Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | HSA00020_CITRATE_CYCLE |
| Enrichment Score (ES) | 0.54181325 |
| Normalized Enrichment Score (NES) | 1.5282089 |
| Nominal p-value | 0.046357617 |
| FDR q-value | 0.1274174 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 127 | 0.202 | 0.1855 | Yes |
| 2 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 148 | 0.193 | 0.3698 | Yes |
| 3 | PC | PC Entrez, Source | pyruvate carboxylase | 270 | 0.155 | 0.5097 | Yes |
| 4 | CLYBL | CLYBL Entrez, Source | citrate lyase beta like | 1994 | 0.068 | 0.4463 | Yes |
| 5 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2853 | 0.052 | 0.4323 | Yes |
| 6 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 3649 | 0.041 | 0.4122 | Yes |
| 7 | MDH2 | MDH2 Entrez, Source | malate dehydrogenase 2, NAD (mitochondrial) | 3660 | 0.041 | 0.4509 | Yes |
| 8 | ACO2 | ACO2 Entrez, Source | aconitase 2, mitochondrial | 3799 | 0.039 | 0.4784 | Yes |
| 9 | IDH3A | IDH3A Entrez, Source | isocitrate dehydrogenase 3 (NAD+) alpha | 3903 | 0.038 | 0.5071 | Yes |
| 10 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 3953 | 0.037 | 0.5392 | Yes |
| 11 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 4559 | 0.029 | 0.5219 | Yes |
| 12 | ACO1 | ACO1 Entrez, Source | aconitase 1, soluble | 4655 | 0.028 | 0.5418 | Yes |
| 13 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 5418 | 0.019 | 0.5030 | No |
| 14 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 5522 | 0.018 | 0.5126 | No |
| 15 | DLD | DLD Entrez, Source | dihydrolipoamide dehydrogenase | 5876 | 0.014 | 0.4998 | No |
| 16 | DLST | DLST Entrez, Source | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 5882 | 0.014 | 0.5130 | No |
| 17 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 6092 | 0.012 | 0.5088 | No |
| 18 | CS | CS Entrez, Source | citrate synthase | 7918 | -0.009 | 0.3801 | No |
| 19 | SUCLG1 | SUCLG1 Entrez, Source | succinate-CoA ligase, GDP-forming, alpha subunit | 8338 | -0.013 | 0.3615 | No |
| 20 | SUCLG2 | SUCLG2 Entrez, Source | succinate-CoA ligase, GDP-forming, beta subunit | 8428 | -0.015 | 0.3688 | No |
