
| 22 | NELF | NELF Entrez, Source | nasal embryonic LHRH factor | 3417 | 0.044 | -0.0395 | No |
| 23 | SEPP1 | SEPP1 Entrez, Source | selenoprotein P, plasma, 1 | 3423 | 0.044 | -0.0348 | No |
| 24 | WT1 | WT1 Entrez, Source | Wilms tumor 1 | 3519 | 0.043 | -0.0371 | No |
| 25 | TBXA2R | TBXA2R Entrez, Source | thromboxane A2 receptor | 3536 | 0.042 | -0.0335 | No |
| 26 | COIL | COIL Entrez, Source | coilin | 3626 | 0.041 | -0.0355 | No |
| 27 | CAMP | CAMP Entrez, Source | cathelicidin antimicrobial peptide | 4148 | 0.034 | -0.0709 | No |
| 28 | NUCKS1 | NUCKS1 Entrez, Source | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 4168 | 0.034 | -0.0684 | No |
| 29 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 4217 | 0.034 | -0.0682 | No |
| 30 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 4303 | 0.033 | -0.0709 | No |
| 31 | PSAT1 | PSAT1 Entrez, Source | phosphoserine aminotransferase 1 | 4505 | 0.030 | -0.0827 | No |
| 32 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 4526 | 0.030 | -0.0808 | No |
| 33 | ANK3 | ANK3 Entrez, Source | ankyrin 3, node of Ranvier (ankyrin G) | 4640 | 0.028 | -0.0861 | No |
| 34 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 4765 | 0.027 | -0.0924 | No |
| 35 | HDH | 4797 | 0.026 | -0.0917 | No | ||
| 36 | ANP32B | ANP32B Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 5054 | 0.023 | -0.1084 | No |
| 37 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 5375 | 0.020 | -0.1304 | No |
| 38 | XPO1 | XPO1 Entrez, Source | exportin 1 (CRM1 homolog, yeast) | 5406 | 0.019 | -0.1304 | No |
| 39 | SPIN | SPIN Entrez, Source | spindlin | 5504 | 0.018 | -0.1357 | No |
| 40 | CCNE1 | CCNE1 Entrez, Source | cyclin E1 | 5568 | 0.017 | -0.1384 | No |
| 41 | HSPD1 | HSPD1 Entrez, Source | heat shock 60kDa protein 1 (chaperonin) | 5662 | 0.016 | -0.1436 | No |
| 42 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 5802 | 0.015 | -0.1524 | No |
| 43 | CHAF1B | CHAF1B Entrez, Source | chromatin assembly factor 1, subunit B (p60) | 5860 | 0.014 | -0.1550 | No |
| 44 | EVL | EVL Entrez, Source | Enah/Vasp-like | 5897 | 0.014 | -0.1562 | No |
| 45 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 5960 | 0.013 | -0.1594 | No |
| 46 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 5981 | 0.013 | -0.1594 | No |
| 47 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 6197 | 0.011 | -0.1744 | No |
| 48 | IGSF10 | IGSF10 Entrez, Source | immunoglobulin superfamily, member 10 | 6383 | 0.009 | -0.1874 | No |
| 49 | WDSUB1 | WDSUB1 Entrez, Source | WD repeat, sterile alpha motif and U-box domain containing 1 | 6580 | 0.007 | -0.2014 | No |
| 50 | ARL1 | ARL1 Entrez, Source | ADP-ribosylation factor-like 1 | 6727 | 0.005 | -0.2119 | No |
| 51 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 6894 | 0.003 | -0.2241 | No |
| 52 | SSX2IP | SSX2IP Entrez, Source | synovial sarcoma, X breakpoint 2 interacting protein | 6954 | 0.002 | -0.2283 | No |
| 53 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 7160 | 0.000 | -0.2437 | No |
| 54 | RPL10 | RPL10 Entrez, Source | ribosomal protein L10 | 7202 | -0.000 | -0.2468 | No |
| 55 | PPIA | PPIA Entrez, Source | peptidylprolyl isomerase A (cyclophilin A) | 7249 | -0.001 | -0.2502 | No |
| 56 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 7306 | -0.001 | -0.2543 | No |
| 57 | CLCN2 | CLCN2 Entrez, Source | chloride channel 2 | 7332 | -0.002 | -0.2559 | No |
| 58 | RAB4B | RAB4B Entrez, Source | RAB4B, member RAS oncogene family | 7405 | -0.003 | -0.2611 | No |
| 59 | PPP2CA | PPP2CA Entrez, Source | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | 7638 | -0.005 | -0.2780 | No |
| 60 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 7712 | -0.006 | -0.2829 | No |
| 61 | JUN | JUN Entrez, Source | jun oncogene | 8081 | -0.010 | -0.3095 | No |
| 62 | EDN2 | EDN2 Entrez, Source | endothelin 2 | 8122 | -0.011 | -0.3113 | No |
| 63 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 8185 | -0.012 | -0.3146 | No |
| 64 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8337 | -0.013 | -0.3245 | No |
| 65 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 8375 | -0.014 | -0.3257 | No |
| 66 | E2F8 | E2F8 Entrez, Source | E2F transcription factor 8 | 8457 | -0.015 | -0.3301 | No |
| 67 | NUDC | NUDC Entrez, Source | nuclear distribution gene C homolog (A. nidulans) | 8595 | -0.017 | -0.3386 | No |
| 68 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 8763 | -0.019 | -0.3490 | No |
| 69 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 8957 | -0.021 | -0.3612 | No |
