Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_48h_versus_single_gel_48h.class.cls #double_gel_48h_versus_single_gel_48h_repos |
| Phenotype | class.cls#double_gel_48h_versus_single_gel_48h_repos |
| Upregulated in class | double_gel_48h |
| GeneSet | HSA00100_BIOSYNTHESIS_OF_STEROIDS |
| Enrichment Score (ES) | 0.9292829 |
| Normalized Enrichment Score (NES) | 2.8553245 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HSD17B7 | HSD17B7 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 7 | 9 | 0.428 | 0.0850 | Yes |
| 2 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 13 | 0.382 | 0.1612 | Yes |
| 3 | LSS | LSS Entrez, Source | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 20 | 0.353 | 0.2313 | Yes |
| 4 | MVD | MVD Entrez, Source | mevalonate (diphospho) decarboxylase | 21 | 0.352 | 0.3017 | Yes |
| 5 | TM7SF2 | TM7SF2 Entrez, Source | transmembrane 7 superfamily member 2 | 24 | 0.340 | 0.3695 | Yes |
| 6 | FDFT1 | FDFT1 Entrez, Source | farnesyl-diphosphate farnesyltransferase 1 | 44 | 0.291 | 0.4263 | Yes |
| 7 | EBP | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 45 | 0.290 | 0.4843 | Yes |
| 8 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 55 | 0.278 | 0.5392 | Yes |
| 9 | CYP51A1 | CYP51A1 Entrez, Source | cytochrome P450, family 51, subfamily A, polypeptide 1 | 56 | 0.277 | 0.5946 | Yes |
| 10 | PMVK | PMVK Entrez, Source | phosphomevalonate kinase | 73 | 0.247 | 0.6429 | Yes |
| 11 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 90 | 0.236 | 0.6889 | Yes |
| 12 | SQLE | SQLE Entrez, Source | squalene epoxidase | 112 | 0.214 | 0.7301 | Yes |
| 13 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 167 | 0.185 | 0.7629 | Yes |
| 14 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 171 | 0.184 | 0.7994 | Yes |
| 15 | SC5DL | SC5DL Entrez, Source | sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like | 187 | 0.176 | 0.8334 | Yes |
| 16 | MVK | MVK Entrez, Source | mevalonate kinase (mevalonic aciduria) | 195 | 0.174 | 0.8677 | Yes |
| 17 | VKORC1 | VKORC1 Entrez, Source | vitamin K epoxide reductase complex, subunit 1 | 222 | 0.167 | 0.8991 | Yes |
| 18 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 247 | 0.160 | 0.9293 | Yes |
| 19 | CYP27B1 | CYP27B1 Entrez, Source | cytochrome P450, family 27, subfamily B, polypeptide 1 | 825 | 0.106 | 0.9071 | No |
| 20 | NSDHL | NSDHL Entrez, Source | NAD(P) dependent steroid dehydrogenase-like | 1768 | 0.073 | 0.8509 | No |
| 21 | NQO1 | NQO1 Entrez, Source | NAD(P)H dehydrogenase, quinone 1 | 2016 | 0.068 | 0.8459 | No |
| 22 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 5821 | 0.015 | 0.5633 | No |
| 23 | GGPS1 | GGPS1 Entrez, Source | geranylgeranyl diphosphate synthase 1 | 6603 | 0.006 | 0.5059 | No |