| 70 | TUBB2C | TUBB2C Entrez, Source | tubulin, beta 2C | 9095 | -0.023 | -0.3689 | No |
| 71 | NT5DC2 | NT5DC2 Entrez, Source | 5'-nucleotidase domain containing 2 | 9286 | -0.026 | -0.3803 | No |
| 72 | AURKA | AURKA Entrez, Source | aurora kinase A | 9722 | -0.032 | -0.4095 | No |
| 73 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 9823 | -0.034 | -0.4132 | No |
| 74 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 10034 | -0.037 | -0.4248 | No |
| 75 | CAPG | CAPG Entrez, Source | capping protein (actin filament), gelsolin-like | 10094 | -0.038 | -0.4249 | No |
| 76 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 10131 | -0.039 | -0.4231 | No |
| 77 | SCN1B | SCN1B Entrez, Source | sodium channel, voltage-gated, type I, beta | 10150 | -0.039 | -0.4200 | No |
| 78 | IER3 | IER3 Entrez, Source | immediate early response 3 | 10439 | -0.044 | -0.4367 | No |
| 79 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 10491 | -0.045 | -0.4354 | No |
| 80 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10652 | -0.048 | -0.4420 | No |
| 81 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 10855 | -0.053 | -0.4513 | No |
| 82 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 10934 | -0.054 | -0.4509 | No |
| 83 | IDE | IDE Entrez, Source | insulin-degrading enzyme | 10957 | -0.055 | -0.4463 | No |
| 84 | KIF4A | KIF4A Entrez, Source | kinesin family member 4A | 11030 | -0.056 | -0.4453 | No |
| 85 | MYEF2 | MYEF2 Entrez, Source | myelin expression factor 2 | 11075 | -0.057 | -0.4420 | No |
| 86 | GPHN | GPHN Entrez, Source | gephyrin | 11082 | -0.058 | -0.4359 | No |
| 87 | FLIIH | 11179 | -0.060 | -0.4363 | No | ||
| 88 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 11242 | -0.061 | -0.4339 | No |
| 89 | TMPO | TMPO Entrez, Source | thymopoietin | 11294 | -0.062 | -0.4307 | No |
| 90 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 11726 | -0.076 | -0.4545 | Yes |
| 91 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 11798 | -0.079 | -0.4509 | Yes |
| 92 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 11841 | -0.081 | -0.4448 | Yes |
| 93 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 11850 | -0.081 | -0.4361 | Yes |
| 94 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 12003 | -0.087 | -0.4376 | Yes |
| 95 | RELN | RELN Entrez, Source | reelin | 12016 | -0.088 | -0.4285 | Yes |
| 96 | GSN | GSN Entrez, Source | gelsolin (amyloidosis, Finnish type) | 12230 | -0.098 | -0.4333 | Yes |
| 97 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 12256 | -0.100 | -0.4237 | Yes |
| 98 | KIF22 | KIF22 Entrez, Source | kinesin family member 22 | 12361 | -0.108 | -0.4193 | Yes |
| 99 | TUBB | TUBB Entrez, Source | tubulin, beta | 12364 | -0.108 | -0.4070 | Yes |
| 100 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12396 | -0.111 | -0.3967 | Yes |
| 101 | CAPN1 | CAPN1 Entrez, Source | calpain 1, (mu/I) large subunit | 12425 | -0.112 | -0.3859 | Yes |
| 102 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12525 | -0.119 | -0.3797 | Yes |
| 103 | CD151 | CD151 Entrez, Source | CD151 molecule (Raph blood group) | 12694 | -0.134 | -0.3770 | Yes |
| 104 | BIRC3 | BIRC3 Entrez, Source | baculoviral IAP repeat-containing 3 | 12722 | -0.137 | -0.3634 | Yes |
| 105 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12734 | -0.139 | -0.3483 | Yes |
| 106 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12798 | -0.147 | -0.3361 | Yes |
| 107 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12842 | -0.155 | -0.3217 | Yes |
| 108 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 12895 | -0.164 | -0.3069 | Yes |
| 109 | PKIB | PKIB Entrez, Source | protein kinase (cAMP-dependent, catalytic) inhibitor beta | 13027 | -0.198 | -0.2941 | Yes |
| 110 | CCNB1 | CCNB1 Entrez, Source | cyclin B1 | 13126 | -0.245 | -0.2734 | Yes |
| 111 | LGALS3 | LGALS3 Entrez, Source | lectin, galactoside-binding, soluble, 3 (galectin 3) | 13164 | -0.267 | -0.2456 | Yes |
| 112 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13211 | -0.304 | -0.2143 | Yes |
| 113 | AURKB | AURKB Entrez, Source | aurora kinase B | 13237 | -0.335 | -0.1778 | Yes |
| 114 | CDC2A | 13238 | -0.335 | -0.1394 | Yes | ||
| 115 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13257 | -0.367 | -0.0987 | Yes |
| 116 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13294 | -0.447 | -0.0502 | Yes |
| 117 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13301 | -0.469 | 0.0031 | Yes |
